1J04
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![BU of 1j04 by Molmil](/molmil-images/mine/1j04) | Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro | Descriptor: | (AMINOOXY)ACETIC ACID, GLYCEROL, alanine--glyoxylate aminotransferase | Authors: | Zhang, X, Djordjevic, S, Bartlam, M, Ye, S, Rao, Z, Danpure, C.J. | Deposit date: | 2002-10-30 | Release date: | 2003-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting. Acta Crystallogr.,Sect.F, 66, 2010
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6CU7
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![BU of 6cu7 by Molmil](/molmil-images/mine/6cu7) | Alpha Synuclein fibril formed by full length protein - Rod Polymorph | Descriptor: | Alpha-synuclein | Authors: | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | Deposit date: | 2018-03-23 | Release date: | 2018-09-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9, 2018
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6CU8
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![BU of 6cu8 by Molmil](/molmil-images/mine/6cu8) | Alpha Synuclein fibril formed by full length protein - Twister Polymorph | Descriptor: | Alpha-synuclein | Authors: | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | Deposit date: | 2018-03-23 | Release date: | 2018-09-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9, 2018
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6KKU
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![BU of 6kku by Molmil](/molmil-images/mine/6kku) | human KCC1 structure determined in NaCl and GDN | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | Deposit date: | 2019-07-27 | Release date: | 2019-10-23 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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6KKT
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![BU of 6kkt by Molmil](/molmil-images/mine/6kkt) | human KCC1 structure determined in KCl and lipid nanodisc | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | Deposit date: | 2019-07-27 | Release date: | 2019-10-23 | Last modified: | 2020-08-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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6KKR
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![BU of 6kkr by Molmil](/molmil-images/mine/6kkr) | human KCC1 structure determined in KCl and detergent GDN | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | Deposit date: | 2019-07-27 | Release date: | 2019-10-23 | Last modified: | 2020-08-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science, 366, 2019
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6M68
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![BU of 6m68 by Molmil](/molmil-images/mine/6m68) | The Cryo-EM Structure of Human Pannexin 1 in the Presence of CBX | Descriptor: | Pannexin-1 | Authors: | Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. | Deposit date: | 2020-03-13 | Release date: | 2020-04-15 | Last modified: | 2020-05-13 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Cryo-EM structures of human pannexin 1 channel. Cell Res., 30, 2020
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6M66
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![BU of 6m66 by Molmil](/molmil-images/mine/6m66) | The Cryo-EM Structure of Human Pannexin 1 | Descriptor: | Pannexin-1 | Authors: | Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S. | Deposit date: | 2020-03-13 | Release date: | 2020-04-15 | Last modified: | 2020-05-13 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structures of human pannexin 1 channel. Cell Res., 30, 2020
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3R65
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![BU of 3r65 by Molmil](/molmil-images/mine/3r65) | MthK channel pore E92Q mutant | Descriptor: | Calcium-gated potassium channel mthK, POTASSIUM ION | Authors: | Shi, N, Zeng, W, Ye, S, Li, Y, Jiang, Y. | Deposit date: | 2011-03-21 | Release date: | 2012-02-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crucial points within the pore as determinants of K+ channel conductance and gating J.Mol.Biol., 411, 2011
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5Y8E
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![BU of 5y8e by Molmil](/molmil-images/mine/5y8e) | |
5YHU
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![BU of 5yhu by Molmil](/molmil-images/mine/5yhu) | |
5Y8F
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![BU of 5y8f by Molmil](/molmil-images/mine/5y8f) | |
5YYM
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![BU of 5yym by Molmil](/molmil-images/mine/5yym) | Crystal structures of E.coli arginyl-trna synthetase (argrs) in complex with substrate Arg | Descriptor: | ARGININE, Arginine--tRNA ligase | Authors: | Zhou, M, Ye, S, Stephen, P, Zhang, R.G, Wang, E.D, Giege, R, Lin, S.X. | Deposit date: | 2017-12-10 | Release date: | 2018-12-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures Of E.Coli Arginyl-Trna Synthetase (Argrs) In Complex With Substrates To Be Published
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5YYN
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![BU of 5yyn by Molmil](/molmil-images/mine/5yyn) | Crystal structures of E.coli arginyl-trna synthetase (argrs) in complex with substrate TRNA(Arg) | Descriptor: | Arginine--tRNA ligase, TRNA | Authors: | Zhou, M, Ye, S, Stephen, P, Zhang, R.G, Wang, E.D, Giege, R, Lin, S.X. | Deposit date: | 2017-12-10 | Release date: | 2018-12-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structures Of E.Coli Arginyl-Trna Synthetase (Argrs) In Complex With Substrates To Be Published
