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7ZYU
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BU of 7zyu by Molmil
HDAC6 ZnF domain inhibitor - DARPin (Designed Ankyrin repeat protein) F10
Descriptor: 1,2-ETHANEDIOL, Designed Ankyrin repeat protein F10, Histone deacetylase 6, ...
Authors:Wang, L, Kempf, G.
Deposit date:2022-05-25
Release date:2022-06-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways.
Cell Rep, 39, 2022
6MIZ
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BU of 6miz by Molmil
Human TRPM2 ion channel in an ADPR-bound state
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Wang, L, Fu, T.M, Xia, S, Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6MJ2
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BU of 6mj2 by Molmil
Human TRPM2 ion channel in a calcium- and ADPR-bound state
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 2
Authors:Wang, L, Fu, T.M, Xia, S, Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (6.36 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
6MIX
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BU of 6mix by Molmil
Human TRPM2 ion channel in apo state
Descriptor: Transient receptor potential cation channel subfamily M member 2
Authors:Wang, L, Fu, T.M, Xia, S, Wu, H.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and gating mechanism of human TRPM2.
Science, 362, 2018
7VHM
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BU of 7vhm by Molmil
Double deletion S-2P trimer(3 down)
Descriptor: Spike glycoprotein
Authors:Wang, L, Wang, X, Wang, X.
Deposit date:2021-09-22
Release date:2022-10-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Double deletion S-2P trimer(3 down)
To Be Published
7DV5
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BU of 7dv5 by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
Descriptor: Bile salt export pump, TAUROCHOLIC ACID
Authors:Wang, L, How, W.T, Chen, Y.
Deposit date:2021-01-12
Release date:2022-01-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
7E1A
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BU of 7e1a by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
Descriptor: Bile salt export pump, TAUROCHOLIC ACID
Authors:Wang, L, How, W.T, Chen, Y.
Deposit date:2021-02-01
Release date:2022-02-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
7KH0
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BU of 7kh0 by Molmil
Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex
Descriptor: Arg-vasopressin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wang, L, Xu, J, Gao, S, Sun, D, Liu, H, Liu, Z, Du, Y, Zhang, C.
Deposit date:2020-10-19
Release date:2021-05-26
Last modified:2023-03-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of the AVP-vasopressin receptor 2-G s signaling complex.
Cell Res., 31, 2021
7LHV
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BU of 7lhv by Molmil
Structure of Arabidopsis thaliana sulfate transporter AtSULTR4;1
Descriptor: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SULFATE ION, ...
Authors:Wang, L, Chen, K, Zhou, M.
Deposit date:2021-01-26
Release date:2021-08-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structure and function of an Arabidopsis thaliana sulfate transporter.
Nat Commun, 12, 2021
2LKU
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BU of 2lku by Molmil
Solution structure of reduced poplar apo GrxS14
Descriptor: GrxS14
Authors:Wang, L, Xia, B.
Deposit date:2011-10-21
Release date:2012-10-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of reduced poplar apo GrxS14
To be Published
6K5E
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BU of 6k5e by Molmil
Crystal structure of BioH from Klebsiella pneumonia
Descriptor: Pimeloyl-[acyl-carrier protein] methyl ester esterase
Authors:Wang, L, Chen, Y.
Deposit date:2019-05-28
Release date:2019-07-17
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (2.257 Å)
Cite:Structural insight into the carboxylesterase BioH from Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 520, 2019
6KG7
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BU of 6kg7 by Molmil
Cryo-EM Structure of the Mammalian Tactile Channel Piezo2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Piezo-type mechanosensitive ion channel component 2
Authors:Wang, L, Zhou, H, Zhang, M, Liu, W, Deng, T, Zhao, Q, Li, Y, Lei, J, Li, X, Xiao, B.
Deposit date:2019-07-11
Release date:2019-09-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure and mechanogating of the mammalian tactile channel PIEZO2.
Nature, 573, 2019
6L3E
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BU of 6l3e by Molmil
Crystal structure of Salmonella enterica sugar-binding protein MalE
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ...
Authors:Wang, L, Chen, Y, Liu, W, Lan, J, Shang, F, Xu, Y.
