1SKG
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![BU of 1skg by Molmil](/molmil-images/mine/1skg) | Structure-based rational drug design: Crystal structure of the complex formed between Phospholipase A2 and a pentapeptide Val-Ala-Phe-Arg-Ser | Descriptor: | METHANOL, Phospholipase A2, SULFATE ION, ... | Authors: | Ethayathulla, A.S, Singh, N, Sharma, S, Makker, J, Dey, S, Perbandt, M, Betzel, C, Singh, T.P. | Deposit date: | 2004-03-04 | Release date: | 2004-04-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Structure-based rational drug design: Crystal structure of the complex formed between Phospholipase A2 and a pentapeptide Val-Ala-Phe-Arg-Ser To be Published
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2VFG
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![BU of 2vfg by Molmil](/molmil-images/mine/2vfg) | Crystal structure of the F96H mutant of Plasmodium falciparum triosephosphate isomerase with 3-phosphoglycerate bound at the dimer interface | Descriptor: | 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | Deposit date: | 2007-11-04 | Release date: | 2008-12-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site. Acta Crystallogr.,Sect.D, 65, 2009
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2PWA
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![BU of 2pwa by Molmil](/molmil-images/mine/2pwa) | Crystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolution | Descriptor: | ALANINE BORONIC ACID, CALCIUM ION, NITRATE ION, ... | Authors: | Jain, R, Singh, N, Perbandt, M, Betzel, C, Sharma, S, Kaur, P, Srinivasan, A, Singh, T.P. | Deposit date: | 2007-05-11 | Release date: | 2007-05-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (0.83 Å) | Cite: | Crystal structure of the complex of Proteinase K with Alanine Boronic Acid at 0.83A Resolution To be Published
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2VFD
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![BU of 2vfd by Molmil](/molmil-images/mine/2vfd) | Crystal structure of the F96S mutant of Plasmodium falciparum triosephosphate isomerase | Descriptor: | SULFATE ION, TRIOSEPHOSPHATE ISOMERASE | Authors: | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | Deposit date: | 2007-11-03 | Release date: | 2008-12-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site. Acta Crystallogr.,Sect.D, 65, 2009
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2VFH
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![BU of 2vfh by Molmil](/molmil-images/mine/2vfh) | Crystal structure of the F96W mutant of Plasmodium falciparum triosephosphate isomerase complexed with 3-phosphoglycerate | Descriptor: | 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | Deposit date: | 2007-11-04 | Release date: | 2008-12-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site. Acta Crystallogr.,Sect.D, 65, 2009
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2VAL
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![BU of 2val by Molmil](/molmil-images/mine/2val) | Crystal structure of an Escherichia coli tRNAGly microhelix at 2.0 Angstrom resolution | Descriptor: | 5'-R(*GP*CP*GP*GP*GP*AP*AP)-3', 5'-R(*UP*UP*CP*CP*CP*GP*CP)-3', MAGNESIUM ION | Authors: | Forster, C, Brauer, A.B.E, Perbandt, M, Lehmann, D, Furste, J.P, Betzel, C, Erdmann, V.A. | Deposit date: | 2007-09-03 | Release date: | 2007-10-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of an Escherichia Coli Trnagly Microhelix at 2.0 Angstrom Resolution Biochem.Biophys.Res.Commun., 363, 2007
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2VFE
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![BU of 2vfe by Molmil](/molmil-images/mine/2vfe) | Crystal structure of F96S mutant of Plasmodium falciparum triosephosphate isomerase with 3- phosphoglycerate bound at the dimer interface | Descriptor: | 3-PHOSPHOGLYCERIC ACID, GLYCEROL, TRIOSEPHOSPHATE ISOMERASE | Authors: | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | Deposit date: | 2007-11-03 | Release date: | 2008-12-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site. Acta Crystallogr.,Sect.D, 65, 2009
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2VFF
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![BU of 2vff by Molmil](/molmil-images/mine/2vff) | Crystal structure of the F96H mutant of Plasmodium falciparum triosephosphate isomerase | Descriptor: | TRIOSEPHOSPHATE ISOMERASE | Authors: | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | Deposit date: | 2007-11-04 | Release date: | 2008-12-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site. Acta Crystallogr.,Sect.D, 65, 2009
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1TDV
