7YXI
 
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7YXH
 
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7YXJ
 
 | Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and 2,4-PDCA | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GH14974p, ... | Authors: | Chowdhury, R, Schofield, C.J. | Deposit date: | 2022-02-16 | Release date: | 2022-04-27 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans. Sci Rep, 12, 2022
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7YXL
 
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7YXG
 
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7YXK
 
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2Y34
 
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2Y33
 
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6YVW
 
 | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with monocyclic BB-328 | Descriptor: | 4-[(5-bromanyl-4,6-dimethyl-pyridin-2-yl)amino]-4-oxidanylidene-butanoic acid, Egl nine homolog 1, FE (III) ION, ... | Authors: | Chowdhury, R, Banerji, B, Schofield, C.J. | Deposit date: | 2020-04-28 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2. Sci Rep, 10, 2020
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6YW1
 
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6YW2
 
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6YW3
 
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6YVZ
 
 | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic JLS-367 | Descriptor: | 4-[(5-bromanylisoquinolin-3-yl)amino]-4-oxidanylidene-butanoic acid, BICARBONATE ION, Egl nine homolog 1, ... | Authors: | Chowdhury, R, Sorensen, J.L, Schofield, C.J. | Deposit date: | 2020-04-29 | Release date: | 2020-12-30 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2. Sci Rep, 10, 2020
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6YW0
 
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6YVX
 
 | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic BB-287 | Descriptor: | 4-(isoquinolin-3-ylamino)-4-oxobutanoic acid, BICARBONATE ION, Egl nine homolog 1, ... | Authors: | Chowdhury, R, Banerji, B, Schofield, C.J. | Deposit date: | 2020-04-28 | Release date: | 2020-12-30 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2. Sci Rep, 10, 2020
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6YW4
 
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3HQU
 
 | PHD2:Fe:UN9:partial HIF1-alpha substrate complex | Descriptor: | Egl nine homolog 1, FE (II) ION, Hypoxia-inducible factor 1 alpha, ... | Authors: | Chowdhury, R, McDonough, M.A, Schofield, C.J. | Deposit date: | 2009-06-08 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases Structure, 17, 2009
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3HQR
 
 | PHD2:Mn:NOG:HIF1-alpha substrate complex | Descriptor: | Egl nine homolog 1, Hypoxia-inducible factor 1 alpha, MANGANESE (II) ION, ... | Authors: | Chowdhury, R, McDonough, M.A, Schofield, C.J. | Deposit date: | 2009-06-08 | Release date: | 2009-07-28 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases Structure, 17, 2009
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7ZCC
 
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5LAS
 
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5LBC
 
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5LB6
 
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5LBE
 
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5LBB
 
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5L9B
 
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