8PZ1
 
 | | Wait Complex: Lateral open BAM bound Compact SurA | | Descriptor: | Chaperone SurA, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | | Authors: | Fenn, K.L, Ranson, N.A. | | Deposit date: | 2023-07-26 | | Release date: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Outer membrane protein assembly mediated by BAM-SurA complexes.
Nat Commun, 15, 2024
|
|
8Q0G
 | | Release Complex: BAM bound EspP and Compact SurA | | Descriptor: | Chaperone SurA, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | | Authors: | Fenn, K.L, Ranson, N.A. | | Deposit date: | 2023-07-28 | | Release date: | 2024-10-02 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Outer membrane protein assembly mediated by BAM-SurA complexes.
Nat Commun, 15, 2024
|
|
9GZP
 | | WT-IAPP cryo-EM structure Type LL - control reaction | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Taylor, A.I.P, Xu, Y, Chakraborty, P, Brinkworth, A, Willis, L.F, Zhuravleva, A, Ranson, N.A, Foster, R, Radford, S.E. | | Deposit date: | 2024-10-04 | | Release date: | 2025-03-05 | | Last modified: | 2025-04-16 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Kinetic Steering of Amyloid Formation and Polymorphism by Canagliflozin, a Type-2 Diabetes Drug.
J.Am.Chem.Soc., 147, 2025
|
|
9GZY
 | | WT-IAPP cryo-EM structure Type LLUU, doxazosin reaction | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Taylor, A.I.P, Xu, Y, Chakraborty, P, Brinkworth, A, Willis, L.F, Zhuravleva, A, Ranson, N.A, Foster, R, Radford, S.E. | | Deposit date: | 2024-10-04 | | Release date: | 2025-03-05 | | Last modified: | 2025-04-16 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Kinetic Steering of Amyloid Formation and Polymorphism by Canagliflozin, a Type-2 Diabetes Drug.
J.Am.Chem.Soc., 147, 2025
|
|
9GZW
 | | WT-IAPP cryo-EM structure Type LL, doxazosin reaction | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Taylor, A.I.P, Xu, Y, Chakraborty, P, Brinkworth, A, Willis, L.F, Zhuravleva, A, Ranson, N.A, Foster, R, Radford, S.E. | | Deposit date: | 2024-10-04 | | Release date: | 2025-03-05 | | Last modified: | 2025-04-16 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Kinetic Steering of Amyloid Formation and Polymorphism by Canagliflozin, a Type-2 Diabetes Drug.
J.Am.Chem.Soc., 147, 2025
|
|
9GZ6
 | | WT-IAPP cryo-EM structure Type SS - control reaction | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Taylor, A.I.P, Xu, Y, Chakraborty, P, Brinkworth, A, Willis, L.F, Zhuravleva, A, Ranson, N.A, Foster, R, Radford, S.E. | | Deposit date: | 2024-10-03 | | Release date: | 2025-03-05 | | Last modified: | 2025-04-16 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Kinetic Steering of Amyloid Formation and Polymorphism by Canagliflozin, a Type-2 Diabetes Drug.
J.Am.Chem.Soc., 147, 2025
|
|
9GZS
 | | WT-IAPP cryo-EM structure Type LLU - control reaction | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Taylor, A.I.P, Xu, Y, Chakraborty, P, Brinkworth, A, Willis, L.F, Zhuravleva, A, Ranson, N.A, Foster, R, Radford, S.E. | | Deposit date: | 2024-10-04 | | Release date: | 2025-03-05 | | Last modified: | 2025-04-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Kinetic Steering of Amyloid Formation and Polymorphism by Canagliflozin, a Type-2 Diabetes Drug.
J.Am.Chem.Soc., 147, 2025
|
|
9GZX
 | | WT-IAPP cryo-EM structure Type LLU, doxazosin reaction | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Taylor, A.I.P, Xu, Y, Chakraborty, P, Brinkworth, A, Willis, L.F, Zhuravleva, A, Ranson, N.A, Foster, R, Radford, S.E. | | Deposit date: | 2024-10-04 | | Release date: | 2025-03-05 | | Last modified: | 2025-04-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Kinetic Steering of Amyloid Formation and Polymorphism by Canagliflozin, a Type-2 Diabetes Drug.
J.Am.Chem.Soc., 147, 2025
|
|
9FWF
 | | N-VelcroVax HBcAg with SUMO-Affimer inserted at N-terminus (T=4 VLP) | | Descriptor: | N-VelcroVax HBcAg with SUMO-Affimer inserted at N-terminus | | Authors: | Fatema, K, Snowden, J.S, Watson, A, Sherry, L, Ranson, N.A, Stonehouse, N.J, Rowlands, D.J. | | Deposit date: | 2024-06-30 | | Release date: | 2025-02-26 | | Last modified: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | A VLP vaccine platform comprising the core protein of hepatitis B virus with N-terminal antigen capture.
