7YXJ

Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and 2,4-PDCA

Summary for 7YXJ

• Entry DOI: 10.2210/pdb7yxj/pdb
• Descriptor: GH14974p, MANGANESE (II) ION, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, jmjc, jmjc domain, jmjc domain-containing protein 7, jmjd7, jmjc hydroxylase, jmjc demethylase, kdms, post-translational modifications, ptm, hydroxylation, lysyl hydroxylation, dimerisation, translation factor, developmentally regulated gtp binding proteins, drg1, drg2, trafac gtpase, hypoxia, nucleic acid- binding, metal-binding, translation, helix-loop-helix-beta, dsbh, facial triad, development, cancer, ribosome biogenesis
• Biological source: Drosophila melanogaster (fruit fly)
• Total number of polymer chains: 4
• Total formula weight: 148658.47

Authors

Chowdhury, R.,Schofield, C.J. (deposition date: 2022-02-16, release date: 2022-04-27, Last modification date: 2024-01-31)

• Primary citation: Chowdhury, R.,Abboud, M.I.,Wiley, J.,Tumber, A.,Markolovic, S.,Schofield, C.J.; Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans.; Sci Rep, 12:6065-6065, 2022; PubMed: 35410347; DOI: 10.1038/s41598-022-10028-y

Experimental method

X-RAY DIFFRACTION (2.45 Å)