Deposit date:2019-10-10
Release date:2019-10-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of Salmonella enterica sugar-binding protein MalE
To Be Published
2LKT
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BU of 2lkt by Molmil
Solution structure of N-terminal domain of human TIG3 in 2 M UREA
Descriptor: Retinoic acid receptor responder protein 3
Authors:Wang, L, Yu, W, Xia, B.
Deposit date:2011-10-21
Release date:2012-10-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:(1)H, (13)C, and (15)N resonance assignments of the N-terminal domain of human TIG3
Biomol.Nmr Assign., 6, 2012
7UPR
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BU of 7upr by Molmil
Human mitochondrial AAA protein ATAD1 (with a catalytic dead mutation) in complex with a peptide substrate (closed conformation)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Outer mitochondrial transmembrane helix translocase, ...
Authors:Wang, L, Toutkoushian, H, Belyy, V, Kokontis, C, Walter, P.
Deposit date:2022-04-16
Release date:2022-06-15
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Conserved structural elements specialize ATAD1 as a membrane protein extraction machine.
Elife, 11, 2022
7UPT
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BU of 7upt by Molmil
Human mitochondrial AAA protein ATAD1 (with a catalytic dead mutation) in complex with a peptide substrate (open conformation)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Wang, L, Toutkoushian, H, Belyy, V, Kokontis, C, Walter, P.
Deposit date:2022-04-16
Release date:2022-06-15
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conserved structural elements specialize ATAD1 as a membrane protein extraction machine.
Elife, 11, 2022
7FFT
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BU of 7fft by Molmil
The crystal structure of a domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica
Descriptor: Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Wang, L, Bu, T, Bai, X.
Deposit date:2021-07-23
Release date:2021-09-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica.
Acta Crystallogr D Struct Biol, 78, 2022
7FFW
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BU of 7ffw by Molmil
The crystal structure of a domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, METHOXYETHANE, ...
Authors:Wang, L, Bu, T, Bai, X.
Deposit date:2021-07-23
Release date:2021-09-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica.
Acta Crystallogr D Struct Biol, 78, 2022
2OA4
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BU of 2oa4 by Molmil
Solution NMR Structure: Northeast Structural Genomics Consortium Target SiR5
Descriptor: SiR5
Authors:Wang, L, Rossi, P, Chen, C.X, Nwosu, C, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Burkhard, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-12-14
Release date:2007-03-06
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Northeast Structural Genomics Consortium Target SiR5
To be Published
2OT2
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BU of 2ot2 by Molmil
Solution Structure of HypC
Descriptor: Hydrogenase isoenzymes formation protein hypC
Authors:Wang, L, Jin, C.
Deposit date:2007-02-07
Release date:2007-09-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of Escherichia coli HypC
Biochem.Biophys.Res.Commun., 361, 2007
7EPU
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BU of 7epu by Molmil
Crystal structure of HsALC1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chromodomain-helicase-DNA-binding protein 1-like, MAGNESIUM ION, ...
Authors:Wang, L, Chen, K.J.
Deposit date:2021-04-27
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.
Nat Commun, 12, 2021
7F8E
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BU of 7f8e by Molmil
Crystal structure of YggS from Fusobacterium nucleatum
Descriptor: Pyridoxal phosphate homeostasis protein, SULFATE ION
Authors:Wang, L, Chen, Y, Bu, T, Bai, X.
Deposit date:2021-07-02
Release date:2022-01-12
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structure of YggS from Fusobacterium nucleatum
To Be Published
2PVX
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BU of 2pvx by Molmil
NMR and X-ray Analysis of Structural Additivity in Metal Binding Site-Swapped Hybrids of Rubredoxin
Descriptor: Rubredoxin, ZINC ION
Authors:Wang, L, LeMaster, D.M, Hernandez, G, Li, H.
Deposit date:2007-05-10
Release date:2007-12-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin
Bmc Struct.Biol., 7, 2007
7XJA
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BU of 7xja by Molmil
TMD masked refine map of human ClC-2
Descriptor: Chloride channel protein 2
Authors:Wang, L.
Deposit date:2022-04-15
Release date:2023-05-17
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42
Nat Commun, 14, 2023
7XF5
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BU of 7xf5 by Molmil
Full length human CLC-2 channel in apo state
Descriptor: Chloride channel protein 2
Authors:Wang, L.
Deposit date:2022-04-01
Release date:2023-05-03
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42
Nat Commun, 14, 2023

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数据于2024-10-02公开中

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