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3HF9
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BU of 3hf9 by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant modified by inhibitor GL1
Descriptor: Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D, Li, H.
Deposit date:2009-05-11
Release date:2009-09-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.878 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
3H6I
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BU of 3h6i by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome Modified by inhibitor GL1
Descriptor: DIMETHYLFORMAMIDE, Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D, Li, H, Lin, G.
Deposit date:2009-04-23
Release date:2009-09-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
1DMK
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BU of 1dmk by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 4-AMINO-6-PHENYL-TETRAHYDROPTERIDINE
Descriptor: 2,4-DIAMINO-6-PHENYL-5,6,7,8,-TETRAHYDROPTERIDINE, ACETATE ION, CACODYLATE ION, ...
Authors:Kotsonis, P, Frohlich, L.G, Raman, C.S, Li, H, Berg, M, Gerwig, R, Groehn, V, Kang, Y, Al-Masoudi, N, Taghavi-Moghadam, S, Mohr, D, Munch, U, Schnabel, J, Martasek, P, Masters, B.S, Strobel, H, Poulos, T, Matter, H, Pfleiderer, W, Schmidt, H.H.
Deposit date:1999-12-14
Release date:2000-12-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001
3H6F
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BU of 3h6f by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome Modified by inhibitor HT1171
Descriptor: DIMETHYLFORMAMIDE, Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D, Li, H, Lin, G.
Deposit date:2009-04-23
Release date:2009-09-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
6VSI
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BU of 6vsi by Molmil
Crystal structure of FKBP12 of Candida auris
Descriptor: Peptidylprolyl isomerase, SULFATE ION
Authors:Li, Z, Li, H, Hernandez, G, LeMaster, D.
Deposit date:2020-02-11
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structure and transient dimerization for the FKBP12 protein from the pathogenic fungus Candida auris.
Biochem.Biophys.Res.Commun., 525, 2020
1NI6
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BU of 1ni6 by Molmil
Comparisions of the Heme-Free and-Bound Crystal Structures of Human Heme Oxygenase-1
Descriptor: CHLORIDE ION, Heme oxygenase 1, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
Authors:Lad, L, Schuller, D.J, Friedman, J, Li, H, Shimizu, H, Ortiz de Montellano, P.R, Poulos, T.L.
Deposit date:2002-12-21
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1
J.Biol.Chem., 278, 2003
1DMJ
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BU of 1dmj by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 5,6-CYCLIC-TETRAHYDROPTERIDINE
Descriptor: 7-AMINO-3,3A,4,5-TETRAHYDRO-8H-2-OXA-5,6,8,9B-TETRAAZA-CYCLOPENTA[A]NAPHTHALENE-1,9-DIONE, ACETATE ION, CACODYLATE ION, ...
Authors:Kotsonis, P, Frohlich, L.G, Raman, C.S, Li, H, Berg, M, Gerwig, R, Groehn, V, Kang, Y, Al-Masoudi, N, Taghavi-Moghadam, S, Mohr, D, Munch, U, Schnabel, J, Martasek, P, Masters, B.S, Strobel, H, Poulos, T, Matter, H, Pfleiderer, W, Schmidt, H.H.
Deposit date:1999-12-14
Release date:2000-12-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001
4RLI
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BU of 4rli by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048
Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhu, L, Ren, X, Zhu, J, Li, H.
Deposit date:2014-10-17
Release date:2015-11-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048
TO BE PUBLISHED
4RV5
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BU of 4rv5 by Molmil
The crystal structure of a solute-binding protein from Anabaena variabilis ATCC 29413 in complex with pyruvic acid
Descriptor: Amino acid/amide ABC transporter substrate-binding protein, HAAT family, FORMIC ACID, ...
Authors:Tan, K, Li, H, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-11-24
Release date:2014-12-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:The crystal structure of a solute-binding protein from Anabaena variabilis ATCC 29413 in complex with pyruvic acid
To be Published
4RK8
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BU of 4rk8 by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A356
Descriptor: 5-fluoro-2-{[(5Z)-5-(naphthalen-1-ylmethylidene)-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]amino}benzoic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Zhu, L, Ren, X, Zhu, J, Li, H.
Deposit date:2014-10-12
Release date:2015-11-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A356
TO BE PUBLISHED
4TKT
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BU of 4tkt by Molmil
Streptomyces platensis isomigrastatin ketosynthase domain MgsF KS6
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AT-less polyketide synthase, CHLORIDE ION, ...
Authors:Chang, C, Li, H, Endres, M, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-05-27
Release date:2014-06-11
Last modified:2023-03-22
Method:X-RAY DIFFRACTION (2.4289 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4UH7
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BU of 4uh7 by Molmil
Structure of bovine endothelial nitric oxide synthase heme domain in complex with N1-(3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)phenyl)-N1, N2-dimethylethane-1,2-diamine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, GLYCEROL, ...
Authors:Chreifi, G, Li, H, Poulos, T.L.
Deposit date:2015-03-23
Release date:2015-07-15
Last modified:2015-08-05
Method:X-RAY DIFFRACTION (2.235 Å)
Cite:2-Aminopyridines with a Truncated Side Chain to Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity.
