7U5O
| CRYSTAL STRUCTURE OF THE BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE 2 LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-B | Descriptor: | Bone morphogenetic protein receptor type-2, Inhibin beta B chain | Authors: | Chu, K.Y, Malik, A, Thamilselvan, V, Martinez-Hackert, E. | Deposit date: | 2022-03-02 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition. J.Biol.Chem., 298, 2022
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7U5P
| CRYSTAL STRUCTURE OF THE ACTIVIN RECEPTOR TYPE-2A LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2A, Inhibin beta A chain | Authors: | Chu, K.Y, Malik, A, Thamilselvan, V, Martinez-Hackert, E. | Deposit date: | 2022-03-02 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition. J.Biol.Chem., 298, 2022
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2XBM
| Crystal structure of the dengue virus methyltransferase bound to a 5'- capped octameric RNA | Descriptor: | 5'-(*G3AP*GP*AP*AP*CP*CP*UP*GP*A)-3', GLYCEROL, NONSTRUCTURAL PROTEIN NS5, ... | Authors: | Yap, L.J, Luo, D.H, Chung, K.Y, Lim, S.P, Bodenreider, C, Noble, C, Shi, P.Y, Lescar, J. | Deposit date: | 2010-04-13 | Release date: | 2010-09-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of the Dengue Virus Methyltransferase Bound to a 5'-Capped Octameric RNA Plos One, 5, 2010
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3SN6
| Crystal structure of the beta2 adrenergic receptor-Gs protein complex | Descriptor: | 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Camelid antibody VHH fragment, Endolysin,Beta-2 adrenergic receptor, ... | Authors: | Rasmussen, S.G.F, DeVree, B.T, Zou, Y, Kruse, A.C, Chung, K.Y, Kobilka, T.S, Thian, F.S, Chae, P.S, Pardon, E, Calinski, D, Mathiesen, J.M, Shah, S.T.A, Lyons, J.A, Caffrey, M, Gellman, S.H, Steyaert, J, Skiniotis, G, Weis, W.I, Sunahara, R.K, Kobilka, B.K. | Deposit date: | 2011-06-28 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of the beta2 adrenergic receptor-Gs protein complex Nature, 477, 2011
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5DTO
| Dengue virus full length NS5 complexed with viral Cap 0-RNA and SAH | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ACETATE ION, MAGNESIUM ION, ... | Authors: | Zhao, Y, Soh, T.S, Lim, S.P, Chung, K.Y, Swaminathan, K, Vasudevan, S.G, Shi, P.-Y, Lescar, J, Luo, D. | Deposit date: | 2015-09-18 | Release date: | 2015-11-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.603 Å) | Cite: | Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) Proc.Natl.Acad.Sci.USA, 112, 2015
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5EUR
| Hypothetical protein SF216 from shigella flexneri 5a M90T | Descriptor: | MAGNESIUM ION, SULFATE ION, Uncharacterized protein | Authors: | Lee, Y.-S, Seok, S.-H, Kim, H.-N, An, J.-G, Chung, K.Y, Won, H.-S, Seo, M.-D. | Deposit date: | 2015-11-19 | Release date: | 2016-11-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Crystal structure of SF216 from Shigella flexneri strain 5a To Be Published
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1OSY
| Crystal structure of FIP-Fve fungal immunomodulatory protein | Descriptor: | BROMIDE ION, IMMUNOMODULATORY PROTEIN FIP-FVE | Authors: | Palasingam, P, Joseph, J.S, Seow, S.V, Shai, V, Robinson, H, Chua, K.Y, Kolatkar, P.R. | Deposit date: | 2003-03-20 | Release date: | 2003-11-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A 1.7A structure of Fve, a member of the new fungal
immunomodulatory protein family J.Mol.Biol., 332, 2003
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5JT8
| Structural basis for the limited antibody cross reactivity between the mite allergens Blo t 1 and Der p 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Blo t 1 allergen, ... | Authors: | Meno, K, Kastrup, J.S, Gajhede, M. | Deposit date: | 2016-05-09 | Release date: | 2017-05-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of the mite allergen Blo t 1 explains the limited antibody cross-reactivity to Der p 1. Allergy, 72, 2017
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6PFO
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2JMH
| NMR solution structure of Blo t 5, a major mite allergen from Blomia tropicalis | Descriptor: | Mite allergen Blo t 5 | Authors: | Naik, M.T, Chang, C, Kuo, I, Chua, K, Huang, T. | Deposit date: | 2006-11-12 | Release date: | 2007-11-13 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Roles of Structure and Structural Dynamics in the Antibody Recognition of the Allergen Proteins: An NMR Study on Blomia tropicalis Major Allergen Structure, 16, 2008
