1SXJ

Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)

Summary for 1SXJ

• Entry DOI: 10.2210/pdb1sxj/pdb
• Related: 1PLQ
• Descriptor: Activator 1 95 kDa subunit, Activator 1 37 kDa subunit, Activator 1 40 kDa subunit, ... (9 entities in total)
• Functional Keywords: clamp loader, processivity clamp, dna sliding clamp, aaa+ atpase, dna polymerase, dna-binding protein, replication
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Cellular location: Nucleus (Probable): P38630 P40339 P38629 P40348 P38251; Nucleus: P15873
• Total number of polymer chains: 8
• Total formula weight: 309282.41

Authors

Bowman, G.D.,O'Donnell, M.,Kuriyan, J. (deposition date: 2004-03-30, release date: 2004-06-22, Last modification date: 2023-11-15)

• Primary citation: Bowman, G.D.,O'Donnell, M.,Kuriyan, J.; Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.; Nature, 429:724-730, 2004; PubMed: 15201901; DOI: 10.1038/nature02585

Experimental method

X-RAY DIFFRACTION (2.85 Å)