Int.J.Biol.Macromol., 305, 2025
|
|
9FWE
 | | N-VelcroVax HBcAg with SUMO-Affimer inserted at N-terminus (T=3 VLP) | | Descriptor: | N-VelcroVax HBcAg with SUMO-Affimer inserted at N-terminus | | Authors: | Fatema, K, Snowden, J.S, Watson, A, Sherry, L, Ranson, N.A, Stonehouse, N.J, Rowlands, D.J. | | Deposit date: | 2024-06-30 | | Release date: | 2025-02-26 | | Last modified: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | A VLP vaccine platform comprising the core protein of hepatitis B virus with N-terminal antigen capture.
Int.J.Biol.Macromol., 305, 2025
|
|
9GZT
 | | WT-IAPP cryo-EM structure Type LLUU - control reaction | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Taylor, A.I.P, Xu, Y, Chakraborty, P, Brinkworth, A, Willis, L.F, Zhuravleva, A, Ranson, N.A, Foster, R, Radford, S.E. | | Deposit date: | 2024-10-04 | | Release date: | 2025-03-05 | | Last modified: | 2025-04-16 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Kinetic Steering of Amyloid Formation and Polymorphism by Canagliflozin, a Type-2 Diabetes Drug.
J.Am.Chem.Soc., 147, 2025
|
|
8BFB
 | | Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure (Methoxy-X04-labelled mice) | | Descriptor: | Amyloid-beta precursor protein | | Authors: | Wilkinson, M, Leistner, C, Burgess, A, Goodfellow, S, Deuchars, S, Ranson, N.A, Radford, S.E, Frank, R.A.W. | | Deposit date: | 2022-10-24 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The in-tissue molecular architecture of beta-amyloid pathology in the mammalian brain.
Nat Commun, 14, 2023
|
|
8BFA
 | | Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure | | Descriptor: | Amyloid-beta precursor protein | | Authors: | Wilkinson, M, Leistner, C, Burgess, A, Goodfellow, S, Deuchars, S, Ranson, N.A, Radford, S.E, Frank, R.A.W. | | Deposit date: | 2022-10-24 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The in-tissue molecular architecture of beta-amyloid pathology in the mammalian brain.
Nat Commun, 14, 2023
|
|
8AWT
 | | IAPP S20G lag-phase fibril polymorph 2PF-P | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-08-30 | | Release date: | 2024-01-10 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
|
|
8AZ3
 | | IAPP S20G growth-phase fibril polymorph 4PF-CU | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-09-05 | | Release date: | 2024-01-10 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
|
|
8AZ5
 | | IAPP S20G plateau-phase fibril polymorph 4PF-CU | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-09-05 | | Release date: | 2024-01-10 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
|
|
8AZ7
 | | IAPP S20G plateau-phase fibril polymorph 4PF-LJ | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-09-05 | | Release date: | 2024-01-10 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
|
|
8AZ0
 | | IAPP S20G growth-phase fibril polymorph 2PF-L | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-09-05 | | Release date: | 2024-01-10 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
|
|
8AZ1
 | | IAPP S20G growth-phase fibril polymorph 2PF-C | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-09-05 | | Release date: | 2024-01-10 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
|
|
8AZ2
 | | IAPP S20G growth-phase fibril polymorph 3PF-CU | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-09-05 | | Release date: | 2024-01-10 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
|
|
8AZ4
 | | IAPP S20G plateau-phase fibril polymorph 2PF-L | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-09-05 | | Release date: | 2024-01-10 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
|
|
8AZ6
 | | IAPP S20G plateau-phase fibril polymorph 4PF-LU | | Descriptor: | Islet amyloid polypeptide | | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-09-05 | | Release date: | 2024-01-10 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023
|
|
8BVQ
 | | E. coli BAM complex (BamABCDE) bound to darobactin B | | Descriptor: | Darobactin-B, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | | Authors: | Horne, J.E, Fenn, K.L, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-12-05 | | Release date: | 2023-05-24 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex in E. coli Cells.
Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
8BWC
 | | E. coli BAM complex (BamABCDE) wild-type | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Machin, J.M, Radford, S.E, Ranson, N.A. | | Deposit date: | 2022-12-06 | | Release date: | 2023-05-24 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex in E. coli Cells.
Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
8A7O
 | |