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![BU of 1tdv by Molmil](/molmil-images/mine/1tdv) | Non-specific binding to phospholipase A2:Crystal structure of the complex of PLA2 with a designed peptide Tyr-Trp-Ala-Ala-Ala-Ala at 1.7A resolution | Descriptor: | Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, YWAAAA | Authors: | Singh, N, Jabeen, T, Ethayathulla, A.S, Somvanshi, R.K, Sharma, S, Dey, S, Perbandt, M, Betzel, C, Singh, T.P. | Deposit date: | 2004-05-24 | Release date: | 2004-06-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Non-specific binding to phospholipase A2:Crystal structure of the complex of PLA2 with a designed peptide Tyr-Trp-Ala-Ala-Ala-Ala at 1.7A resolution to be published
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2YVV
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![BU of 2yvv by Molmil](/molmil-images/mine/2yvv) | Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites | Descriptor: | Hyaluronidase, phage associated, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Mishra, P, Prem Kumar, R, Singh, N, Sharma, S, Kaur, P, Perbandt, M, Betzel, C, Bhakuni, V, Singh, T.P. | Deposit date: | 2007-04-16 | Release date: | 2007-05-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites To be Published
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2YW0
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![BU of 2yw0 by Molmil](/molmil-images/mine/2yw0) | Crystal structure of hyluranidase trimer at 2.6 A resolution | Descriptor: | Hyaluronidase, phage associated | Authors: | Prem Kumar, R, Mishra, P, Singh, N, Perbandt, M, Kaur, P, Sharma, S, Betzel, C, Bhakuni, V, Singh, T.P. | Deposit date: | 2007-04-18 | Release date: | 2007-05-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Polysaccharide binding sites in hyaluronate lyase--crystal structures of native phage-encoded hyaluronate lyase and its complexes with ascorbic acid and lactose Febs J., 276, 2009
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2YX2
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![BU of 2yx2 by Molmil](/molmil-images/mine/2yx2) | Crystal structure of cloned trimeric hyluranidase from streptococcus pyogenes at 2.8 A resolution | Descriptor: | Hyaluronidase, phage associated | Authors: | Mishra, P, Prem Kumar, R, Bhakuni, V, Singh, N, Sharma, S, Kaur, P, Perbandt, M, Betzel, C, Singh, T.P. | Deposit date: | 2007-04-23 | Release date: | 2007-05-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of cloned trimeric hyluranidase from streptococcus pyogenes at 2.8 A resolution To be Published
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3SIM
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![BU of 3sim by Molmil](/molmil-images/mine/3sim) | Crystallographic structure analysis of family 18 Chitinase from Crocus vernus | Descriptor: | ACETATE ION, GLYCEROL, Protein, ... | Authors: | Akrem, A, Iqbal, S, Buck, F, Negm, A, Perbandt, M, Betzel, C. | Deposit date: | 2011-06-19 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystallographic structure analysis of family 18 Chitinase from Crocus vernus TO BE PUBLISHED
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2W89
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![BU of 2w89 by Molmil](/molmil-images/mine/2w89) | Crystal structure of the E.coli tRNAArg aminoacyl stem issoacceptor RR-1660 at 2.0 Angstroem resolution | Descriptor: | 5'-R(*CP*GP*GP*AP*UP*GP*CP)-3', 5'-R(*GP*CP*AP*UP*CP*CP*GP)-3', GLYCEROL | Authors: | Eichert, A, Schreiber, A, Fuerste, J.P, Perbandt, M, Betzel, C, Erdmann, V.A, Foerster, C. | Deposit date: | 2009-01-15 | Release date: | 2009-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the E. Coli tRNA(Arg) Aminoacyl Stem Isoacceptor Rr-1660 at 2.0 A Resolution. Biochem.Biophys.Res.Commun., 385, 2009
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2VUQ
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![BU of 2vuq by Molmil](/molmil-images/mine/2vuq) | Crystal structure of a human tRNAGly acceptor stem microhelix (derived from the gene sequence DG9990) at 1.18 Angstroem resolution | Descriptor: | 5'-R(*CP*CP*AP*AP*UP*GP*CP)-3', 5'-R(*GP*CP*AP*UP*UP*GP*GP)-3' | Authors: | Eichert, A, Perbandt, M, Schreiber, A, Fuerste, J.P, Betzel, C, Erdmann, V.A, Foerster, C. | Deposit date: | 2008-05-29 | Release date: | 2009-03-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Crystal Structure of the Human Trnagly Microhelix Isoacceptor G9990 at 1.18 A Resolution Biochem.Biophys.Res.Commun., 380, 2009
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3UOU
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![BU of 3uou by Molmil](/molmil-images/mine/3uou) | Crystal structure of the Kunitz-type protease inhibitor ShPI-1 Lys13Leu mutant in complex with pancreatic elastase | Descriptor: | Chymotrypsin-like elastase family member 1, GLYCEROL, Kunitz-type proteinase inhibitor SHPI-1, ... | Authors: | Garcia-Fernandez, R, Perbandt, M, Rehders, D, Gonzalez-Gonzalez, Y, Chavez, M.A, Betzel, C, Redecke, L. | Deposit date: | 2011-11-17 | Release date: | 2012-11-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme. J.Biol.Chem., 290, 2015
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1IC6
