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7WSE
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BU of 7wse by Molmil
Cryo-EM structure of SARS-CoV-2 spike receptor-binding domain complexed with its receptor minke whale ACE2
Descriptor: Angiotensin-converting enzyme, Spike protein S1, ZINC ION
Authors:Li, S, Han, P.
Deposit date:2022-01-29
Release date:2022-10-19
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals.
Natl Sci Rev, 9, 2022
7WSH
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BU of 7wsh by Molmil
Cryo-EM structure of SARS-CoV-2 spike receptor-binding domain in complex with sea lion ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ...
Authors:Li, S, Han, P, Qi, J.
Deposit date:2022-01-29
Release date:2022-11-09
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals.
Natl Sci Rev, 9, 2022
7WSG
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BU of 7wsg by Molmil
Cryo-EM structure of SARS-CoV spike receptor-binding domain in complex with sea lion ACE2
Descriptor: Angiotensin-converting enzyme, Spike protein S1, ZINC ION
Authors:Li, S, Han, P, Qi, J.
Deposit date:2022-01-29
Release date:2022-11-09
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals.
Natl Sci Rev, 9, 2022
6PSJ
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BU of 6psj by Molmil
Bazedoxifene in Complex with Y537S Estrogen Receptor Alpha Ligand Binding Domain
Descriptor: Bazedoxifene, Estrogen receptor
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2019-07-12
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022
7WBQ
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BU of 7wbq by Molmil
Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant spike glycoprotein in complex with its receptor human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Qi, J, Han, P.
Deposit date:2021-12-17
Release date:2022-01-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2.
Cell, 185, 2022
7WBP
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BU of 7wbp by Molmil
Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron variant spike glycoprotein in complex with its receptor human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Qi, J, Han, P.
Deposit date:2021-12-17
Release date:2022-01-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2.
Cell, 185, 2022
7WRH
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BU of 7wrh by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Han, P, Xie, Y, Qi, J.
Deposit date:2022-01-26
Release date:2023-02-01
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s.
Cell Discov, 8, 2022
7WRI
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BU of 7wri by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike receptor-binding domain in complex with mouse ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Han, P, Xie, Y, Qi, J.
Deposit date:2022-01-26
Release date:2022-06-08
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s.
Cell Discov, 8, 2022
7WSK
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BU of 7wsk by Molmil
Crystal structure of SARS-CoV-2 Omicron spike receptor-binding domain in complex with civet ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:Huang, B, Han, P, Qi, J.
Deposit date:2022-01-29
Release date:2022-06-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s.
Cell Discov, 8, 2022
6LB7
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BU of 6lb7 by Molmil
Crystal structure of the Ca2+-free and Ca2+-bound MICU1-MICU2 complex
Descriptor: CALCIUM ION, Calcium uptake protein 1, mitochondrial, ...
Authors:Wu, W, Shen, Q, Zheng, J, Jia, Z.
Deposit date:2019-11-13
Release date:2020-07-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter.
Embo J., 39, 2020
5ZBQ
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BU of 5zbq by Molmil
The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299
Descriptor: Neuropeptide Y receptor type 1,T4 Lysozyme, N~2~-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-N~5~-(N'-{[2-(propanoylamino)ethyl]carbamoyl}carbamimidoyl)-D-ornithinamide
Authors:Yang, Z, Han, S, Zhao, Q, Wu, B.
Deposit date:2018-02-12
Release date:2018-04-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of ligand binding modes at the neuropeptide Y Y1receptor
Nature, 556, 2018
7WBL
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BU of 7wbl by Molmil
Cryo-EM structure of human ACE2 complexed with SARS-CoV-2 Omicron RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:Liu, S, Gao, F.G.
Deposit date:2021-12-17
Release date:2022-01-19
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2.
Cell, 185, 2022
5ZBH
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BU of 5zbh by Molmil
The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885
Descriptor: Neuropeptide Y receptor type 1,T4 Lysozyme,Neuropeptide Y receptor type 1, dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Authors:Yang, Z, Han, S, Zhao, Q, Wu, B.
