3ZV8
Crystal structure of 3C protease of Enterovirus 68
Summary for 3ZV8
| Entry DOI | 10.2210/pdb3zv8/pdb |
| Related | 3ZV9 3ZVA 3ZVB 3ZVC 3ZVD 3ZVE 3ZVF 3ZVG |
| Descriptor | 3C PROTEASE (2 entities in total) |
| Functional Keywords | hydrolase, michael inhibitor |
| Biological source | HUMAN ENTEROVIRUS |
| Total number of polymer chains | 1 |
| Total formula weight | 21163.02 |
| Authors | Tan, J.,Perbandt, M.,Mesters, J.R.,Hilgenfeld, R. (deposition date: 2011-07-24, release date: 2012-08-08, Last modification date: 2023-12-20) |
| Primary citation | Tan, J.,George, S.,Kusov, Y.,Perbandt, M.,Anemuller, S.,Mesters, J.R.,Norder, H.,Coutard, B.,Lacroix, C.,Leyssen, P.,Neyts, J.,Hilgenfeld, R. 3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects Against Picornaviruses. J.Virol., 87:4339-, 2013 Cited by PubMed: 23388726DOI: 10.1128/JVI.01123-12 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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