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6V4R

Crystal structure of a chimeric MR78-like antibody chimera-1 Fab

Summary for 6V4R
Entry DOI10.2210/pdb6v4r/pdb
DescriptorChimera-1 Fab heavy chain, Chimera-1 Fab light chain (2 entities in total)
Functional Keywordsmarburg virus, antibody, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight47494.77
Authors
Bozhanova, N.G.,Crowe, J.E.,Meiler, J. (deposition date: 2019-11-28, release date: 2020-11-25, Last modification date: 2023-10-11)
Primary citationBozhanova, N.G.,Sangha, A.K.,Sevy, A.M.,Gilchuk, P.,Huang, K.,Nargi, R.S.,Reidy, J.X.,Trivette, A.,Carnahan, R.H.,Bukreyev, A.,Crowe Jr., J.E.,Meiler, J.
Discovery of Marburg virus neutralizing antibodies from virus-naive human antibody repertoires using large-scale structural predictions.
Proc.Natl.Acad.Sci.USA, 117:31142-31148, 2020
Cited by
PubMed: 33229516
DOI: 10.1073/pnas.1922654117
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.48 Å)
Structure validation

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