3KV7
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![BU of 3kv7 by Molmil](/molmil-images/mine/3kv7) | Structural basis of the activity and substrate specificity of the fluoroacetyl-CoA thioesterase FlK - wild type FlK in complex with acetate | Descriptor: | ACETATE ION, fluoroacetyl-CoA thioesterase FlK | Authors: | Dias, M.V.B, Huang, F, Chirgadze, D.Y, Tosin, M, Spiteller, D, Valentine, E.F, Leadlay, P.F, Spencer, J.B, Blundell, T.L. | Deposit date: | 2009-11-29 | Release date: | 2010-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK. J.Biol.Chem., 285, 2010
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4AMG
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![BU of 4amg by Molmil](/molmil-images/mine/4amg) | Crystal structure of the glycosyltransferase SnogD from Streptomyces nogalater | Descriptor: | SNOGD | Authors: | Claesson, M, Siitonen, V, Dobritzsch, D, Metsa-Ketela, M, Schneider, G. | Deposit date: | 2012-03-09 | Release date: | 2012-09-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal Structure of the Glycosyltransferase Snogd from the Biosynthetic Pathway of the Nogalamycin in Streptomyces Nogalater. FEBS J., 279, 2012
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3KFT
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![BU of 3kft by Molmil](/molmil-images/mine/3kft) | Crystal structure of Pentaerythritol Tetranitrate Reductase complex with 1,4,5,6-tetrahydro NADH | Descriptor: | FLAVIN MONONUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pentaerythritol tetranitrate reductase | Authors: | Pudney, C.R, Levy, C.W, Leys, D, Scrutton, N.S. | Deposit date: | 2009-10-28 | Release date: | 2010-02-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction. J.Am.Chem.Soc., 131, 2009
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4AOW
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![BU of 4aow by Molmil](/molmil-images/mine/4aow) | Crystal structure of the human Rack1 protein at a resolution of 2.45 angstrom | Descriptor: | GLYCEROL, GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-2-LIKE 1 | Authors: | Ruiz Carrillo, D, Chandrasekaran, R, Nilsson, M, Cornvick, T, Liew, C.W, Tan, S.M, Lescar, J. | Deposit date: | 2012-03-30 | Release date: | 2012-08-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of Human Rack1 Protein at a Resolution of 2.45 A. Acta Crystallogr.,Sect.F, 68, 2012
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3E9F
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![BU of 3e9f by Molmil](/molmil-images/mine/3e9f) | Crystal structure short-form (residue1-113) of Eaf3 chromo domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Chromatin modification-related protein EAF3 | Authors: | Sun, B, Hong, J, Zhang, P, Lin, D, Ding, J. | Deposit date: | 2008-08-22 | Release date: | 2008-11-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36 J.Biol.Chem., 283, 2008
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2OYN
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![BU of 2oyn by Molmil](/molmil-images/mine/2oyn) | Crystal structure of CDP-bound protein MJ0056 from Methanococcus jannaschii, Pfam DUF120 | Descriptor: | CYTIDINE-5'-DIPHOSPHATE, Hypothetical protein MJ0056, SODIUM ION | Authors: | Bonanno, J.B, Dickey, M, Bain, K.T, Lau, C, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-02-22 | Release date: | 2007-03-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of hypothetical protein from Methanococcus jannaschii bound to CDP TO BE PUBLISHED
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1GJZ
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3EBA
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![BU of 3eba by Molmil](/molmil-images/mine/3eba) | CAbHul6 FGLW mutant (humanized) in complex with human lysozyme | Descriptor: | CAbHul6, Lysozyme C, SULFATE ION | Authors: | Loris, R, Vincke, C, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | Deposit date: | 2008-08-27 | Release date: | 2008-12-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold J.Biol.Chem., 284, 2009
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4AJM
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![BU of 4ajm by Molmil](/molmil-images/mine/4ajm) | Development of a plate-based optical biosensor methodology to identify PDE10 fragment inhibitors | Descriptor: | 3-AMINO-6-FLUORO-2-[4-(2-METHYLPYRIDIN-4-YL)PHENYL]-N-(METHYLSULFONYL)QUINOLINE-4-CARBOXAMIDE, CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE 10A, ... | Authors: | Geschwindner, S, Johansson, P, Spadola, L, Akerud, T, Back, E, Hillertz, P, Horsefeld, R, Scott, C, Spear, N, Tian, G, Tigerstrom, A, Aharony, D, Albert, J.S. | Deposit date: | 2012-02-16 | Release date: | 2013-03-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Development of a Plate-Based Optical Biosensor Methodology to Identify Pde10 Fragment Inhibitors To be Published
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3KJM
