7XQF
Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE/CHS nanodiscs
Summary for 7XQF
Entry DOI | 10.2210/pdb7xqf/pdb |
EMDB information | 33394 |
Descriptor | Gap junction alpha-1 protein, TETRADECANE, PHOSPHATIDYLETHANOLAMINE, ... (5 entities in total) |
Functional Keywords | cx43, connexin, gap junction channel, gating mechanism, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 12 |
Total formula weight | 399435.67 |
Authors | |
Primary citation | Lee, H.J.,Cha, H.J.,Jeong, H.,Lee, S.N.,Lee, C.W.,Kim, M.,Yoo, J.,Woo, J.S. Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14:931-931, 2023 Cited by PubMed: 36805660DOI: 10.1038/s41467-023-36593-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.3 Å) |
Structure validation
Download full validation report