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6UDN
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BU of 6udn by Molmil
Crystal Structure of a Self-Assembling DNA Scaffold Containing TA Sticky Ends and Rhombohedral Symmetry
Descriptor: ARSENIC, DNA (5'-D(*TP*AP*CP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*AP*TP*CP*AP*GP*AP*TP*G)-3'), ...
Authors:Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H.
Deposit date:2019-09-19
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail.
Angew.Chem.Int.Ed.Engl., 59, 2020
6U40
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BU of 6u40 by Molmil
Crystal Structure of a Self-Assembling DNA Crystal Scaffold with Rhombohedral Symmetry
Descriptor: CACODYLATE ION, DNA (5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*GP*AP*TP*G)-3'), ...
Authors:Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H.
Deposit date:2019-08-22
Release date:2020-08-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail.
Angew.Chem.Int.Ed.Engl., 59, 2020
6UEF
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BU of 6uef by Molmil
Crystal Structure of a Self-Assembling DNA Scaffold Containing Sequence Modifications to Attempt to Disrupt Crystal Contacts in a Rhombohedral Lattice.
Descriptor: DNA (5'-D(*CP*AP*AP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*GP*AP*TP*G)-3'), DNA (5'-D(P*AP*GP*CP*AP*TP*GP*A)-3'), ...
Authors:Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H.
Deposit date:2019-09-20
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail.
Angew.Chem.Int.Ed.Engl., 59, 2020
6V6R
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BU of 6v6r by Molmil
Crystal Structure of a Bromine Derivatized Self-Assembling DNA Crystal Scaffold with Rhombohedral Symmetry.
Descriptor: CACODYLATE ION, DNA (5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*GP*AP*TP*G)-3'), ...
Authors:Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H.
Deposit date:2019-12-05
Release date:2020-12-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail.
Angew.Chem.Int.Ed.Engl., 59, 2020
5U5S
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BU of 5u5s by Molmil
Solution structures of Brd2 second bromodomain in complex with stat3 peptide
Descriptor: Bromodomain-containing protein 2, Stat3 peptide
Authors:Zeng, L, Zhou, M.-M.
Deposit date:2016-12-07
Release date:2017-03-22
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.
Mol. Cell, 65, 2017
4LZU
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BU of 4lzu by Molmil
Bovine beta-lactoglobulin crystallized in the presence of 2 mM zinc chloride
Descriptor: Beta-lactoglobulin, ZINC ION
Authors:Oelker, M, Zocher, G, Stehle, T.
Deposit date:2013-08-01
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Non-Classical Pathways of Protein Crystallization in the Presence of Multivalent Metal Ions
To be Published
4LZV
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BU of 4lzv by Molmil
Bovine beta-lactoglobulin crystallized in the presence of 20 mM zinc chloride
Descriptor: Beta-lactoglobulin, ZINC ION
Authors:Oelker, M, Zocher, G, Stehle, T.
Deposit date:2013-08-01
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Non-Classical Pathways of Protein Crystallization in the Presence of Multivalent Metal Ions
To be Published
5KEO
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BU of 5keo by Molmil
Structure Determination of a Self-Assembling DNA Crystal
Descriptor: CACODYLATE ION, DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*AP*CP*AP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*TP*GP*T)-3'), ...
Authors:Simmons, C.R, Birktoft, J.J, Seeman, N.C, Yan, H.
Deposit date:2016-06-09
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Construction and Structure Determination of a Three-Dimensional DNA Crystal.
J.Am.Chem.Soc., 138, 2016
5KEK
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BU of 5kek by Molmil
Structure Determination of a Self-Assembling DNA Crystal
Descriptor: CACODYLATE ION, DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*AP*CP*AP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*TP*GP*T)-3'), ...
Authors:Simmons, C.R, Birktoft, J.J, Seeman, N.C, Yan, H.
Deposit date:2016-06-09
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.098 Å)
Cite:Construction and Structure Determination of a Three-Dimensional DNA Crystal.
J.Am.Chem.Soc., 138, 2016
2P39
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BU of 2p39 by Molmil
Crystal structure of human FGF23
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 23
Authors:Mohammadi, M.
Deposit date:2007-03-08
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
2P23
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BU of 2p23 by Molmil
Crystal structure of human FGF19
Descriptor: Fibroblast growth factor 19
Authors:Mohammadi, M.
Deposit date:2007-03-06
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
7BYM
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BU of 7bym by Molmil
Cryo-EM structure of human KCNQ4 with retigabine
Descriptor: Calmodulin-3, Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 4, POTASSIUM ION, ...
Authors:Shen, H, Li, T, Yue, Z.
Deposit date:2020-04-23
Release date:2020-12-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs.
Mol.Cell, 81, 2021
7BYL
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BU of 7byl by Molmil
Cryo-EM structure of human KCNQ4
Descriptor: Calmodulin-3, Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 4, POTASSIUM ION, ...
Authors:Shen, H, Li, T, Yue, Z.
Deposit date:2020-04-23
Release date:2020-12-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs.
Mol.Cell, 81, 2021
7BYN
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BU of 7byn by Molmil
Cryo-EM structure of human KCNQ4 with linopirdine
Descriptor: 1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one, Calmodulin-3, Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 4, ...
Authors:Shen, H, Li, T, Yue, Z.
Deposit date:2020-04-23
Release date:2020-12-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs.
Mol.Cell, 81, 2021
8TZ8
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BU of 8tz8 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT3 conformation
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ1
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BU of 8tz1 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Ribavirin
Descriptor: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ5
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BU of 8tz5 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with N-hydroxycytidine
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxycytidine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZD
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BU of 8tzd by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-OFS conformation (3DVA analysis)
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ2
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BU of 8tz2 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in MSP2N2 nanodiscs, apo state
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ6
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BU of 8tz6 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with PSI-6206
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2'-deoxy-2'-fluoro-2'-methyluridine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ9
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BU of 8tz9 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT2-INT2 conformation
Descriptor: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ3
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BU of 8tz3 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, consensus reconstruction
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.31 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZA
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BU of 8tza by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT1-INT1 conformation
Descriptor: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ4
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BU of 8tz4 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction
Descriptor: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ7
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BU of 8tz7 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT1 conformation
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024

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数据于2024-05-29公开中

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