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4ABX
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![BU of 4abx by Molmil](/molmil-images/mine/4abx) | Crystal structure of Deinococcus radiodurans RecN coiled-coil domain | Descriptor: | DNA REPAIR PROTEIN RECN | Authors: | Pellegrino, S, Radzimanowski, J, de Sanctis, D, McSweeney, S, Timmins, J. | Deposit date: | 2011-12-12 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.041 Å) | Cite: | Structural and Functional Characterization of an Smc-Like Protein Recn: New Insights Into Double-Strand Break Repair. Structure, 20, 2012
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3ELX
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![BU of 3elx by Molmil](/molmil-images/mine/3elx) | Crystal structure of apo Zebrafish Ileal Bile Acid-Binding Protein | Descriptor: | 1,2-ETHANEDIOL, Ileal bile acid-binding protein | Authors: | Capaldi, S, Saccomani, G, Fessas, D, Signorelli, M, Perduca, M, Monaco, H.L. | Deposit date: | 2008-09-23 | Release date: | 2009-01-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The X-Ray structure of zebrafish (Danio rerio) ileal bile acid-binding protein reveals the presence of binding sites on the surface of the protein molecule. J.Mol.Biol., 385, 2009
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3KLA
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![BU of 3kla by Molmil](/molmil-images/mine/3kla) | Ca2+ release from the endoplasmic reticulum of NY-ESO-1 specific T cells is modulated by the affinity of T cell receptor and by the use of the CD8 co-receptor | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Chen, J.L, Morgan, A.J, Stewart-Jones, G, Shepherd, D, Bossi, G, Wooldridge, L. | Deposit date: | 2009-11-07 | Release date: | 2010-02-16 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Ca2+ Release from the Endoplasmic Reticulum of NY-ESO-1-Specific T Cells Is Modulated by the Affinity of TCR and by the Use of the CD8 Coreceptor. J.Immunol., 184, 2010
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4AGH
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![BU of 4agh by Molmil](/molmil-images/mine/4agh) | Structural features of ssDNA binding protein MoSub1 from Magnaporthe oryzae | Descriptor: | MOSUB1, TRANSCRIPTION COFACTOR | Authors: | Huang, J, Zhao, Y, Huang, D, liu, J, Peng, Y. | Deposit date: | 2012-01-27 | Release date: | 2012-08-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.787 Å) | Cite: | Structural Features of the Single-Stranded DNA-Binding Protein Mosub1 from Magnaporthe Oryzae. Acta Crystallogr.,Sect.D, 68, 2012
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4A95
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![BU of 4a95 by Molmil](/molmil-images/mine/4a95) | Plasmodium vivax N-myristoyltransferase with quinoline inhibitor | Descriptor: | 2-oxopentadecyl-CoA, 3-(3-BUTYL-6-METHOXY-2-METHYL-QUINOLIN-4-YL)SULFANYLPROPANENITRILE, CHLORIDE ION, ... | Authors: | Goncalves, V, Brannigan, J.A, Whalley, D, Ansell, K.H, Saxty, B, Holder, A.A, Wilkinson, A.J, Tate, E.W, Leatherbarrow, R.J. | Deposit date: | 2011-11-24 | Release date: | 2012-06-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Discovery of Plasmodium Vivax N-Myristoyltransferase Inhibitors: Screening, Synthesis, and Structural Characterization of Their Binding Mode. J.Med.Chem., 55, 2012
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1GPJ
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![BU of 1gpj by Molmil](/molmil-images/mine/1gpj) | Glutamyl-tRNA Reductase from Methanopyrus kandleri | Descriptor: | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, CITRIC ACID, GLUTAMIC ACID, ... | Authors: | Moser, J, Schubert, W.-D, Beier, V, Bringemeier, I, Jahn, D, Heinz, D.W. | Deposit date: | 2001-11-05 | Release date: | 2002-01-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | V-shaped structure of glutamyl-tRNA reductase, the first enzyme of tRNA-dependent tetrapyrrole biosynthesis. EMBO J., 20, 2001
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1GUW
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![BU of 1guw by Molmil](/molmil-images/mine/1guw) | STRUCTURE OF THE CHROMODOMAIN FROM MOUSE HP1beta IN COMPLEX WITH THE LYSINE 9-METHYL HISTONE H3 N-TERMINAL PEPTIDE, NMR, 25 STRUCTURES | Descriptor: | CHROMOBOX PROTEIN HOMOLOG 1, HISTONE H3.1 | Authors: | Nielsen, P.R, Nietlispach, D, Mott, H.R, Callaghan, J.M, Bannister, A, Kouzarides, T, Murzin, A.G, Murzina, N.V, Laue, E.D. | Deposit date: | 2002-02-01 | Release date: | 2002-03-12 | Last modified: | 2018-01-17 | Method: | SOLUTION NMR | Cite: | Structure of the Hp1 Chromodomain Bound to Histone H3 Methylated at Lysine 9 Nature, 416, 2002
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3KOY
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![BU of 3koy by Molmil](/molmil-images/mine/3koy) | Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic) | Descriptor: | (E)-N~5~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-ornithine, 5'-DEOXYADENOSINE, COBALAMIN, ... | Authors: | Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. | Deposit date: | 2009-11-14 | Release date: | 2010-01-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
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1GYE
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![BU of 1gye by Molmil](/molmil-images/mine/1gye) | Structure of Cellvibrio cellulosa alpha-L-arabinanase complexed with Arabinohexaose | Descriptor: | ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A, CHLORIDE ION, alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose | Authors: | Nurizzo, D, Turkenburg, J.P, Charnock, S.J, Roberts, S.M, Dodson, E.J, McKie, V.A, Taylor, E.J, Gilbert, H.J, Davies, G.J. | Deposit date: | 2002-04-23 | Release date: | 2002-08-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Cellvibrio japonicus alpha-L-arabinanase 43A has a novel five-blade beta-propeller fold. Nat. Struct. Biol., 9, 2002
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2OXC
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![BU of 2oxc by Molmil](/molmil-images/mine/2oxc) | Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Probable ATP-dependent RNA helicase DDX20 | Authors: | Karlberg, T, Ogg, D, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | Deposit date: | 2007-02-20 | Release date: | 2007-02-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Human DEAD-box RNA helicase DDX20 To be Published
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4ACX
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![BU of 4acx by Molmil](/molmil-images/mine/4acx) | Aminoimidazoles as BACE-1 Inhibitors. X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 23 | Descriptor: | (8R)-8-[4-(DIFLUOROMETHOXY)PHENYL]-3,3-DIFLUORO-8-[3-(3-METHOXYPROP-1-YN-1-YL)PHENYL]-2,3,4,8-TETRAHYDROIMIDAZO[1,5-A]PYRIMIDIN-6-AMINE, ACETATE ION, BETA-SECRETASE 1 | Authors: | Swahn, B, Holenz, J, Kihlstrom, J, Kolmodin, K, Lindstrom, J, Plobeck, N, Rotticci, D, Sehgelmeble, F, Sundstrom, M, von Berg, S, Falting, J, Georgievska, B, Gustavsson, S, Neelissen, J, Ek, M, Olsson, L.L, Berg, S. | Deposit date: | 2011-12-20 | Release date: | 2012-02-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy. Bioorg. Med. Chem. Lett., 22, 2012
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1GQJ
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![BU of 1gqj by Molmil](/molmil-images/mine/1gqj) | Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with xylobiose | Descriptor: | 1,2-ETHANEDIOL, ALPHA-D-GLUCURONIDASE, COBALT (II) ION, ... | Authors: | Nurizzo, D, Nagy, T, Gilbert, H.J, Davies, G.J. | Deposit date: | 2001-11-26 | Release date: | 2002-09-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Structural Basis for Catalysis and Specificity of the Pseudomonas Cellulosa Alpha-Glucuronidase, Glca67A Structure, 10, 2002
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4A21
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![BU of 4a21 by Molmil](/molmil-images/mine/4a21) | Structure of Mycobacterium tuberculosis fructose 1,6-bisphosphate aldolase bound to sulfate | Descriptor: | FRUCTOSE-BISPHOSPHATE ALDOLASE, SODIUM ION, SULFATE ION | Authors: | Coincon, M, De la Paz Santangelo, M, Gest, P.M, Guerin, M.E, Pham, H, Ryan, G, Puckett, S.E, Spencer, J.S, Gonzalez-Juarrero, M, Daher, R, Lenaerts, A.J, Schnappinger, D, Therisod, M, Ehrt, S, Jackson, M, Sygusch, J. | Deposit date: | 2011-09-21 | Release date: | 2011-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Glycolytic and Non-Glycolytic Functions of the Fructose-1,6-Bisphosphate Aldolase of Mycobacterium Tuberculosis, an Essential Enzyme Produced by Replicating and Non-Replicating Bacilli J.Biol.Chem., 286, 2011
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3KUC
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![BU of 3kuc by Molmil](/molmil-images/mine/3kuc) | Complex of Rap1A(E30D/K31E)GDP with RafRBD(A85K/N71R) | Descriptor: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Filchtinski, D, Sharabi, O, Rueppel, A, Vetter, I.R, Herrmann, C, Shifman, J.M. | Deposit date: | 2009-11-27 | Release date: | 2010-03-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf. J.Mol.Biol., 399, 2010
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2OZ8
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![BU of 2oz8 by Molmil](/molmil-images/mine/2oz8) | Crystal structure of putative mandelate racemase from Mesorhizobium loti | Descriptor: | Mll7089 protein, SULFATE ION | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Sridhar, V, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-02-25 | Release date: | 2007-03-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Crystal structure of putative mandelate racemase from Mesorhizobium loti To be Published
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