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3J6U
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BU of 3j6u by Molmil
Cryo-EM structure of Dengue virus serotype 3 in complex with human antibody 5J7 Fab
Descriptor: Fab 5J7 heavy chain, Fab 5J7 light chain, envelope protein, ...
Authors:Fibriansah, G, Tan, J.L, Smith, S.A, de Alwis, R, Ng, T.-S, Kostyuchenko, V.A, Kukkaro, P, de Silva, A.M, Crowe Jr, J.E, Lok, S.-M.
Deposit date:2014-03-26
Release date:2015-03-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9 Å)
Cite:A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins.
Nat Commun, 6, 2015
7MKM
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BU of 7mkm by Molmil
SARS-CoV-2 Spike RBD in complex with neutralizing Fab SARS2-38 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-38 Fv heavy chain, SARS2-38 Fv light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-04-24
Release date:2021-05-12
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
Immunity, 54, 2021
7MKL
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BU of 7mkl by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-38 (three down conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-38 Fv heavy chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-04-24
Release date:2021-05-12
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
Immunity, 54, 2021
6E9I
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BU of 6e9i by Molmil
The crystal structure of bovine ultralong antibody BOV-4
Descriptor: Bovine ultralong antibody BOV-4 heavy chain, Bovine ultralong antibody BOV-4 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9G
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BU of 6e9g by Molmil
The crystal structure of bovine ultralong antibody BOV-2
Descriptor: Bovine ultralong antibody BOV-2 heavy chain, Bovine ultralong antibody BOV-2 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E8V
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BU of 6e8v by Molmil
The crystal structure of bovine ultralong antibody BOV-1
Descriptor: Bovine ultralong antibody BOV-1 Heavy chain, Bovine ultralong antibody BOV-1 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-07-31
Release date:2019-09-04
Last modified:2020-10-21
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9H
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BU of 6e9h by Molmil
The crystal structure of bovine ultralong antibody BOV-3
Descriptor: Bovine ultralong antibody BOV-3 heavy chain, Bovine ultralong antibody BOV-3 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9U
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BU of 6e9u by Molmil
The crystal structure of bovine ultralong antibody BOV-7
Descriptor: Bovine ultralong antibody BOV-7 heavy chain, Bovine ultralong antibody BOV-7 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9K
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BU of 6e9k by Molmil
The crystal structure of bovine ultralong antibody BOV-5
Descriptor: Bovine ultralong antibody BOV-5 heavy chain, IGL@ protein
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Method:X-RAY DIFFRACTION (2.193 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9Q
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BU of 6e9q by Molmil
The crystal structure of bovine ultralong antibody BOV-6
Descriptor: Bovine ultralong antibody BOV-6 heavy chain, Bovine ultralong antibody BOV-6 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6MEG
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BU of 6meg by Molmil
Crystal structure of human monoclonal antibody HEPC46
Descriptor: antibody HEPC46 Heavy Chain, antibody HEPC46 Light Chain
Authors:Flyak, A.I, Bjorkman, P.J.
Deposit date:2018-09-06
Release date:2018-11-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
5KEL
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BU of 5kel by Molmil
EBOV GP in complex with variable Fab domains of IgGs c2G4 and c13C6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ebola surface glycoprotein, ...
Authors:Pallesen, J, Murin, C.D, de Val, N, Cottrell, C.A, Hastie, K.M, Turner, H.L, Fusco, M.L, Flyak, A.I, Zeitlin, L, Crowe Jr, J.E, Andersen, K.G, Saphire, E.O, Ward, A.B.
Deposit date:2016-06-09
Release date:2016-09-07
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Nat Microbiol, 1, 2016
5KEN
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BU of 5ken by Molmil
EBOV GP in complex with variable Fab domains of IgGs c4G7 and c13C6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ebola surface glycoprotein, ...
Authors:Pallesen, J, Murin, C.D, de Val, N, Cottrell, C.A, Hastie, K.M, Turner, H.L, Fusco, M.L, Flyak, A.I, Zeitlin, L, Crowe Jr, J.E, Andersen, K.G, Saphire, E.O, Ward, A.B.
Deposit date:2016-06-09
Release date:2016-09-07
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Nat Microbiol, 1, 2016
5KEM
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BU of 5kem by Molmil
EBOV sGP in complex with variable Fab domains of IgGs c13C6 and BDBV91
Descriptor: BDBV91 variable Fab domain heavy chain, BDBV91 variable Fab domain light chain, Ebola secreted glycoprotein, ...
