1M7O
Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog 3-phosphoglycerate (3PG)
Summary for 1M7O
| Entry DOI | 10.2210/pdb1m7o/pdb |
| Related | 1LYX 1LZO 1M7P 1YDV |
| Descriptor | Triosephosphate Isomerase, 3-PHOSPHOGLYCERIC ACID (3 entities in total) |
| Functional Keywords | tim barrels; beta-alpha barrels; enzyme-inhibitor complex, isomerase |
| Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
| Total number of polymer chains | 2 |
| Total formula weight | 56367.59 |
| Authors | Parthasarathy, S.,Balaram, H.,Balaram, P.,Murthy, M.R.N. (deposition date: 2002-07-22, release date: 2002-11-29, Last modification date: 2024-02-14) |
| Primary citation | Parthasarathy, S.,Balaram, H.,Balaram, P.,Murthy, M.R. Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state. Acta Crystallogr.,Sect.D, 58:1992-2000, 2002 Cited by PubMed: 12454456DOI: 10.1107/S0907444902015433 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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