7YXL

Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and N-oxalyl-D-phenylalanine (NOFD)

Summary for 7YXL

Entry DOI	10.2210/pdb7yxl/pdb
Descriptor	GH14974p, MANGANESE (II) ION, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, jmjc, jmjc domain, jmjc domain-containing protein 7, jmjd7, jmjc hydroxylase, jmjc demethylase, kdms, post-translational modifications, ptm, hydroxylation, lysyl hydroxylation, dimerisation, translation factor, developmentally regulated gtp binding proteins, drg1, drg2, trafac gtpase, hypoxia, nucleic acid- binding, metal-binding, translation, helix-loop-helix-beta, dsbh, facial triad, development, cancer, ribosome biogenesis
Biological source	Drosophila melanogaster (fruit fly)
Total number of polymer chains	2
Total formula weight	74614.09
Authors	Chowdhury, R.,Schofield, C.J. (deposition date: 2022-02-16, release date: 2022-04-27, Last modification date: 2024-01-31)
Primary citation	Chowdhury, R.,Abboud, M.I.,Wiley, J.,Tumber, A.,Markolovic, S.,Schofield, C.J. Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans. Sci Rep, 12:6065-6065, 2022 Cited by PubMed: 35410347 DOI: 10.1038/s41598-022-10028-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation