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8S9O
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BU of 8s9o by Molmil
DNA cytosine-N4 methyltransferase (residues 61-324) from the Bdelloid rotifer Adineta vaga - P1 crystal form
Descriptor: 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN
Authors:Zhou, J, Horton, J.R, Cheng, X.
Deposit date:2023-03-29
Release date:2023-08-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga.
J.Biol.Chem., 299, 2023
8SO0
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BU of 8so0 by Molmil
Cryo-EM structure of the PP2A:B55-FAM122A complex
Descriptor: FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, ...
Authors:Fuller, J.R, Padi, S.K.R, Peti, W, Page, R.
Deposit date:2023-04-28
Release date:2023-10-25
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.79961 Å)
Cite:Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
8T0O
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BU of 8t0o by Molmil
Fab from mAb RB2AT_87
Descriptor: CHLORIDE ION, RB2AT_87 Fab Heavy chain, RB2AT_87 Fab Light chain
Authors:Kreutzer, A.G, Malonis, R.J, Lai, J.R, Nowick, J.S.
Deposit date:2023-06-01
Release date:2024-03-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Generation and Study of Antibodies against Two Triangular Trimers Derived from A beta.
Pept Sci (Hoboken), 116, 2024
8SVI
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BU of 8svi by Molmil
Ubiquitin variant i53:Mutant L67H with 53BP1 Tudor domain
Descriptor: GLYCEROL, Tumor protein p53 binding protein 1, Ubiquitin Variant i53: Mutant L67H
Authors:Partridge, J.R, Holden, J.K, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVJ
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BU of 8svj by Molmil
Ubiquitin variant i53: mutant VHH with 53BP1 Tudor domain
Descriptor: GLYCEROL, Tumor protein p53 binding protein 1, Ubiquitin varient i53 mutant VHH
Authors:Holden, J, Partridge, J.R, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVG
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BU of 8svg by Molmil
Ubiquitin variant i53 in complex with 53BP1 Tudor domain
Descriptor: Tumor protein p53 binding protein 1, Ubiquitin variant i53
Authors:Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVH
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BU of 8svh by Molmil
Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain
Descriptor: Tumor protein p53 binding protein 1, Ubiquitin variant i53: mutant L67R
Authors:Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A.
Deposit date:2023-05-16
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SJK
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BU of 8sjk by Molmil
Pembrolizumab Caffeine crystal
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY HEAVY CHAIN, ANTIBODY LIGHT CHAIN, ...
Authors:Larpent, P, Codan, L, Bothe, J.R, Stueber, D, Reichert, P, Fischmann, T, Su, Y, Pabit, S, Gupta, S, Iuzzolino, L, Cote, A.
Deposit date:2023-04-18
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Smaall angle X-ray scattering as powerful toolsfor phase and crystallinity assessment of monoclonal antibodies crystallites in support of batch crystallization and processing
To Be Published
8SZ4
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BU of 8sz4 by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state showing the PH domain
Descriptor: Dynamin-1
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-05-26
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8SXZ
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BU of 8sxz by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-05-24
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8SZ7
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BU of 8sz7 by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state showing the second PH domain
Descriptor: Dynamin-1
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-05-27
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8T0R
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BU of 8t0r by Molmil
Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state (full helix)
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-06-01
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8SH7
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BU of 8sh7 by Molmil
TUBB4B and TUBA1A Heterodimer from Human Respiratory Doublet Microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Anderson, J.R, Gui, M, Brown, A.
Deposit date:2023-04-13
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:TUBB4B variants specifically impact ciliary function, causing a ciliopathic spectrum
To Be Published
8T0K
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BU of 8t0k by Molmil
Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-06-01
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8SZ8
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BU of 8sz8 by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state (full helix)
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-05-27
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8U4U
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BU of 8u4u by Molmil
Crystal structure of 53BP1 tandem Tudor domain homodimer engineered with two disulfide bridges
Descriptor: TP53-binding protein 1
Authors:Cui, G, Botuyan, M.V, Thompson, J.R, Mer, G.
Deposit date:2023-09-11
Release date:2023-09-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Nat Commun, 14, 2023
8TWI
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BU of 8twi by Molmil
Cryo-EM structure of the PP2A:B55-FAM122A complex, PP2Ac body
Descriptor: FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Fuller, J.R, Padi, S.K.R, Peti, W, Page, R.
Deposit date:2023-08-21
Release date:2023-11-01
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
8TWE
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BU of 8twe by Molmil
Cryo-EM structure of the PP2A:B55-FAM122A complex, B55 body
Descriptor: PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Fuller, J.R, Padi, S.K.R, Peti, W, Page, R.
Deposit date:2023-08-21
Release date:2023-11-01
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
8TTB
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BU of 8ttb by Molmil
Cryo-EM structure of the PP2A:B55-ARPP19 complex
Descriptor: FE (III) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Fuller, J.R, Padi, S.K.R, Peti, W, Page, R.
Deposit date:2023-08-13
Release date:2023-10-25
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19.
Nature, 625, 2024
8T9U
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BU of 8t9u by Molmil
Human PU.1 ETS-domain (165-270) in complex with d(AATAAGCGIAAGTGGG)
Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*IP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ...
Authors:Terrell, J.R, Poon, G.M.K.
Deposit date:2023-06-26
Release date:2023-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Dissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Structure, 32, 2024
8T2D
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BU of 8t2d by Molmil
Ubiquitin variant i53:Mutant T12Y.T14E.L67R with 53BP1 Tudor domain
Descriptor: Tumor protein p53 binding protein 1, Ubiquitin variant i53
Authors:Partridge, J.R, Holden, J.K, Wibowo, A.S, Mulichak, A.
Deposit date:2023-06-05
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8TYM
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BU of 8tym by Molmil
Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-08-25
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8T4N
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BU of 8t4n by Molmil
DB1976 Bound to the DNA Sequence 5'-CGCGAATTCGCG-3
Descriptor: (2M,2'M)-2,2'-(selenophene-2,5-diyl)di(1H-benzimidazole-6-carboximidamide), DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Terrell, J.R, Poon, G.M.K, Wilson, W.D.
Deposit date:2023-06-09
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural studies on the PU.1 inhibitory mechanism by diamidine minor groove binders
To Be Published
8TYN
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BU of 8tyn by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state (tetramer model)
Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
Deposit date:2023-08-25
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8W4P
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BU of 8w4p by Molmil
Structure of PSII-FCPII-I/J/K complex in the PSII-FCPII supercomplex from Cyclotella meneghiniana
Descriptor: (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, CHLOROPHYLL A, ...
Authors:Shen, L.L, Li, Z.H, Shen, J.R, Wang, W.D.
Deposit date:2023-08-24
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structural insights into photosystem II supercomplex and trimeric FCP antennae of a centric diatom Cyclotella meneghiniana.
Nat Commun, 14, 2023

221716

数据于2024-06-26公开中

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