3TED
 
 | | Crystal structure of the Chd1 DNA-binding domain in complex with a DNA duplex | | Descriptor: | 5'-D(*CP*CP*AP*TP*AP*TP*AP*TP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*AP*TP*AP*TP*AP*TP*GP*G)-3', Chromo domain-containing protein 1 | | Authors: | Sharma, A, Jenkins, K.R, Heroux, A, Bowman, G.D. | | Deposit date: | 2011-08-12 | | Release date: | 2011-11-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | DNA-binding domain of Chd1 in complex with a DNA duplex
J.Biol.Chem., 2011
|
|
4ZVJ
 | | Structure of human triose phosphate isomerase K13M | | Descriptor: | POTASSIUM ION, SODIUM ION, Triosephosphate isomerase | | Authors: | Amrich, C.G, Smith, C, Heroux, A, VanDemark, A.P. | | Deposit date: | 2015-05-18 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.6996 Å) | | Cite: | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim. Biophys. Acta, 1852, 2015
|
|
1YWM
 | | Crystal structure of the N-terminal domain of group B Streptococcus alpha C protein | | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, C protein alpha-antigen, GLYCEROL | | Authors: | Auperin, T.C, Bolduc, G.R, Baron, M.J, Heroux, A, Filman, D.J, Madoff, L.C, Hogle, J.M. | | Deposit date: | 2005-02-18 | | Release date: | 2005-03-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Crystal structure of the N-terminal domain of the group B streptococcus alpha C protein.
J.Biol.Chem., 280, 2005
|
|
2R0S
 | | Crystal Structure of the Rsc4 tandem bromodomain | | Descriptor: | Chromatin structure-remodeling complex protein RSC4 | | Authors: | VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R. | | Deposit date: | 2007-08-21 | | Release date: | 2007-10-30 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
|
|
2R3C
 | | Structure of the gp41 N-peptide in complex with the HIV entry inhibitor PIE1 | | Descriptor: | CHLORIDE ION, HIV entry inhibitor PIE1, YTTRIUM (III) ION, ... | | Authors: | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | Deposit date: | 2007-08-29 | | Release date: | 2007-10-02 | | Last modified: | 2018-08-08 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2RF3
 | | Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles | | Descriptor: | 5'-d(CGCG(TCY)ATTCGCG)-3', SPERMINE, ZINC ION | | Authors: | Pallan, P.S, Ittig, D, Heroux, A, Wawrzak, Z, Leumann, C.J, Egli, M. | | Deposit date: | 2007-09-27 | | Release date: | 2008-02-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles.
Chem.Commun.(Camb.), 2008, 2008
|
|
4PZ2
 | | Structure of Zm ALDH2-6 (RF2F) in complex with NAD | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Morera, S, Vigouroux, A, Kopecny, D. | | Deposit date: | 2014-03-28 | | Release date: | 2015-03-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Role and structural characterization of plant aldehyde dehydrogenases from family 2 and family 7.
Biochem.J., 468, 2015
|
|
4PXL
 | | Structure of Zm ALDH2-3 (RF2C) in complex with NAD | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cytosolic aldehyde dehydrogenase RF2C, ... | | Authors: | Morera, S, Vigouroux, A, Kopecny, D. | | Deposit date: | 2014-03-24 | | Release date: | 2015-03-18 | | Last modified: | 2015-05-20 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Role and structural characterization of plant aldehyde dehydrogenases from family 2 and family 7.
Biochem.J., 468, 2015
|
|
1R7S
 | | PUTIDAREDOXIN (Fe2S2 ferredoxin), C73G mutant | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, Putidaredoxin | | Authors: | Smith, N, Mayhew, M, Kelly, H, Robinson, H, Heroux, A, Holden, M.J, Gallagher, D.T. | | Deposit date: | 2003-10-22 | | Release date: | 2004-04-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structure of C73G putidaredoxin from Pseudomonas putida.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
4R0X
 | | Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5 | | Authors: | LeMaster, D.M, Mustafi, S.M, Brecher, M, Zhang, J, Heroux, A, Li, H.M, Hernandez, G. | | Deposit date: | 2014-08-02 | | Release date: | 2015-05-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins.
J.Biol.Chem., 290, 2015
|
|
4POC
 | | Structure of Triosephosphate Isomerase Wild Type human enzyme. | | Descriptor: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | | Deposit date: | 2014-02-25 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
|
|
4POD
 | | Structure of Triosephosphate Isomerase I170V mutant human enzyme. | | Descriptor: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | | Deposit date: | 2014-02-25 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
|
|
2VF1
 | | X-ray crystallographic structure of the picobirnavirus capsid | | Descriptor: | CAPSID PROTEIN | | Authors: | Duquerroy, S, Da Costa, B, Vigouroux, A, Lepault, J, Navaza, J, Delmas, B, Rey, F.A. | | Deposit date: | 2007-10-29 | | Release date: | 2008-12-16 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | The Picobirnavirus Crystal Structure Provides Functional Insights Into Virion Assembly and Cell Entry.