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8GO9
| Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Atypical chemokine receptor 2, ACKR2 (D6R) | Descriptor: | Atypical chemokine receptor 2, Beta-arrestin-2, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-24 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8HST
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8HSV
| The structure of rat beta-arrestin1 in complex with a rat Mdm2 peptide | Descriptor: | Beta-arrestin-1, SULFATE ION, peptide from E3 ubiquitin-protein ligase Mdm2 | Authors: | Yun, Y, Yoon, H.J, Choi, Y, Lee, H.H. | Deposit date: | 2022-12-20 | Release date: | 2023-07-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | GPCR targeting of E3 ubiquitin ligase MDM2 by inactive beta-arrestin. Proc.Natl.Acad.Sci.USA, 120, 2023
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8J8Z
| Structure of beta-arrestin1 in complex with D6Rpp | Descriptor: | Atypical chemokine receptor 2, Beta-arrestin-1, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J8V
| Structure of beta-arrestin2 in complex with D6Rpp (Local Refine) | Descriptor: | Atypical chemokine receptor 2, Beta-arrestin-2, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J97
| Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local refine, cross-linked) | Descriptor: | Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8JAF
| Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local Refine, non-cross linked) | Descriptor: | Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ... | Authors: | Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K. | Deposit date: | 2023-05-05 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J9K
| Structure of basal beta-arrestin2 | Descriptor: | Beta-arrestin-2, Fab6 heavy chain, Fab6 light chain | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-03 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8JA3
| Structure of beta-arrestin1 in complex with C3aRpp | Descriptor: | Beta-arrestin-1, C3a anaphylatoxin chemotactic receptor, Fab30 heavy chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-05 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8J8R
| Structure of beta-arrestin2 in complex with M2Rpp | Descriptor: | Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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6PJX
| Crystal Structure of G Protein-Coupled Receptor Kinase 5 (GRK5) in Complex with Calmodulin (CaM) | Descriptor: | CALCIUM ION, Calmodulin, G protein-coupled receptor kinase 5, ... | Authors: | Bhardwaj, A, Komolov, K.E, Sulon, S, Benovic, J.L. | Deposit date: | 2019-06-28 | Release date: | 2020-12-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting. Mol.Cell, 81, 2021
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6PGQ
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6C1R
| Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist avacopan | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MALONATE ION, OLEIC ACID, ... | Authors: | Liu, H, Wang, L, Wei, Z, Zhang, C. | Deposit date: | 2018-01-05 | Release date: | 2018-05-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Orthosteric and allosteric action of the C5a receptor antagonists. Nat. Struct. Mol. Biol., 25, 2018
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6C1Q
| Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist NDT9513727 | Descriptor: | 1-(1,3-benzodioxol-5-yl)-~{N}-(1,3-benzodioxol-5-ylmethyl)-~{N}-[(3-butyl-2,5-diphenyl-imidazol-4-yl)methyl]methanamine, PMX53, Soluble cytochrome b562, ... | Authors: | Liu, H, Wang, L, Wei, Z, Zhang, C. | Deposit date: | 2018-01-05 | Release date: | 2018-05-30 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Orthosteric and allosteric action of the C5a receptor antagonists. Nat. Struct. Mol. Biol., 25, 2018
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6JM9
| cryo-EM structure of DOT1L bound to unmodified nucleosome | Descriptor: | DNA strand I, DNA strand J, Histone H2A, ... | Authors: | Jang, S, Song, J.J. | Deposit date: | 2019-03-07 | Release date: | 2019-05-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase. Genes Dev., 33, 2019
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