2VFG
Crystal structure of the F96H mutant of Plasmodium falciparum triosephosphate isomerase with 3-phosphoglycerate bound at the dimer interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | TRIOSEPHOSPHATE ISOMERASE | polymer | 248 | 27988.7 | 4 | UniProt (Q07412) Pfam (PF00121) | PLASMODIUM FALCIPARUM (MALARIAL PARASITE) | TIM, TRIOSE-PHOSPHATE ISOMERASE |
| 2 | E, F, G, H (A, B, C, D) | 3-PHOSPHOGLYCERIC ACID | non-polymer | 186.1 | 4 | Chemie (3PG) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 677 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 248 (UniProt: Q07412)
| PDB | External Database | Details |
|---|---|---|
| His 96 | Phe 96 | engineered mutation |
| Val 163 | Ala 163 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 111954.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 744.2 | |
| All* | Total formula weight | 112699.1 |
