25C8
 
 | | CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX | | Descriptor: | IGG 5C8, N-METHYL-N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM ION | | Authors: | Gruber, K, Wilson, I.A. | | Deposit date: | 1998-03-18 | | Release date: | 1999-03-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry, 38, 1999
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2CKB
 | | STRUCTURE OF THE 2C/KB/DEV8 COMPLEX | | Descriptor: | ALPHA, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ... | | Authors: | Garcia, K.C, Degano, M, Wilson, I.A. | | Deposit date: | 1998-01-14 | | Release date: | 1998-04-29 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.
Science, 279, 1998
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1ZHN
 | | Crystal Structure of mouse CD1d bound to the self ligand phosphatidylcholine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[(DODECANOYLOXY)METHYL]-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-3,5,8-TRIOXA-4-PHOSPHADOTRIACONTAN-1-AMINIUM 4-OXIDE, CD1d1 antigen, ... | | Authors: | Giabbai, B, Sidobre, S, Crispin, M.M.D, Sanchez Ruiz, Y, Bachi, A, Kronenberg, M, Wilson, I.A, Degano, M. | | Deposit date: | 2005-04-26 | | Release date: | 2005-07-19 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: a molecular basis for NKT cell activation
J.Immunol., 175, 2005
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4R26
 | | Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | | Descriptor: | GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain | | Authors: | Garces, F, Kong, L, Wilson, I.A. | | Deposit date: | 2014-08-08 | | Release date: | 2014-10-08 | | Last modified: | 2017-06-21 | | Method: | X-RAY DIFFRACTION (2.4969 Å) | | Cite: | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
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4R2G
 | | Crystal Structure of PGT124 Fab bound to HIV-1 JRCSF gp120 core and to CD4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Garces, F, Wilson, I.A. | | Deposit date: | 2014-08-11 | | Release date: | 2014-10-08 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.283 Å) | | Cite: | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
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2YMN
 | | Organization of the Influenza Virus Replication Machinery | | Descriptor: | NUCLEOPROTEIN | | Authors: | Moeller, A, Kirchdoerfer, R.N, Potter, C.S, Carragher, B, Wilson, I.A. | | Deposit date: | 2012-10-09 | | Release date: | 2012-12-05 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Organization of the Influenza Virus Replication Machinery.
Science, 338, 2012
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4RBP
 | | Crystal structure of HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomanose | | Descriptor: | Fab 2G12 heavy chain, Fab 2G12 light chain, GLYCEROL, ... | | Authors: | Stanfield, R.L, Wilson, I.A, De Castro, C, Marzaioli, A.M, Pantophlet, R. | | Deposit date: | 2014-09-12 | | Release date: | 2014-11-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose.
Glycobiology, 25, 2015
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4RQQ
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4RNR
 | | Crystal structure of broadly neutralizing anti-HIV antibody PGT130 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PGT130 Heavy Chain, PGT130 Light Chain | | Authors: | Kong, L, Wilson, I.A. | | Deposit date: | 2014-10-24 | | Release date: | 2014-11-19 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.758 Å) | | Cite: | Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.
J.Virol., 89, 2015
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4RQS
 | | Crystal structure of fully glycosylated HIV-1 gp120 core bound to CD4 and 17b Fab | | Descriptor: | 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kong, L, Wilson, I.A, Kwong, P.D. | | Deposit date: | 2014-11-05 | | Release date: | 2014-12-31 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (4.493 Å) | | Cite: | Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
Proteins, 83, 2015
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6PBW
 | | Crystal structure of Fab667 complex | | Descriptor: | Fab667 heavy chain, Fab667 light chain, GLYCEROL, ... | | Authors: | Oyen, D, Wilson, I.A. | | Deposit date: | 2019-06-14 | | Release date: | 2020-03-04 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.058 Å) | | Cite: | Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
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6PBV
 | | Crystal structure of Fab668 complex | | Descriptor: | 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ... | | Authors: | Oyen, D, Wilson, I.A. | | Deposit date: | 2019-06-14 | | Release date: | 2020-03-04 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.566 Å) | | Cite: | Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
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6Q1Z
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6PZD
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6PZE
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6PZF
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6PZG
 | | Crystal structure of human NA-80 Fab | | Descriptor: | NA-80 Fab heavy chain, NA-80 Fab light chain | | Authors: | Zhu, X, Wilson, I.A. | | Deposit date: | 2019-07-31 | | Release date: | 2019-12-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
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6Q23
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6PZH
 | | Crystal structure of human NA-22 Fab | | Descriptor: | NA-22 Fab heavy chain, NA-22 Fab light chain | | Authors: | Zhu, X, Wilson, I.A. | | Deposit date: | 2019-07-31 | | Release date: | 2019-12-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
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6Q20
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6TZB
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6UC5
 | | Fab397 in complex with NPNA peptide | | Descriptor: | Fab397 heavy chain, Fab397 light chain, NPNA peptide | | Authors: | Pholcharee, T, Oyen, D, Wilson, I.A. | | Deposit date: | 2019-09-13 | | Release date: | 2020-01-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein.
J.Mol.Biol., 432, 2020
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2PRT
 | | Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA | | Descriptor: | DNA (5'-D(*CP*AP*GP*AP*CP*GP*CP*CP*CP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*GP*GP*GP*CP*GP*TP*CP*TP*G)-3'), Wilms tumor 1, ... | | Authors: | Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2007-05-04 | | Release date: | 2008-03-04 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
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2QGE
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2QGD
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