7B1J
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4S1K
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![BU of 4s1k by Molmil](/molmil-images/mine/4s1k) | Structure of Uranotaenia sapphirina cypovirus (CPV17) polyhedrin at 100 K | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyhedrin | Authors: | Ginn, H.M, Messerschmidt, M, Ji, X, Zhang, H, Axford, D, Gildea, R.J, Winter, G, Brewster, A.S, Hattne, J, Wagner, A, Grimes, J.M, Evans, G, Sauter, N.K, Sutton, G, Stuart, D.I. | Deposit date: | 2015-01-14 | Release date: | 2015-03-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data. Nat Commun, 6, 2015
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4S1L
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![BU of 4s1l by Molmil](/molmil-images/mine/4s1l) | Structure of Uranotaenia sapphirina cypovirus (CPV17) polyhedrin at 298 K | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, polyhedrin | Authors: | Ginn, H.M, Messerschmidt, M, Ji, X, Zhang, H, Axford, D, Gildea, R.J, Winter, G, Brewster, A.S, Hattne, J, Wagner, A, Grimes, J.M, Evans, G, Sauter, N.K, Sutton, G, Stuart, D.I. | Deposit date: | 2015-01-14 | Release date: | 2015-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data. Nat Commun, 6, 2015
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4UI9
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![BU of 4ui9 by Molmil](/molmil-images/mine/4ui9) | Atomic structure of the human Anaphase-Promoting Complex | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | Authors: | Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | Deposit date: | 2015-03-27 | Release date: | 2015-06-17 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination Nature, 522, 2015
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6YPC
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![BU of 6ypc by Molmil](/molmil-images/mine/6ypc) | Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9 angstroms | Descriptor: | Inner kinetochore subunit CNN1, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, ... | Authors: | Bellini, D, Zhang, Z, Barford, D. | Deposit date: | 2020-04-15 | Release date: | 2020-09-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the Cenp-HIKHead-TW sub-module of the inner kinetochore CCAN complex. Nucleic Acids Res., 48, 2020
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2BGG
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![BU of 2bgg by Molmil](/molmil-images/mine/2bgg) | The structure of a Piwi protein from Archaeoglobus fulgidus complexed with a 16nt siRNA duplex. | Descriptor: | 5'-R(*GP*UP*CP*GP*AP*AP*UP*UP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ... | Authors: | Parker, J.S, Roe, S.M, Barford, D. | Deposit date: | 2004-12-22 | Release date: | 2005-03-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Insights Into Mrna Recognition from a Piwi Domain-Sirna Guide Complex Nature, 434, 2005
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8QV0
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![BU of 8qv0 by Molmil](/molmil-images/mine/8qv0) | Structure of the native microtubule lattice nucleated from the yeast spindle pole body | Descriptor: | Tubulin alpha-1 chain, Tubulin beta chain | Authors: | Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D. | Deposit date: | 2023-10-17 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Structure of the native gamma-tubulin ring complex capping spindle microtubules. Nat.Struct.Mol.Biol., 2024
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7YWX
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![BU of 7ywx by Molmil](/molmil-images/mine/7ywx) | Structure of the human CCAN CENP-A alpha-satellite complex | Descriptor: | Centromere protein C, Centromere protein H, Centromere protein I, ... | Authors: | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | Deposit date: | 2022-02-14 | Release date: | 2022-05-18 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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7YYH
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![BU of 7yyh by Molmil](/molmil-images/mine/7yyh) | Structure of the human CCANdeltaT CENP-A alpha-satellite complex | Descriptor: | Centromere protein C, Centromere protein H, Centromere protein I, ... | Authors: | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | Deposit date: | 2022-02-17 | Release date: | 2022-05-18 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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7R5S
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![BU of 7r5s by Molmil](/molmil-images/mine/7r5s) | Structure of the human CCAN bound to alpha satellite DNA | Descriptor: | Centromere protein H, Centromere protein I, Centromere protein K, ... | Authors: | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | Deposit date: | 2022-02-11 | Release date: | 2022-04-27 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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7R5R
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![BU of 7r5r by Molmil](/molmil-images/mine/7r5r) | Structure of the human CCAN CENP-A alpha-satellite complex | Descriptor: | Centromere protein C, DNA (171-MER), Histone H2A type 1-C, ... | Authors: | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | Deposit date: | 2022-02-11 | Release date: | 2022-04-27 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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7R5V
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![BU of 7r5v by Molmil](/molmil-images/mine/7r5v) | Structure of the human CCAN CENP-A alpha-satellite complex | Descriptor: | Centromere protein H, Centromere protein I, Centromere protein K, ... | Authors: | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | Deposit date: | 2022-02-11 | Release date: | 2022-04-27 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.55 Å) | Cite: | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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8QV3