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![BU of 1ic6 by Molmil](/molmil-images/mine/1ic6) | STRUCTURE OF A SERINE PROTEASE PROTEINASE K FROM TRITIRACHIUM ALBUM LIMBER AT 0.98 A RESOLUTION | Descriptor: | CALCIUM ION, NITRATE ION, PROTEINASE K | Authors: | Betzel, C, Gourinath, S, Kumar, P, Kaur, P, Perbandt, M, Eschenburg, S, Singh, T.P. | Deposit date: | 2001-03-30 | Release date: | 2001-04-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution. Biochemistry, 40, 2001
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1CE7
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![BU of 1ce7 by Molmil](/molmil-images/mine/1ce7) | MISTLETOE LECTIN I FROM VISCUM ALBUM | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (RIBOSOME-INACTIVATING PROTEIN TYPE II) | Authors: | Krauspenhaar, R, Eschenburg, S, Perbandt, M, Kornilov, V, Konareva, N, Mikailova, I, Stoeva, S, Wacker, R, Maier, T, Singh, T.P, Mikhailov, A, Voelter, W, Betzel, C. | Deposit date: | 1999-03-18 | Release date: | 2000-03-20 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of mistletoe lectin I from Viscum album. Biochem.Biophys.Res.Commun., 257, 1999
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1G8T
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![BU of 1g8t by Molmil](/molmil-images/mine/1g8t) | SM ENDONUCLEASE FROM SERATIA MARCENSCENS AT 1.1 A RESOLUTION | Descriptor: | MAGNESIUM ION, NUCLEASE SM2 ISOFORM, SULFATE ION | Authors: | Lunin, V.V, Perbandt, M, Betzel, C.H, Mikhailov, A.M. | Deposit date: | 2000-11-21 | Release date: | 2000-12-06 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Atomic structure of the Serratia marcescens endonuclease at 1.1 A resolution and the enzyme reaction mechanism. Acta Crystallogr.,Sect.D, 56, 2000
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2H6R
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![BU of 2h6r by Molmil](/molmil-images/mine/2h6r) | Crystal Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii | Descriptor: | Triosephosphate isomerase | Authors: | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | Deposit date: | 2006-06-01 | Release date: | 2007-02-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii Acta Crystallogr.,Sect.D, 63, 2007
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3ZVE
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![BU of 3zve by Molmil](/molmil-images/mine/3zve) | 3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 84 | Descriptor: | 3C PROTEASE, O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonyl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide | Authors: | Tan, J, Perbandt, M, Mesters, J.R, Hilgenfeld, R. | Deposit date: | 2011-07-24 | Release date: | 2012-08-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | 3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses. J.Virol., 87, 2013
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3ZVB
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![BU of 3zvb by Molmil](/molmil-images/mine/3zvb) | 3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 81 | Descriptor: | 3C PROTEASE, ETHYL (4R)-4-{[N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANYL]AMINO}-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE | Authors: | Tan, J, Perbandt, M, Mesters, J.R, Hilgenfeld, R. | Deposit date: | 2011-07-24 | Release date: | 2012-08-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | 3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses. J.Virol., 87, 2013
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3ZVC
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![BU of 3zvc by Molmil](/molmil-images/mine/3zvc) | 3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 82 | Descriptor: | 3C PROTEASE, ETHYL (5S,8S,11R)-8-BENZYL-5-(3-TERT-BUTOXY-3-OXOPROPYL)-3,6,9-TRIOXO-11-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}-1-PHENYL-2-OXA-4,7,10-TRIAZATETRADECAN-14-OATE | Authors: | Tan, J, Perbandt, M, Mesters, J.R, Hilgenfeld, R. | Deposit date: | 2011-07-24 | Release date: | 2012-08-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses. J.Virol., 87, 2013
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4AOF
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![BU of 4aof by Molmil](/molmil-images/mine/4aof) | Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma | Descriptor: | N-[6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]ethanamide, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | Authors: | Bergamini, G, Bell, K, Shimamura, S, Werner, T, Cansfield, A, Muller, K, Perrin, J, Rau, C, Ellard, K, Hopf, C, Doce, C, Leggate, D, Mangano, R, Mathieson, T, OMahony, A, Plavec, I, Rharbaoui, F, Reinhard, F, Savitski, M.M, Ramsden, N, Hirsch, E, Drewes, G, Rausch, O, Bantscheff, M, Neubauer, G. | Deposit date: | 2012-03-26 | Release date: | 2012-05-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A Selective Inhibitor Reveals Pi3Kgamma Dependence of T(H)17 Cell Differentiation. Nat.Chem.Biol., 8, 2012
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3ZV8
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![BU of 3zv8 by Molmil](/molmil-images/mine/3zv8) | |