7XQF
| Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE/CHS nanodiscs | Descriptor: | CHOLESTEROL HEMISUCCINATE, Gap junction alpha-1 protein, PHOSPHATIDYLETHANOLAMINE, ... | Authors: | Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. | Deposit date: | 2022-05-07 | Release date: | 2023-02-22 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14, 2023
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7XQD
| Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE/CHS nanodiscs (C1 symmetry) | Descriptor: | CHOLESTEROL HEMISUCCINATE, Gap junction alpha-1 protein, PHOSPHATIDYLETHANOLAMINE, ... | Authors: | Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. | Deposit date: | 2022-05-07 | Release date: | 2023-02-22 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14, 2023
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7XNH
| Human Cx36/GJD2 gap junction channel with pore-lining N-terminal helices in soybean lipids | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-28 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XKI
| Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (D6 symmetry) | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein,Soluble cytochrome b562 | Authors: | Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H. | Deposit date: | 2022-04-19 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XL8
| Human Cx36/GJD2 (N-terminal deletion mutant) gap junction channel in soybean lipids (D6 symmetry) | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-21 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XKK
| Human Cx36/GJD2 gap junction channel in detergents | Descriptor: | Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-19 | Release date: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XNV
| Structurally hetero-junctional human Cx36/GJD2 gap junction channel in soybean lipids (C6 symmetry) | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein | Authors: | Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S. | Deposit date: | 2022-04-29 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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7XKT
| Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H. | Deposit date: | 2022-04-20 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel. Nat Commun, 14, 2023
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6L3T
| Human Cx31.3/GJC3 connexin hemichannel in the absence of calcium | Descriptor: | Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol | Authors: | Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. | Deposit date: | 2019-10-15 | Release date: | 2020-09-09 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.34 Å) | Cite: | Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Sci Adv, 6, 2020
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6L3V
| The R15G mutant of human Cx31.3/GJC3 connexin hemichannel | Descriptor: | Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol | Authors: | Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. | Deposit date: | 2019-10-15 | Release date: | 2020-09-09 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.63 Å) | Cite: | Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Sci Adv, 6, 2020
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6L3U
| Human Cx31.3/GJC3 connexin hemichannel in the presence of calcium | Descriptor: | CALCIUM ION, Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol | Authors: | Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. | Deposit date: | 2019-10-15 | Release date: | 2020-09-09 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel. Sci Adv, 6, 2020
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4GOS
| Crystal structure of human B7-H4 IgV-like domain | Descriptor: | V-set domain-containing T-cell activation inhibitor 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Vigdorovich, V, Ramagopal, U, Bhosle, R, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | Deposit date: | 2012-08-20 | Release date: | 2012-09-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structure and cancer immunotherapy of the B7 family member B7x. Cell Rep, 9, 2014
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3BWE
| Crystal structure of aggregated form of DJ1 | Descriptor: | PHOSPHATE ION, Protein DJ-1 | Authors: | Cha, S.S. | Deposit date: | 2008-01-09 | Release date: | 2008-10-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of filamentous aggregates of human DJ-1 formed in an inorganic phosphate-dependent manner. J.Biol.Chem., 283, 2008
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5J45
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8GUW
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4DW6
| Novel N-phenyl-phenoxyacetamide derivatives as potential EthR inhibitors and ethionamide boosters. Discovery and optimization using High-Throughput Synthesis. | Descriptor: | AMMONIUM ION, GLYCEROL, HTH-type transcriptional regulator EthR, ... | Authors: | Flipo, M, Willand, N, Lecat-Guillet, N, Hounsou, C, Desroses, M, Leroux, F, Lens, Z, Villeret, V, Wohlkonig, A, Wintjens, R, Christophe, T, Jeon, H.K, Locht, C, Brodin, P, Baulard, A.R, Deprez, B. | Deposit date: | 2012-02-24 | Release date: | 2013-03-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis. J.Med.Chem., 55, 2012
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7VHV
| Crystal structure of S. aureus D-alanine alanyl carrier protein ligase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, D-alanine--D-alanyl carrier protein ligase, MAGNESIUM ION | Authors: | Lee, B.J, Lee, I.-G, Im, H.G, Yoon, H.J. | Deposit date: | 2021-09-23 | Release date: | 2022-04-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural and functional analysis of the D-alanyl carrier protein ligase DltA from Staphylococcus aureus Mu50. Acta Crystallogr D Struct Biol, 78, 2022
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3KTI
| Structure of ClpP in complex with ADEP1 | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide 1, ... | Authors: | Lee, B.-G, Brotz-Oesterhelt, H, Song, H.K. | Deposit date: | 2009-11-25 | Release date: | 2010-03-23 | Last modified: | 2013-02-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism Nat.Struct.Mol.Biol., 17, 2010
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3KTG
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3KTH
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3KTK
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3KTJ
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6PP9
| Crystal structure of BRAF:MEK1 complex | Descriptor: | 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, CHLORIDE ION, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Li, K, Gonzalez Del-Pino, G, Park, E, Eck, M.J. | Deposit date: | 2019-07-05 | Release date: | 2019-10-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575, 2019
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3ZTH
| Crystal structure of Stu0660 of Streptococcus thermophilus | Descriptor: | MAGNESIUM ION, STU0660 | Authors: | Lee, K.-H, Robinson, H, Oh, B.-H. | Deposit date: | 2011-07-08 | Release date: | 2012-07-11 | Last modified: | 2012-10-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Identification, Structural, and Biochemical Characterization of a Group of Large Csn2 Proteins Involved in Crispr-Mediated Bacterial Immunity. Proteins, 80, 2012
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3FPP
| Crystal structure of E.coli MacA | Descriptor: | Macrolide-specific efflux protein macA | Authors: | Yum, S, Xu, Y, Piao, S, Ha, N.-C. | Deposit date: | 2009-01-06 | Release date: | 2009-04-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Crystal structure of the periplasmic component of a tripartite macrolide-specific efflux pump J.Mol.Biol., 387, 2009
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