2VFG

Crystal structure of the F96H mutant of Plasmodium falciparum triosephosphate isomerase with 3-phosphoglycerate bound at the dimer interface

Summary for 2VFG

Entry DOI	10.2210/pdb2vfg/pdb
Related	1LYX 1LZO 1M7O 1M7P 1O5X 1VGA 1WOA 1WOB 1YDV 2VFD 2VFE 2VFF 2VFH 2VFI
Descriptor	TRIOSEPHOSPHATE ISOMERASE, 3-PHOSPHOGLYCERIC ACID (3 entities in total)
Functional Keywords	plasmodium falciparum, fatty acid biosynthesis, triosephosphate isomerase, pentose shunt, gluconeogenesis, lipid synthesis, tim, mutant, loop open, isomerase, glycolysis
Biological source	PLASMODIUM FALCIPARUM (MALARIAL PARASITE)
Total number of polymer chains	4
Total formula weight	112699.07
Authors	Gayathri, P.,Banerjee, M.,Vijayalakshmi, A.,Balaram, H.,Balaram, P.,Murthy, M.R.N. (deposition date: 2007-11-04, release date: 2008-12-09, Last modification date: 2023-12-13)
Primary citation	Gayathri, P.,Banerjee, M.,Vijayalakshmi, A.,Balaram, H.,Balaram, P.,Murthy, M.R.N. Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site. Acta Crystallogr.,Sect.D, 65:847-, 2009 Cited by PubMed: 19622869 DOI: 10.1107/S0907444909018666 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation