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Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:	Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J.
Deposit date:	2020-01-13
Release date:	2020-10-21
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.68 Å)
Cite:	Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020

6TWS

Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany with 2mM EDTA
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J.
Deposit date:	2020-01-13
Release date:	2020-10-21
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020

4MHI

Crystal structure of a H5N1 influenza virus hemagglutinin from A/goose/Guangdong/1/96
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:	Zhu, X, Wilson, I.A.
Deposit date:	2013-08-29
Release date:	2013-10-02
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.595 Å)
Cite:	A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin. J.Virol., 87, 2013

4MHH

Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/Viet Nam/1203/2004 (H5N1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H5M9 antibody, ...
Authors:	Zhu, X, Wilson, I.A.
Deposit date:	2013-08-29
Release date:	2013-10-02
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (3.564 Å)
Cite:	A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin. J.Virol., 87, 2013

6AOR

Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin apo form
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA2 chain, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-08-16
Release date:	2017-10-18
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017

6AOT

Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant in complex with 6'-SLNLN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-08-16
Release date:	2017-10-18
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13, 2017

6BKQ

Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin E190D mutant in complex with 6'-SLN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-11-09
Release date:	2018-02-28
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018

6BKO

Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin D190E mutant apo form
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-11-09
Release date:	2018-02-28
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018

6BKP

Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin apo form
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-11-09
Release date:	2018-02-28
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018

6BKN

Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin apo form
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-11-09
Release date:	2018-02-28
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018

6CA6

Crystal structure of PCT64_35S, a broadly neutralizing anti-HIV antibody.
Descriptor:	DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_35S heavy chain, ...
Authors:	Murrell, S, Wilson, I.A.
Deposit date:	2018-01-29
Release date:	2018-06-27
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.43 Å)
Cite:	Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design. Cell Rep, 23, 2018

6CA9

Crystal structure of Fab PCT64_LMCA (SAR), the least mutated common ancestor of the HIV-1 broadly neutralizing antibody lineage PCT64
Descriptor:	DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_LMCA Fab heavy chain, ...
Authors:	Omorodion, O, Wilson, I.A.
Deposit date:	2018-01-29
Release date:	2018-06-27
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.702 Å)
Cite:	Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design. Cell Rep, 23, 2018

6CA7

Crystal structure of PCT64_13C, a strain specific anti-HIV antibody
Descriptor:	PCT64_13C heavy chain, PCT64_13C light chain
Authors:	Murrell, S, Wilson, I.A.
Deposit date:	2018-01-29
Release date:	2018-06-27
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.643 Å)
Cite:	Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design. Cell Rep, 23, 2018

4NUG

Crystal structure of HIV-1 broadly neutralizing antibody PGT151
Descriptor:	HEXAETHYLENE GLYCOL, PGT151 heavy chain, PGT151 light chain
Authors:	Blattner, C, Wilson, I.A.
Deposit date:	2013-12-03
Release date:	2014-05-14
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.8617 Å)
Cite:	Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity, 40, 2014

6BKR

Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-11-09
Release date:	2018-02-28
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.76 Å)
Cite:	A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018

6BKM

Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin E190D mutant apo form
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-11-09
Release date:	2018-02-28
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018

6D2P

Crystal structure of IOMA-class CLK31 Fab from an HIV-1 naive donor in complex with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.6 A
Descriptor:	GLYCEROL, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, IOMAclass naive CLK31 Fab heavy chain, ...
Authors:	Sarkar, A, Wilson, I.A.
Deposit date:	2018-04-13
Release date:	2019-01-16
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen. Sci Transl Med, 10, 2018

4N62

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with a sulfated receptor analog
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:	Xu, R, Wilson, I.A.
Deposit date:	2013-10-11
Release date:	2013-12-18
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.5026 Å)
Cite:	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

6BKS

Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin D190E mutant in complex with 6'-SLN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-11-09
Release date:	2018-02-28
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018

4N63

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with an O-linked glycan receptor
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
Authors:	Xu, R, Wilson, I.A.
Deposit date:	2013-10-11
Release date:	2013-12-18
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.7522 Å)
Cite:	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4N5K

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTa
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:	Xu, R, Wilson, I.A.
Deposit date:	2013-10-10
Release date:	2013-12-18
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.7053 Å)
Cite:	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4N61

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTa, extended soaking
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
Authors:	Xu, R, Wilson, I.A.
Deposit date:	2013-10-11
Release date:	2013-12-18
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.6023 Å)
Cite:	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4N60

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTc
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:	Xu, R, Wilson, I.A.
Deposit date:	2013-10-11
Release date:	2013-12-18
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.9032 Å)
Cite:	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4NUJ

Crystal structure of HIV-1 broadly neutralizing antibody PGT152
Descriptor:	PGT152 heavy chain, PGT152 light chain
Authors:	Blattner, C, Wilson, I.A.
Deposit date:	2013-12-03
Release date:	2014-05-14
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.827 Å)
Cite:	Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity, 40, 2014

6BKT

Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:	Wu, N.C, Wilson, I.A.
Deposit date:	2017-11-09
Release date:	2018-02-28
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nat Commun, 9, 2018

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