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7T75
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BU of 7t75 by Molmil
HIV-1 Envelope ApexGT2 in complex with RM20A3 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV Envelope ApexGT2 gp120, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2021-12-14
Release date:2022-09-28
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity, 55, 2022
7T2P
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BU of 7t2p by Molmil
The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2021-12-06
Release date:2022-10-19
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.
Nat Commun, 13, 2022
7T4G
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BU of 7t4g by Molmil
The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Berndsen, Z.T, Ward, A.B.
Deposit date:2021-12-09
Release date:2022-10-19
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.
Nat Commun, 13, 2022
7T6X
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BU of 7t6x by Molmil
Cryo-EM structure of full-length hepatitis C virus E1E2 glycoprotein in complex with AR4A, AT12009, and IGH505 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AR4A Fab, ...
Authors:Torrents de la Pena, A, Ward, A.B, Eshun-Wilson, L, Lander, G.C.
Deposit date:2021-12-14
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (3.83 Å)
Cite:Structure of the hepatitis C virus E1E2 glycoprotein complex.
Science, 378, 2022
7TQU
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BU of 7tqu by Molmil
Coxsackievirus A21 capsid subdomain in complex with mouse polyclonal antibody pAbC-1
Descriptor: MYRISTIC ACID, VP1, VP2, ...
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2022-01-27
Release date:2023-01-04
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:High-resolution structural analysis of enterovirus-reactive polyclonal antibodies in complex with whole virions.
Pnas Nexus, 1, 2022
7TQS
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BU of 7tqs by Molmil
Coxsackievirus A21 capsid subdomain in complex with mouse polyclonal antibody pAbC-3
Descriptor: MYRISTIC ACID, VP1, VP2, ...
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2022-01-26
Release date:2023-01-04
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:High-resolution structural analysis of enterovirus-reactive polyclonal antibodies in complex with whole virions.
Pnas Nexus, 1, 2022
7TQT
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BU of 7tqt by Molmil
Coxsackievirus A21 capsid subdomain in complex with mouse polyclonal antibody pAbC-5
Descriptor: MYRISTIC ACID, VP1, VP2, ...
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2022-01-27
Release date:2023-01-04
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:High-resolution structural analysis of enterovirus-reactive polyclonal antibodies in complex with whole virions.
Pnas Nexus, 1, 2022
5CCK
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BU of 5cck by Molmil
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC315 Fab
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Antibody 3BC315 Fab heavy chain, Antibody 3BC315 Fab light chain
Authors:Lee, J.H, Ward, A.B, Wilson, I.A.
Deposit date:2015-07-02
Release date:2015-10-07
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
8D0Z
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BU of 8d0z by Molmil
S728-1157 IgG in complex with SARS-CoV-2-6P-Mut7 Spike protein (focused refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S728-1157 Fab heavy chain variable region, S728-1157 Fab light chain variable region, ...
Authors:Ozorowski, G, Torres, J.L, Ward, A.B.
Deposit date:2022-05-26
Release date:2023-03-22
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants.
J.Clin.Invest., 133, 2023
8DT8
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BU of 8dt8 by Molmil
LM18/Nb136 bispecific tetra-nanobody immunoglobulin in complex with SARS-CoV-2-6P-Mut7 S protein (focused refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, LM18 nanobody, Nb136 nanobody, ...
Authors:Ozorowski, G, Turner, H.L, Ward, A.B.
Deposit date:2022-07-25
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DYX
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BU of 8dyx by Molmil
Cryo-EM structure of 311 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 311 heavy chain, 311 light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-05
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DYY
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BU of 8dyy by Molmil
Cryo-EM structure of 334 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 334 Fab heavy chain, 334 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-05
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DZ5
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BU of 8dz5 by Molmil
Cryo-EM structure of 364 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 364 Fab heavy chain, 364 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-06
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DYW
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BU of 8dyw by Molmil
Cryo-EM structure of 239 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 239 Fab heavy chain, 239 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-05
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DZ3
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BU of 8dz3 by Molmil
Cryo-EM structure of 337 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 337 Fab heavy chain, 337 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-06
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DZ4
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BU of 8dz4 by Molmil
Cryo-EM structure of 356 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
Descriptor: 356 Fab heavy chain, 356 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-06
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8E6K
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BU of 8e6k by Molmil
2H08 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2H08 fragment antigen binding heavy chain, 2H08 fragment antigen binding light chain, ...
Authors:Turner, H.L, Ozorowski, G, Ward, A.B.
Deposit date:2022-08-22
Release date:2023-08-09
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
8DYT
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BU of 8dyt by Molmil
Cryo-EM structure of 227 Fab in complex with (NPNA)8 peptide
Descriptor: 227 Fab heavy chain, 227 Fab light chain, Circumsporozoite protein
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-08-05
Release date:2023-08-02
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8E6J
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BU of 8e6j by Molmil
3H03 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
Descriptor: 3H03 fragment antigen binding heavy chain, 3H03 fragment antigen binding light chain, Neuraminidase
Authors:Turner, H.L, Ozorowski, G, Ward, A.B.
Deposit date:2022-08-22
Release date:2023-08-09
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
8EH5
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BU of 8eh5 by Molmil
Cryo-EM structure of L9 Fab in complex with rsCSP
Descriptor: Circumsporozoite protein, L9 Heavy chain, L9 Light chain
Authors:Martin, G.M, Ward, A.B.
Deposit date:2022-09-13
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9.
Nat Commun, 14, 2023
8EQN
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BU of 8eqn by Molmil
BG505 UFO-E2p-L4P nanoparticle reconstructed by focused refinement with a mask around the nanoparticle core
Descriptor: BG505 UFO-E2p-L4P
Authors:Antanasijevic, A, Zhang, Y.N, Zhu, J, Ward, A.B.
Deposit date:2022-10-08
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimmers as HIV-1 vaccine candidates.
Nat Commun, 14, 2023
8EJE
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BU of 8eje by Molmil
Structure of lineage II Lassa virus glycoprotein complex (strain NIG08-A41)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein GP1, ...
Authors:Perrett, H.R, Ward, A.B.
Deposit date:2022-09-16
Release date:2023-06-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJH
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BU of 8ejh by Molmil
Lassa virus glycoprotein complex (Josiah) bound to 12.1F Fab
Descriptor: 12.1F Fab heavy chain, 12.1F Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Perrett, H.R, Ward, A.B.
Deposit date:2022-09-16
Release date:2023-06-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJF
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BU of 8ejf by Molmil
Structure of lineage V Lassa virus glycoprotein complex (strain Soromba-R)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Perrett, H.R, Ward, A.B.
Deposit date:2022-09-16
Release date:2023-06-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
8EJG
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BU of 8ejg by Molmil
Structure of lineage VII Lassa virus glycoprotein complex (strain Togo/2016/7082)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein GP1, ...
Authors:Perrett, H.R, Ward, A.B.
Deposit date:2022-09-16
Release date:2023-06-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023

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数据于2024-06-12公开中

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