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5ZHU
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![BU of 5zhu by Molmil](/molmil-images/mine/5zhu) | |
5ZUE
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![BU of 5zue by Molmil](/molmil-images/mine/5zue) | GTP-bound, double-stranded, curved FtsZ protofilament structure | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE | Authors: | Guan, F, Yu, J, Yu, J, Liu, Y, Li, Y, Feng, X.H, Huang, K.C, Chang, Z, Ye, S. | Deposit date: | 2018-05-07 | Release date: | 2018-07-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Lateral interactions between protofilaments of the bacterial tubulin homolog FtsZ are essential for cell division Elife, 7, 2018
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4KWE
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![BU of 4kwe by Molmil](/molmil-images/mine/4kwe) | GDP-bound, double-stranded, curved FtsZ protofilament structure | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | Authors: | Li, Y, Hsin, J, Zhao, L, Cheng, Y, Shang, W, Huang, K.C, Wang, H.W, Ye, S. | Deposit date: | 2013-05-23 | Release date: | 2013-07-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | FtsZ protofilaments use a hinge-opening mechanism for constrictive force generation Science, 341, 2013
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6JGY
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![BU of 6jgy by Molmil](/molmil-images/mine/6jgy) | Crystal structure of LASV-GP2 in a post fusion conformation | Descriptor: | Pre-glycoprotein polyprotein GP complex | Authors: | Zhu, Y, Zhang, X, Chen, B, Ye, S, Zhang, R. | Deposit date: | 2019-02-15 | Release date: | 2019-09-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.389 Å) | Cite: | Crystal Structure of Refolding Fusion Core of Lassa Virus GP2 and Design of Lassa Virus Fusion Inhibitors. Front Microbiol, 10, 2019
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7YVC
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![BU of 7yvc by Molmil](/molmil-images/mine/7yvc) | Aplysia californica FaNaC in apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S. | Deposit date: | 2022-08-19 | Release date: | 2023-08-09 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily. Nat.Chem.Biol., 19, 2023
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7YVB
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![BU of 7yvb by Molmil](/molmil-images/mine/7yvb) | Aplysia californica FaNaC in ligand bound state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FMRFamide-gated Na+ channel, ... | Authors: | Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S. | Deposit date: | 2022-08-19 | Release date: | 2023-08-09 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily. Nat.Chem.Biol., 19, 2023
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5H0N
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![BU of 5h0n by Molmil](/molmil-images/mine/5h0n) | |
4RF9
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![BU of 4rf9 by Molmil](/molmil-images/mine/4rf9) | Crystal structure of double-domain arginine kinase from Anthopleura japonicas in complex with L-arginine and ATPgS | Descriptor: | ACETATE ION, ARGININE, Arginine kinase, ... | Authors: | Wang, Z, Qiao, Z, Ye, S, Zhang, R. | Deposit date: | 2014-09-25 | Release date: | 2015-04-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of a double-domain phosphagen kinase reveals an asymmetric arrangement of the tandem domains. Acta Crystallogr.,Sect.D, 71, 2015
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4QE7
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![BU of 4qe7 by Molmil](/molmil-images/mine/4qe7) | Open MthK pore structure soaked in 10 mM Ba2+/100 mM Na+ | Descriptor: | BARIUM ION, Calcium-gated potassium channel MthK | Authors: | Guo, R, Zeng, W, Cui, H, Chen, L, Ye, S. | Deposit date: | 2014-05-15 | Release date: | 2014-07-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Ionic interactions of Ba2+ blockades in the MthK K+ channel J.Gen.Physiol., 144, 2014
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4QE9
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![BU of 4qe9 by Molmil](/molmil-images/mine/4qe9) | Open MthK pore structure soaked in 10 mM Ba2+/100 mM K+ | Descriptor: | Calcium-gated potassium channel MthK, POTASSIUM ION | Authors: | Guo, R, Zeng, W, Cui, H, Chen, L, Ye, S. | Deposit date: | 2014-05-15 | Release date: | 2014-07-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Ionic interactions of Ba2+ blockades in the MthK K+ channel J.Gen.Physiol., 144, 2014
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4RF6
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![BU of 4rf6 by Molmil](/molmil-images/mine/4rf6) | Crystal structure of double-domain arginine kinase from Anthopleura japonicas | Descriptor: | Arginine kinase | Authors: | Wang, Z, Qiao, Z, Ye, S, Zhang, R. | Deposit date: | 2014-09-25 | Release date: | 2015-04-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of a double-domain phosphagen kinase reveals an asymmetric arrangement of the tandem domains. Acta Crystallogr.,Sect.D, 71, 2015
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