Embo J., 28, 2009
|
|
2R5B
 | | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | | Descriptor: | HIV entry inhibitor PIE7, SULFATE ION, gp41 N-peptide | | Authors: | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | Deposit date: | 2007-09-03 | | Release date: | 2007-10-02 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2R5D
 | | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HIV entry inhibitor PIE7, ... | | Authors: | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | | Deposit date: | 2007-09-03 | | Release date: | 2007-10-02 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Potent D-peptide inhibitors of HIV-1 entry
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
4PXN
 | | Structure of Zm ALDH7 in complex with NAD | | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Uncharacterized protein | | Authors: | Morera, S, Vigouroux, A, Kopecny, D. | | Deposit date: | 2014-03-24 | | Release date: | 2015-03-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Role and structural characterization of plant aldehyde dehydrogenases from family 2 and family 7.
Biochem.J., 468, 2015
|
|
4GDX
 | | Crystal Structure of Human Gamma-Glutamyl Transpeptidase--Glutamate complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLUTAMIC ACID, ... | | Authors: | West, M.B, Chen, Y, Wickham, S, Heroux, A, Cahill, K, Hanigan, M.H, Mooers, B.H.M. | | Deposit date: | 2012-08-01 | | Release date: | 2013-09-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme.
J.Biol.Chem., 288, 2013
|
|
4HMJ
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS L36D at cryogenic temperature | | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | Authors: | Robinson, A.C, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | | Deposit date: | 2012-10-18 | | Release date: | 2012-10-31 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS L36D at cryogenic temperature
To be Published
|
|
4I8P
 | | Crystal structure of aminoaldehyde dehydrogenase 1a from Zea mays (ZmAMADH1a) | | Descriptor: | 1,2-ETHANEDIOL, Aminoaldehyde dehydrogenase 1, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Morera, S, Vigouroux, A, Kopecny, D. | | Deposit date: | 2012-12-04 | | Release date: | 2013-02-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Plant ALDH10 family: identifying critical residues for substrate specificity and trapping a thiohemiacetal intermediate.
J.Biol.Chem., 288, 2013
|
|
4I8Q
 | | Structure of the aminoaldehyde dehydrogenase 1 E260A mutant from Solanum lycopersicum (SlAMADH1-E260A) | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Morera, S, Vigouroux, A, Kopecny, D. | | Deposit date: | 2012-12-04 | | Release date: | 2013-02-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Plant ALDH10 family: identifying critical residues for substrate specificity and trapping a thiohemiacetal intermediate.
J.Biol.Chem., 288, 2013
|
|
4I9B
 | | Structure of aminoaldehyde dehydrogenase 1 from Solanum lycopersium (SlAMADH1) with a thiohemiacetal intermediate | | Descriptor: | (2-hydroxyethoxy)acetaldehyde, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Morera, S, Vigouroux, A, Kopecny, D. | | Deposit date: | 2012-12-05 | | Release date: | 2013-02-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Plant ALDH10 family: identifying critical residues for substrate specificity and trapping a thiohemiacetal intermediate.
J.Biol.Chem., 288, 2013
|
|
4J2N
 | | Crystal Structure of mycobacteriophage Pukovnik Xis | | Descriptor: | Gp37, SULFATE ION | | Authors: | Homa, N.J, Amrich, C.G, Heroux, A, VanDemark, A.P. | | Deposit date: | 2013-02-04 | | Release date: | 2013-10-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.348 Å) | | Cite: | The Structure of Xis Reveals the Basis for Filament Formation and Insight into DNA Bending within a Mycobacteriophage Intasome.
J.Mol.Biol., 426, 2014
|
|
4GG2
 | | The crystal structure of glutamate-bound human gamma-glutamyltranspeptidase 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLUTAMIC ACID, ... | | Authors: | West, M.B, Chen, Y, Wickham, S, Heroux, A, Cahill, K, Hanigan, M.H, Mooers, B.H.M. | | Deposit date: | 2012-08-04 | | Release date: | 2013-09-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme.
J.Biol.Chem., 288, 2013
|
|
4L1P
 | |
4L2M
 | | Crystal structure of the 2/2 hemoglobin from Synechococcus sp. PCC 7002 in the cyanomet state and with covalently attached heme | | Descriptor: | CYANIDE ION, Cyanoglobin, HEME B/C, ... | | Authors: | Wenke, B.B, Schlessman, J.L, Heroux, A, Lecomte, J.T.J. | | Deposit date: | 2013-06-04 | | Release date: | 2013-06-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The 2/2 hemoglobin from the cyanobacterium Synechococcus sp. PCC 7002 with covalently attached heme: Comparison of X-ray and NMR structures.
Proteins, 82, 2014
|
|
