2ASY
| Solution Structure of ydhR protein from Escherichia coli | Descriptor: | Protein ydhR precursor | Authors: | Revington, M, Semesi, A, Yee, A, Shaw, G.S, Ontario Centre for Structural Proteomics (OCSP) | Deposit date: | 2005-08-24 | Release date: | 2005-11-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the Escherichia coli protein ydhR: A putative mono-oxygenase. Protein Sci., 14, 2005
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2X8G
| Oxidized thioredoxin glutathione reductase from Schistosoma mansoni | Descriptor: | DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Angelucci, F, Dimastrogiovanni, D, Boumis, G, Brunori, M, Miele, A.E, Saccoccia, F, Bellelli, A. | Deposit date: | 2010-03-09 | Release date: | 2010-07-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mapping the Catalytic Cycle of Schistosoma Mansoni Thioredoxin Glutathione Reductase by X-Ray Crystallography J.Biol.Chem., 285, 2010
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5DL5
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2AX4
| Crystal structure of the kinase domain of human 3'-phosphoadenosine 5'-phosphosulphate synthetase 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 | Authors: | Rabeh, W.M, Nedyalkova, L, Ismail, S, Park, H, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Structural Genomics Consortium (SGC) | Deposit date: | 2005-09-02 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the kinase domain of PAPSS 2 To be Published
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2AXK
| Solution structure of discrepin, a scorpion venom toxin blocking K+ channels. | Descriptor: | discrepin | Authors: | Prochnicka-Chalufour, A, Corzo, G, Satake, H, Martin-Eauclaire, M.-F, Murgia, A.R, Prestipino, G, D'Suze, G, Possani, L.D, Delepierre, M. | Deposit date: | 2005-09-05 | Release date: | 2006-06-20 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily. Biochemistry, 45, 2006
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6R1T
| Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome | Descriptor: | DNA (147-MER), HISTONE H2A, Histone H2A, ... | Authors: | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | Deposit date: | 2019-03-15 | Release date: | 2019-04-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.02 Å) | Cite: | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
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1O17
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6R1U
| Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2 | Descriptor: | DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A, ... | Authors: | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | Deposit date: | 2019-03-15 | Release date: | 2019-04-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.36 Å) | Cite: | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
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5FCS
| Diabody | Descriptor: | Diabody, SULFATE ION | Authors: | Mosyak, L, Root, A. | Deposit date: | 2015-12-15 | Release date: | 2016-12-14 | Last modified: | 2019-11-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer. Antibodies, 5, 2016
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6RBK
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5DS1
| Core domain of the class II small heat-shock protein HSP 17.7 from Pisum sativum | Descriptor: | 17.1 kDa class II heat shock protein | Authors: | Hochberg, G.K.A, Laganoswky, A, Allison, T.A, Shepherd, D.A, Benesch, J.L.P. | Deposit date: | 2015-09-16 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions. Science, 359, 2018
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6R25
| Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3 | Descriptor: | DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, H2B, ... | Authors: | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | Deposit date: | 2019-03-15 | Release date: | 2019-04-24 | Method: | ELECTRON MICROSCOPY (4.61 Å) | Cite: | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
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2AI0
| Anti-Cocaine Antibody 7.5.21, Crystal Form III | Descriptor: | GLYCEROL, Immunoglobulin Heavy Chain, Immunoglobulin Light Chain kappa, ... | Authors: | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | Deposit date: | 2005-07-28 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Flexibility of Packing: Four Crystal Forms of an Anti-Cocaine Antibody 7.5.21 To be Published
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6GUY
| Room temperature structure of Archaerhodopsin-3 via LCP extruder using synchrotron radiation | Descriptor: | Archaerhodopsin-3, CALCIUM ION, CHLORIDE ION, ... | Authors: | Moraes, I, Judge, P.J, Axford, D, Bada Juarez, J.F, Vinals, J, Watts, A. | Deposit date: | 2018-06-19 | Release date: | 2019-10-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Room temperature structure of Archaerhodopsin-3 via LCP extruder using synchrotron radiation To Be Published
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3T1W
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6R7F
| Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | Descriptor: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | Authors: | Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. | Deposit date: | 2019-03-28 | Release date: | 2019-08-28 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
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1O6H
| Squalene-Hopene Cyclase | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, N-(6-{[1-(4-BROMOPHENYL)ISOQUINOLIN-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE, SQUALENE--HOPENE CYCLASE | Authors: | Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E. | Deposit date: | 2002-10-03 | Release date: | 2003-10-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase J.Med.Chem., 46, 2003
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1O79
| Structures of human oxidosqualene cyclase inhibitors bound to an homologous enzyme | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, METHYL-[4-(4-PIPERIDINE-1-YLMETHYL-PHENYL)-CYCLOHEXYL]-CARBAMINIC ACID-(4-CHLOROPHENYL)-ESTER, SQUALENE--HOPENE CYCLASE | Authors: | Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E. | Deposit date: | 2002-10-27 | Release date: | 2003-10-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase J.Med.Chem., 46, 2003
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1O6Q
| Structures of human oxidosqualene cyclase inhibitors bound to an homologous enzyme | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ALLYL-{4-[3-(4-BROMO-PHENYL)-BENZOFURAN-6-YLOXY]-BUT-2-ENYL}-METHYL-AMINE, SQUALENE--HOPENE CYCLASE | Authors: | Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E. | Deposit date: | 2002-10-13 | Release date: | 2003-10-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase J.Med.Chem., 46, 2003
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3GV6
| Crystal Structure of human chromobox homolog 6 (CBX6) with H3K9 peptide | Descriptor: | Chromobox protein homolog 6, Histone H3K9me3 peptide | Authors: | Dong, A, Amaya, M.F, Li, Z, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-03-30 | Release date: | 2009-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
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1O6R
| Structures of human oxidosqualene cyclase inhibitors bound to an homologous enzyme | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ALLYL-{6-[3-(4-BROMO-PHENYL)-BENZOFURAN-6-YLOXY]-HEXYL-}-METHYL-AMIN, SQUALENE--HOPENE CYCLASE | Authors: | Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E. | Deposit date: | 2002-10-13 | Release date: | 2003-10-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase J.Med.Chem., 46, 2003
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3T5F
| Human Thrombin In Complex With MI340 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hirudin variant-2, ... | Authors: | Biela, A, Heine, A, Klebe, G. | Deposit date: | 2011-07-27 | Release date: | 2012-08-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Ligand binding stepwise disrupts water network in thrombin: enthalpic and entropic changes reveal classical hydrophobic effect J.Med.Chem., 55, 2012
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5EAQ
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1NRN
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3T8G
| Thermolysin In Complex With UBTLN26 | Descriptor: | CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Biela, A, Heine, A, Klebe, G. | Deposit date: | 2011-08-01 | Release date: | 2012-08-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Water makes the difference: rearrangement of water solvation layer triggers non-additivity of functional group contributions in protein-ligand binding. Chemmedchem, 7, 2012
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