Deposit date:2018-02-11
Release date:2018-04-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of ligand binding modes at the neuropeptide Y Y1receptor
Nature, 556, 2018
6TUR
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BU of 6tur by Molmil
human XPG, Apo1 form
Descriptor: DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells
Authors:Ruiz, F.M, Fernandez-Tornero, C.
Deposit date:2020-01-08
Release date:2020-09-16
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
6TUX
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BU of 6tux by Molmil
human XPG-DNA, Complex 2
Descriptor: DNA (5'-D(P*AP*AP*CP*TP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*GP*AP*GP*TP*T)-3'), DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells
Authors:Ruiz, F.M, Fernandez-Tornero, C.
Deposit date:2020-01-08
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
6TUW
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BU of 6tuw by Molmil
human XPG-DNA, Complex 1
Descriptor: DNA (5'-D(P*GP*AP*AP*CP*TP*CP*TP*G)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*AP*GP*TP*TP*C)-3'), DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells
Authors:Ruiz, F.M, Fernandez-Tornero, C.
Deposit date:2020-01-08
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
6TUS
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BU of 6tus by Molmil
human XPG, Apo2 form
Descriptor: DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells, GLYCEROL, SULFATE ION
Authors:Ruiz, F.M, Fernandez-Tornero, C.
Deposit date:2020-01-08
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
7L49
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BU of 7l49 by Molmil
Cryo-EM structure of CRISPR-Cas12f Ternary Complex
Descriptor: Cas12f1, NTS, Substrate, ...
Authors:Chang, L, Li, Z.
Deposit date:2020-12-18
Release date:2021-06-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR-Cas12f nuclease.
Nucleic Acids Res., 49, 2021
7L48
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BU of 7l48 by Molmil
Cryo-EM structure of a CRISPR-Cas12f Binary Complex
Descriptor: Cas12f, ZINC ION, sgRNA
Authors:Chang, L, Li, Z.
Deposit date:2020-12-18
Release date:2021-06-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR-Cas12f nuclease.
Nucleic Acids Res., 49, 2021
5HSI
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BU of 5hsi by Molmil
Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution
Descriptor: MAGNESIUM ION, Putative decarboxylase
Authors:Ni, Y, Zhou, J, Zhu, H, Zhang, K.
Deposit date:2016-01-25
Release date:2016-09-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.732 Å)
Cite:Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
7UJ7
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BU of 7uj7 by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with RU39411
Descriptor: 11alpha-{4-[2-(dimethylamino)ethoxy]phenyl}estra-1(10),2,4-triene-3,17beta-diol, Estrogen receptor
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2022-03-30
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022
7UJC
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BU of 7ujc by Molmil
Raloxifene in Complex with Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutation
Descriptor: Estrogen receptor, RALOXIFENE
Authors:Hosfield, D.J, Greene, G.L, Fanning, S.W.
Deposit date:2022-03-30
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022
7UJ8
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BU of 7uj8 by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 4-Hydroxytamoxifen
Descriptor: 4-HYDROXYTAMOXIFEN, Estrogen receptor
Authors:Hosfield, D.J, Greene, G.L, Fanning, S.W.
Deposit date:2022-03-30
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.385 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022
7UJF
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BU of 7ujf by Molmil
Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Methylated Lasofoxifene Derivative with Selective Estrogen Receptor Degrader Properties
Descriptor: (5R,6S)-5-(4-{2-[(3S)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-6-phenyl-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor
Authors:Hosfield, D.J, Greene, G.L, Fanning, S.W.
Deposit date:2022-03-30
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022
7UJW
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BU of 7ujw by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with a Methylated Lasofoxifene Derivative that Possesses Selective Estrogen Receptor Degrader Activities
Descriptor: (5R,6S)-5-(4-{2-[(3S)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-6-phenyl-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor
Authors:Hosfield, D.J, Greene, G.L, Fanning, S.W.
Deposit date:2022-03-31
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Elife, 11, 2022

238582

数据于2025-07-09公开中

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