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1MD4
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BU of 1md4 by Molmil
A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to valine
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase
Authors:Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W.
Deposit date:2002-08-06
Release date:2002-08-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1
J.Biol.Chem., 278, 2003
1MD3
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BU of 1md3 by Molmil
A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to alanine
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase
Authors:Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W.
Deposit date:2002-08-06
Release date:2002-08-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1
J.Biol.Chem., 278, 2003
1PX6
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BU of 1px6 by Molmil
A folding mutant of human class pi glutathione transferase, created by mutating aspartate 153 of the wild-type protein to asparagine
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase P
Authors:Kong, G.K.-W, Polekhina, G, McKinstry, W.J, Parker, M.W, Dragani, B, Aceto, A, Paludi, D, Principe, D.R, Mannervik, B, Stenberg, G.
Deposit date:2003-07-02
Release date:2003-07-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The multi-functional role of a highly conserved aspartic acid residue in glutathione transferase P1-1
To be Published
1PX7
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BU of 1px7 by Molmil
A folding mutant of human class pi glutathione transferase, created by mutating aspartate 153 of the wild-type protein to glutamate
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLUTATHIONE, ...
Authors:Kong, G.K.-W, Polekhina, G, McKinstry, W.J, Parker, M.W, Dragani, B, Aceto, A, Paludi, D, Principe, D.R, Mannervik, B, Stenberg, G.
Deposit date:2003-07-02
Release date:2003-07-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The multi-functional role of a highly conserved aspartic acid residue in glutathione transferase P1-1
To be Published
2FK2
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BU of 2fk2 by Molmil
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, Cu(I)-bound
Descriptor: Amyloid beta A4 protein precursor, COPPER (I) ION
Authors:Kong, G.K.-W, Parker, M.W.
Deposit date:2006-01-03
Release date:2007-01-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Studies of the Alzheimer's Amyloid Precursor Protein Copper-binding Domain Reveal How it Binds Copper Ions
J.Mol.Biol., 367, 2007
2FMA
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BU of 2fma by Molmil
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, atomic resolution
Descriptor: Amyloid beta A4 protein precursor, GLYCEROL
Authors:Kong, G.K.-W.
Deposit date:2006-01-08
Release date:2007-01-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:Structure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolution.
Acta Crystallogr.,Sect.F, 63, 2007
2FK3
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BU of 2fk3 by Molmil
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'large unit cell' form
Descriptor: Amyloid beta A4 protein precursor, COPPER (II) ION
Authors:Kong, G.K.-W, Parker, M.W.
Deposit date:2006-01-04
Release date:2007-01-16
Last modified:2022-02-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Studies of the Alzheimer's Amyloid Precursor Protein Copper-binding Domain Reveal How it Binds Copper Ions
J.Mol.Biol., 367, 2007
2FJZ
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BU of 2fjz by Molmil
Structure of the Alzheimer's Amyloid Precursor Protein (APP) copper binding domain (residues 133 to 189) in 'small unit cell' form, metal-free
Descriptor: Amyloid beta A4 protein precursor
Authors:Kong, G.K.-W, Parker, M.W.
Deposit date:2006-01-03
Release date:2007-01-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural Studies of the Alzheimer's Amyloid Precursor Protein Copper-binding Domain Reveal How it Binds Copper Ions
J.Mol.Biol., 367, 2007
2FKL
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BU of 2fkl by Molmil
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain (Residues 126- 189 of APP)
Descriptor: Amyloid beta A4 protein precursor
Authors:Kong, G.K.-W, Parker, M.W.
Deposit date:2006-01-04
Release date:2007-01-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Studies of the Alzheimer's Amyloid Precursor Protein Copper-binding Domain Reveal How it Binds Copper Ions
J.Mol.Biol., 367, 2007
2FK1
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BU of 2fk1 by Molmil
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, Cu(II)-bound
Descriptor: Amyloid beta A4 protein precursor, COPPER (II) ION
Authors:Kong, G.K.-W, Parker, M.W.
Deposit date:2006-01-03
Release date:2007-01-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Studies of the Alzheimer's Amyloid Precursor Protein Copper-binding Domain Reveal How it Binds Copper Ions
J.Mol.Biol., 367, 2007
4XST
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BU of 4xst by Molmil
Structure of the endoglycosidase-H treated L1-CR domains of the human insulin receptor in complex with residues 697-719 of the human insulin receptor (A-isoform)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, SULFATE ION, ...
Authors:Menting, J.G, Lawrence, C.F, Kong, G.K.-W, Lawrence, M.C.
Deposit date:2015-01-22
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors.
Structure, 23, 2015
4XSS
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BU of 4xss by Molmil
Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ...
Authors:Lawrence, C, Kong, G.K.-W, Menting, J.G, Lawrence, M.C.
Deposit date:2015-01-22
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors.
Structure, 23, 2015
3W11
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BU of 3w11 by Molmil
Insulin receptor ectodomain construct comprising domains L1-CR in complex with human insulin, Alpha-CT peptide(704-719) and FAB 83-7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ...
Authors:Lawrence, M.C, Smith, B.J.
Deposit date:2012-11-06
Release date:2013-01-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:How insulin engages its primary binding site on the insulin receptor
Nature, 493, 2013
3W13
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BU of 3w13 by Molmil
Insulin receptor ectodomain construct comprising domains L1-CR in complex with high-affinity insulin analogue [D-PRO-B26]-DTI-NH2, alphact peptide(693-719) and FAB 83-7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ...
Authors:Lawrence, M.C, Smith, B.J, Brzozowski, A.M.
Deposit date:2012-11-06
Release date:2013-01-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (4.303 Å)
Cite:How insulin engages its primary binding site on the insulin receptor
Nature, 493, 2013
3W12
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BU of 3w12 by Molmil
Insulin receptor ectodomain construct comprising domains L1-CR in complex with high-affinity insulin analogue [D-PRO-B26]-DTI-NH2, alpha-CT peptide(704-719) and FAB 83-7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ...
Authors:Lawrence, M.C, Smith, B.J, Brzozowsk, A.M.
Deposit date:2012-11-06
Release date:2013-01-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (4.301 Å)
Cite:How insulin engages its primary binding site on the insulin receptor
Nature, 493, 2013

226707

数据于2024-10-30公开中

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