Authors:Pallesen, J, Murin, C.D, de Val, N, Cottrell, C.A, Hastie, K.M, Turner, H.L, Fusco, M.L, Flyak, A.I, Zeitlin, L, Crowe Jr, J.E, Andersen, K.G, Saphire, E.O, Ward, A.B.
Deposit date:2016-06-09
Release date:2016-09-07
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Nat Microbiol, 1, 2016
6XOB
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BU of 6xob by Molmil
CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP with Fab EEEV-143.
Descriptor: EEEV-143 Fab heavy chain, EEEV-143 Fab light chain, Togavirin
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2020-07-06
Release date:2020-12-23
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Cell, 183, 2020
6XO4
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BU of 6xo4 by Molmil
CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP
Descriptor: Togavirin
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2020-07-06
Release date:2020-12-23
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Cell, 183, 2020
6U02
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BU of 6u02 by Molmil
CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab-63 Heavy Chain, Fab-63 Light Chain, ...
Authors:Ward, A.B, Turner, H.L, Zhu, X.
Deposit date:2019-08-13
Release date:2019-12-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6WDT
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BU of 6wdt by Molmil
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Descriptor: EV68-228 heavy chain, EV68-228 light chain, viral protein 1, ...
Authors:Fu, J, Vogt, M.R, Klose, T, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-01
Release date:2020-07-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
6WDS
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BU of 6wds by Molmil
Enterovirus D68 in complex with human monoclonal antibody EV68-159
Descriptor: EV68-159 heavy chain, EV68-159 light chain, viral protein 1, ...
Authors:Fu, J, Klose, T, Vogt, M.R, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-01
Release date:2020-07-15
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
8DBZ
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BU of 8dbz by Molmil
CryoEM structure of Hantavirus ANDV Gn(H) protein complex with 2Fabs ANDV-5 and ANDV-34
Descriptor: COV44-79 heavy chain constant domain, Fab Fc (L) KappaC, Fv (H) ANDV-34, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2022-06-15
Release date:2023-04-05
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Antigenic mapping and functional characterization of human new world hantavirus neutralizing antibodies.
Elife, 12, 2023
6UIG
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BU of 6uig by Molmil
Crystal structure of human monoclonal antibody H7.200 in complex with H7N9 hemagglutinin HA1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H7.200 Fab heavy chain, H7.200 Fab light chain, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2019-09-30
Release date:2020-10-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Anti-influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface.
J.Clin.Invest., 130, 2020
6V4R
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BU of 6v4r by Molmil
Crystal structure of a chimeric MR78-like antibody chimera-1 Fab
Descriptor: Chimera-1 Fab heavy chain, Chimera-1 Fab light chain
Authors:Bozhanova, N.G, Crowe, J.E, Meiler, J.
Deposit date:2019-11-28
Release date:2020-11-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Discovery of Marburg virus neutralizing antibodies from virus-naive human antibody repertoires using large-scale structural predictions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6V4Q
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BU of 6v4q by Molmil
Crystal structure of a MR78-like antibody naive-1 Fab
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Naive-1 Fab heavy chain, ...
Authors:Bozhanova, N.G, Crowe, J.E, Meiler, J.
Deposit date:2019-11-28
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Discovery of Marburg virus neutralizing antibodies from virus-naive human antibody repertoires using large-scale structural predictions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VY4
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BU of 6vy4 by Molmil
Crystal structure of Hendra receptor binding protein head domain in complex with human neutralizing antibody HENV-32
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-Hendra receptor binding protein antibody HENV-32 Fab heavy chain, Anti-Hendra receptor binding protein antibody HENV-32 Fab light chain, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2020-02-25
Release date:2020-12-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potent Henipavirus Neutralization by Antibodies Recognizing Diverse Sites on Hendra and Nipah Virus Receptor Binding Protein.
Cell, 183, 2020
6VY5
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BU of 6vy5 by Molmil
Crystal structure of Nipah receptor binding protein head domain in complex with human neutralizing antibody HENV-26
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-Hendra receptor binding protein antibody HENV-26 Fab heavy chain, Anti-Hendra receptor binding protein antibody HENV-26 Fab light chain, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2020-02-25
Release date:2021-01-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Potent Henipavirus Neutralization by Antibodies Recognizing Diverse Sites on Hendra and Nipah Virus Receptor Binding Protein.
Cell, 183, 2020

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数据于2024-10-30公开中

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