3U61
| Structure of T4 Bacteriophage Clamp Loader Bound To Closed Clamp, DNA and ATP Analog and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | Deposit date: | 2011-10-11 | Release date: | 2012-01-04 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
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3U60
| Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | Deposit date: | 2011-10-11 | Release date: | 2012-01-04 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
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1AQC
| X11 PTB DOMAIN-10MER PEPTIDE COMPLEX | Descriptor: | PEPTIDE, X11 | Authors: | Lee, C.-H, Zhang, Z, Kuriyan, J. | Deposit date: | 1997-07-28 | Release date: | 1997-12-24 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. EMBO J., 16, 1997
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1NVX
| Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J. | Deposit date: | 2003-02-04 | Release date: | 2003-04-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS Cell(Cambridge,Mass.), 112, 2003
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1NVW
| Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J. | Deposit date: | 2003-02-04 | Release date: | 2003-04-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS Cell(Cambridge,Mass.), 112, 2003
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1Q9C
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1QQC
| CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK | Descriptor: | DNA POLYMERASE II, MAGNESIUM ION, SULFATE ION | Authors: | Zhao, Y, Jeruzalmi, D, Leighton, L, Lasken, R, Kuriyan, J. | Deposit date: | 1999-06-02 | Release date: | 1999-10-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of an archaebacterial DNA polymerase Structure Fold.Des., 7, 1999
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1NVU
| Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J. | Deposit date: | 2003-02-04 | Release date: | 2003-04-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS Cell(Cambridge,Mass.), 112, 2003
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1NVV
| Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J. | Deposit date: | 2003-02-04 | Release date: | 2003-04-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structural evidence for feedback activation by RasGTP of the
Ras-specific nucleotide exchange factor SOS Cell(Cambridge,Mass.), 112, 2003
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1B6C
| CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE TYPE I TGF-BETA RECEPTOR IN COMPLEX WITH FKBP12 | Descriptor: | FK506-BINDING PROTEIN, SULFATE ION, TGF-B SUPERFAMILY RECEPTOR TYPE I | Authors: | Huse, M, Chen, Y.-G, Massague, J, Kuriyan, J. | Deposit date: | 1999-01-13 | Release date: | 1999-06-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell(Cambridge,Mass.), 96, 1999
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1AXC
| HUMAN PCNA | Descriptor: | P21/WAF1, PCNA | Authors: | Gulbis, J.M, Kuriyan, J. | Deposit date: | 1997-10-14 | Release date: | 1998-01-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Cell(Cambridge,Mass.), 87, 1996
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1QCF
| CRYSTAL STRUCTURE OF HCK IN COMPLEX WITH A SRC FAMILY-SELECTIVE TYROSINE KINASE INHIBITOR | Descriptor: | 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, Tyrosine-protein kinase HCK | Authors: | Schindler, T, Sicheri, F, Pico, A, Gazit, A, Levitzki, A, Kuriyan, J. | Deposit date: | 1999-05-04 | Release date: | 1999-06-08 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor. Mol.Cell, 3, 1999
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1SPS
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1SHB
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1SHA
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1U56
| Crystal structure of an oxygen binding H-NOX domain related to soluble guanylate cyclases (Water-ligated, ferric form) | Descriptor: | CHLORIDE ION, Heme-based Methyl-accepting chemotaxis protein, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Pellicena, P, Karow, D.S, Boon, E.M, Marletta, M.A, Kuriyan, J. | Deposit date: | 2004-07-27 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases. Proc.Natl.Acad.Sci.Usa, 101, 2004
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1U4H
| Crystal structure of an oxygen binding H-NOX domain related to soluble guanylate cyclases (oxygen complex) | Descriptor: | GLYCEROL, Heme-based Methyl-accepting Chemotaxis Protein, OXYGEN MOLECULE, ... | Authors: | Pellicena, P, Karow, D.S, Boon, E.M, Marletta, M.A, Kuriyan, J. | Deposit date: | 2004-07-25 | Release date: | 2004-08-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases. Proc.Natl.Acad.Sci.Usa, 101, 2004
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1U55
| Crystal structure of an oxygen binding H-NOX domain related to soluble guanylate cyclases (oxygen complex) | Descriptor: | CHLORIDE ION, Heme-based Methyl-accepting Chemotaxis Protein, OXYGEN MOLECULE, ... | Authors: | Pellicena, P, Karow, D.S, Boon, E.M, Marletta, M.A, Kuriyan, J. | Deposit date: | 2004-07-27 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases. Proc.Natl.Acad.Sci.Usa, 101, 2004
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1FJM
| Protein serine/threonine phosphatase-1 (alpha isoform, type 1) complexed with microcystin-LR toxin | Descriptor: | BETA-MERCAPTOETHANOL, MANGANESE (II) ION, PROTEIN SERINE/THREONINE PHOSPHATASE-1 (ALPHA ISOFORM, ... | Authors: | Goldberg, J, Nairn, A.C, Kuriyan, J. | Deposit date: | 1995-12-17 | Release date: | 1996-06-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1. Nature, 376, 1995
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1EM8
| Crystal structure of chi and psi subunit heterodimer from DNA POL III | Descriptor: | DNA POLYMERASE III CHI SUBUNIT, DNA POLYMERASE III PSI SUBUNIT | Authors: | Gulbis, J.M, Finkelstein, J, O'Donnell, M, Kuriyan, J. | Deposit date: | 2000-03-16 | Release date: | 2003-08-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the chi:psi sub-assembly of the Escherichia coli DNA polymerase clamp-loader complex. Eur.J.Biochem., 271, 2004
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1SXJ
| Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Activator 1 37 kDa subunit, Activator 1 40 kDa subunit, ... | Authors: | Bowman, G.D, O'Donnell, M, Kuriyan, J. | Deposit date: | 2004-03-30 | Release date: | 2004-06-22 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex. Nature, 429, 2004
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1IAS
| CYTOPLASMIC DOMAIN OF UNPHOSPHORYLATED TYPE I TGF-BETA RECEPTOR CRYSTALLIZED WITHOUT FKBP12 | Descriptor: | SULFATE ION, TGF-BETA RECEPTOR TYPE I | Authors: | Huse, M, Muir, T.W, Chen, Y.-G, Kuriyan, J, Massague, J. | Deposit date: | 2001-03-23 | Release date: | 2001-10-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The TGF beta receptor activation process: an inhibitor- to substrate-binding switch. Mol.Cell, 8, 2001
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1EQN
| E.COLI PRIMASE CATALYTIC CORE | Descriptor: | DNA PRIMASE | Authors: | Podobnik, M, McInerney, P, O'Donnell, M, Kuriyan, J. | Deposit date: | 2000-04-05 | Release date: | 2000-06-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases. J.Mol.Biol., 300, 2000
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1FPU
| CRYSTAL STRUCTURE OF ABL KINASE DOMAIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR | Descriptor: | N-[4-METHYL-3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-3-PYRIDINECARBOXAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL | Authors: | Schindler, T, Bornmann, W, Pellicena, P, Miller, W.T, Clarkson, B, Kuriyan, J. | Deposit date: | 2000-08-31 | Release date: | 2000-09-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural mechanism for STI-571 inhibition of abelson tyrosine kinase. Science, 289, 2000
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1BGF
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