J.Med.Chem., 58, 2015
6WPG
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BU of 6wpg by Molmil
Structural Basis of Salicylic Acid Perception by Arabidopsis NPR Proteins
Descriptor: 2-HYDROXYBENZOIC ACID, Regulatory protein NPR4
Authors:Wang, W, Withers, J, Li, H, Zwack, P.J, Rusnac, D.V, Shi, H, Liu, L, Yan, S, Hinds, T.R, Guttman, M, Dong, X, Zheng, N.
Deposit date:2020-04-27
Release date:2020-08-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.283 Å)
Cite:Structural basis of salicylic acid perception by Arabidopsis NPR proteins.
Nature, 586, 2020
1N3U
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BU of 1n3u by Molmil
Crystal structure of human heme oxygenase 1 (HO-1) in complex with its substrate heme, crystal form B
Descriptor: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, heme oxygenase 1
Authors:Lad, L, Schuller, D.J, Friedman, J.P, Li, H, Ortiz de Montellano, P.R, Poulos, T.L.
Deposit date:2002-10-29
Release date:2002-11-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1
J.Biol.Chem., 278, 2003
3MKA
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BU of 3mka by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome with propetide and an T1A mutation at beta-subunit
Descriptor: Proteasome subunit alpha, Proteasome subunit beta
Authors:Li, D, Li, H.
Deposit date:2010-04-14
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 29, 2010
3MI0
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BU of 3mi0 by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome at 2.2 A
Descriptor: (2R,3S,4R)-2-[(S)-(1S)-cyclohex-2-en-1-yl(hydroxy)methyl]-4-ethyl-3-hydroxy-3-methyl-5-oxopyrrolidine-2-carbaldehyde, DIMETHYLFORMAMIDE, Proteasome subunit alpha, ...
Authors:Li, D, Li, H.
Deposit date:2010-04-09
Release date:2010-06-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 2010
1P3T
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BU of 1p3t by Molmil
Crystal Structures of the NO-and CO-Bound Heme Oxygenase From Neisseria Meningitidis: Implications for Oxygen Activation
Descriptor: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Friedman, J, Lad, L, Deshmukh, R, Li, H, Wilks, A, Poulos, T.L.
Deposit date:2003-04-18
Release date:2003-12-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the NO- and CO-bound heme oxygenase from Neisseriae meningitidis. Implications for O2 activation
J.Biol.Chem., 278, 2003
1P3V
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BU of 1p3v by Molmil
Crystal Structures of the NO-and CO-Bound Heme Oxygenase From Neisseria Meningitidis: Implications for Oxygen Activation
Descriptor: CARBON MONOXIDE, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Friedman, J, Lad, L, Deshmukh, R, Li, H, Wilks, A, Poulos, T.L.
Deposit date:2003-04-18
Release date:2003-12-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structures of the NO- and CO-bound heme oxygenase from Neisseriae meningitidis. Implications for O2 activation
J.Biol.Chem., 278, 2003
7SUK
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BU of 7suk by Molmil
Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted Yeast Cells
Descriptor: 18S pre-rRNA, 40S ribosomal protein S11-A, 40S ribosomal protein S13, ...
Authors:Rai, J, Zhao, Y, Li, H.
Deposit date:2021-11-17
Release date:2022-07-06
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome.
Commun Biol, 5, 2022
1P3U
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BU of 1p3u by Molmil
Crystal Structures of the NO-and CO-Bound Heme Oxygenase From Neisseria Meningitidis: Implications for Oxygen Activation
Descriptor: Heme oxygenase 1, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Friedman, J, Lad, L, Deshmukh, R, Li, H, Wilks, A, Poulos, T.L.
Deposit date:2003-04-18
Release date:2003-12-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of the NO- and CO-bound heme oxygenase from Neisseriae meningitidis. Implications for O2 activation
J.Biol.Chem., 278, 2003
3MFE
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BU of 3mfe by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant with H0 movement
Descriptor: Proteasome subunit alpha, Proteasome subunit beta
Authors:Li, D, Li, H.
Deposit date:2010-04-02
Release date:2010-06-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 2010
6W6G
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BU of 6w6g by Molmil
The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation I in the presence of DnaK chaperone and a model substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Yin, Y, Li, H.
Deposit date:2020-03-16
Release date:2021-03-17
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Cell Rep, 35, 2021
6W6H
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BU of 6w6h by Molmil
The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation II in the presence of DnaK chaperone and a model substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Yin, Y, Li, H.
Deposit date:2020-03-16
Release date:2021-05-26
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Cell Rep, 35, 2021
6W6I
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BU of 6w6i by Molmil
The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation T in the presence of DnaK chaperone and a model substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Yin, Y, Li, H.
Deposit date:2020-03-17
Release date:2021-05-26
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Cell Rep, 35, 2021
6W6E
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BU of 6w6e by Molmil
The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with a locally refined ClpB middle domain and a DnaK nucleotide binding domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, Chaperone protein DnaK, ...
Authors:Yin, Y, Li, H.
Deposit date:2020-03-16
Release date:2021-05-26
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Cell Rep, 35, 2021

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数据于2024-06-19公开中

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