6PP9

Crystal structure of BRAF:MEK1 complex

Summary for 6PP9

• Entry DOI: 10.2210/pdb6pp9/pdb
• Related: 6NYB
• Descriptor: Serine/threonine-protein kinase B-raf, Dual specificity mitogen-activated protein kinase kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (9 entities in total)
• Functional Keywords: braf, mek1, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 77756.75

Authors

Li, K.,Gonzalez Del-Pino, G.,Park, E.,Eck, M.J. (deposition date: 2019-07-05, release date: 2019-10-09, Last modification date: 2023-10-11)

• Primary citation: Park, E.,Rawson, S.,Li, K.,Kim, B.W.,Ficarro, S.B.,Pino, G.G.,Sharif, H.,Marto, J.A.,Jeon, H.,Eck, M.J.; Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.; Nature, 575:545-550, 2019; PubMed: 31581174; DOI: 10.1038/s41586-019-1660-y

Experimental method

X-RAY DIFFRACTION (2.59 Å)