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![BU of 8qv3 by Molmil](/molmil-images/mine/8qv3) | Structure of the y-Tubulin Small Complex (yTuSC) as part of the native y-Tubulin Ring Complex (yTuRC) capping microtubule minus ends at the spindle pole body | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component, Spindle pole body component 110, ... | Authors: | Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D. | Deposit date: | 2023-10-17 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Structure of the native gamma-tubulin ring complex capping spindle microtubules. Nat.Struct.Mol.Biol., 2024
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8QV2
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![BU of 8qv2 by Molmil](/molmil-images/mine/8qv2) | Structure of the native y-Tubulin Ring Complex (yTuRC) capping microtubule minus ends at the spindle pole body | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component, ... | Authors: | Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D. | Deposit date: | 2023-10-17 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (9.2 Å) | Cite: | Structure of the native gamma-tubulin ring complex capping spindle microtubules. Nat.Struct.Mol.Biol., 2024
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8QRY
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![BU of 8qry by Molmil](/molmil-images/mine/8qry) | |
8PPR
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![BU of 8ppr by Molmil](/molmil-images/mine/8ppr) | |
1BZC
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![BU of 1bzc by Molmil](/molmil-images/mine/1bzc) | HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH TPI | Descriptor: | 4-CARBAMOYL-4-{[6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBONYL]-AMINO}-BUTYRIC ACID, PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE) | Authors: | Groves, M.R, Yao, Z.J, Jr Burke, T.R, Barford, D. | Deposit date: | 1998-10-27 | Release date: | 1999-02-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics. Biochemistry, 37, 1998
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2W9N
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![BU of 2w9n by Molmil](/molmil-images/mine/2w9n) | crystal structure of linear di-ubiquitin | Descriptor: | CHLORIDE ION, UBIQUITIN, ZINC ION | Authors: | Komander, D, Reyes-Turcu, F, Wilkinson, K.D, Barford, D. | Deposit date: | 2009-01-27 | Release date: | 2009-04-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Molecular Discrimination of Structurally Equivalent Lys 63-Linked and Linear Polyubiquitin Chains. Embo Rep., 10, 2009
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2VFJ
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2V55
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![BU of 2v55 by Molmil](/molmil-images/mine/2v55) | Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Komander, D, Garg, R, Wan, P.T.C, Ridley, A.J, Barford, D. | Deposit date: | 2008-10-01 | Release date: | 2008-11-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.705 Å) | Cite: | Mechanism of Multi-Site Phosphorylation from a Rock-I:Rhoe Complex Structure. Embo J., 27, 2008
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2VHF
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![BU of 2vhf by Molmil](/molmil-images/mine/2vhf) | Structure of the CYLD USP domain | Descriptor: | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD, ZINC ION | Authors: | Komander, D, Lord, C.J, Scheel, H, Swift, S, Hofmann, K, Ashworth, A, Barford, D. | Deposit date: | 2007-11-21 | Release date: | 2008-03-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Structure of the Cyld Usp Domain Explains its Specificity for Lys63-Linked Polyubiquitin and Reveals a B-Box Module Mol.Cell.Biol., 29, 2008
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6QLE
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![BU of 6qle by Molmil](/molmil-images/mine/6qle) | Structure of inner kinetochore CCAN complex | Descriptor: | Central kinetochore subunit CTF3,Inner kinetochore subunit CTF3,Central kinetochore subunit CTF3,Inner kinetochore subunit CTF3, Central kinetochore subunit MCM16,Central kinetochore subunit MCM16,Inner kinetochore subunit MCM16,Mcm16p, Inner kinetochore subunit AME1,Inner kinetochore subunit AME1,Inner kinetochore subunit AME1,Inner kinetochore subunit AME1, ... | Authors: | Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. | Deposit date: | 2019-01-31 | Release date: | 2019-10-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome. Nature, 574, 2019
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6QLD
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![BU of 6qld by Molmil](/molmil-images/mine/6qld) | Structure of inner kinetochore CCAN-Cenp-A complex | Descriptor: | DNA (125-MER), Histone H2A.1, Histone H2B.1, ... | Authors: | Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. | Deposit date: | 2019-01-31 | Release date: | 2019-10-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome. Nature, 574, 2019
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1BZH
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![BU of 1bzh by Molmil](/molmil-images/mine/1bzh) | Cyclic peptide inhibitor of human PTP1B | Descriptor: | PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B INHIBITOR), PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B) | Authors: | Groves, M.R, Yao, Z.J, Burke Jr, T.R, Barford, D. | Deposit date: | 1998-10-28 | Release date: | 1999-02-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics. Biochemistry, 37, 1998
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6QLF
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![BU of 6qlf by Molmil](/molmil-images/mine/6qlf) | Structure of inner kinetochore CCAN complex with mask1 | Descriptor: | Inner kinetochore subunit AME1, Inner kinetochore subunit CHL4, Inner kinetochore subunit CTF19, ... | Authors: | Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D. | Deposit date: | 2019-01-31 | Release date: | 2019-10-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome. Nature, 574, 2019
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