6PP9
Crystal structure of BRAF:MEK1 complex
Summary for 6PP9
Entry DOI | 10.2210/pdb6pp9/pdb |
Related | 6NYB |
Descriptor | Serine/threonine-protein kinase B-raf, Dual specificity mitogen-activated protein kinase kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (9 entities in total) |
Functional Keywords | braf, mek1, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 77756.75 |
Authors | Li, K.,Gonzalez Del-Pino, G.,Park, E.,Eck, M.J. (deposition date: 2019-07-05, release date: 2019-10-09, Last modification date: 2023-10-11) |
Primary citation | Park, E.,Rawson, S.,Li, K.,Kim, B.W.,Ficarro, S.B.,Pino, G.G.,Sharif, H.,Marto, J.A.,Jeon, H.,Eck, M.J. Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575:545-550, 2019 Cited by PubMed: 31581174DOI: 10.1038/s41586-019-1660-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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