7MF7
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![BU of 7mf7 by Molmil](/molmil-images/mine/7mf7) | Crystal structure of antibody 10E8v4-P100gA Fab | Descriptor: | Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain | Authors: | Kwon, Y.D, Kwong, P.D. | Deposit date: | 2021-04-08 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography. Antibodies, 10, 2021
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7MF9
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![BU of 7mf9 by Molmil](/molmil-images/mine/7mf9) | Crystal structure of antibody 10E8v4-P100fA Fab in space group C2 | Descriptor: | Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain | Authors: | Kwon, Y.D, Kwong, P.D. | Deposit date: | 2021-04-08 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography. Antibodies, 10, 2021
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7MF8
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![BU of 7mf8 by Molmil](/molmil-images/mine/7mf8) | Crystal structure of antibody 10E8v4-P100fA Fab in space group P6422 | Descriptor: | Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain | Authors: | Kwon, Y.D, Kwong, P.D. | Deposit date: | 2021-04-08 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography. Antibodies, 10, 2021
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6WWC
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![BU of 6wwc by Molmil](/molmil-images/mine/6wwc) | |
6WX2
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![BU of 6wx2 by Molmil](/molmil-images/mine/6wx2) | |
6XRT
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![BU of 6xrt by Molmil](/molmil-images/mine/6xrt) | |
6XCJ
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![BU of 6xcj by Molmil](/molmil-images/mine/6xcj) | Crystal Structure of DH650 Fab from a Rhesus Macaque in Complex with HIV-1 gp120 Core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH650 Fab Heavy Chain, DH650 Fab Light Chain, ... | Authors: | Raymond, D.D, Chug, H, Harrison, S.C. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science, 371, 2021
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8ELI
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![BU of 8eli by Molmil](/molmil-images/mine/8eli) | |
8EUV
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![BU of 8euv by Molmil](/molmil-images/mine/8euv) | Cryo-EM structure of HIV-1 BG505 DS-SOSIP ENV trimer bound to VRC34.01-COMBO1 FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Pletnev, S, Kwong, P. | Deposit date: | 2022-10-19 | Release date: | 2023-09-27 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site. Nat Commun, 14, 2023
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8EUW
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![BU of 8euw by Molmil](/molmil-images/mine/8euw) | Cryo-EM structure of HIV-1 BG505 DS-SOSIP ENV trimer bound to VRC34.01-MM28 FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Pletnev, S, Kwong, P. | Deposit date: | 2022-10-19 | Release date: | 2023-09-27 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site. Nat Commun, 14, 2023
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8EUU
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![BU of 8euu by Molmil](/molmil-images/mine/8euu) | Cryo-EM structure of HIV-1 BG505 DS-SOSIP ENV trimer bound to VRC34.01 FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Pletnev, S, Kwong, P. | Deposit date: | 2022-10-19 | Release date: | 2023-09-27 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site. Nat Commun, 14, 2023
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4YDK
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![BU of 4ydk by Molmil](/molmil-images/mine/4ydk) | Crystal structure of broadly and potently neutralizing antibody C38-VRC16.01 in complex with HIV-1 clade AE strain 93TH057 gp120 | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhou, T, Moquin, S, Zheng, A, Kwong, P.D. | Deposit date: | 2015-02-22 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.051 Å) | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell, 161, 2015
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4YDJ
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![BU of 4ydj by Molmil](/molmil-images/mine/4ydj) | Crystal structure of broadly and potently neutralizing antibody 44-VRC13.01 in complex with HIV-1 clade AE strain 93TH057 gp120 | Descriptor: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Zhou, T, Moquin, S, Kwong, P.D. | Deposit date: | 2015-02-22 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.308 Å) | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell, 161, 2015
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4YDL
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![BU of 4ydl by Molmil](/molmil-images/mine/4ydl) | Crystal structure of broadly and potently neutralizing antibody C38-VRC18.02 in complex with HIV-1 clade AE strain 93TH057gp120 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Envelope glycoprotein gp160,Envelope glycoprotein gp160, ... | Authors: | Zhou, T, Srivatsan, S, Kwong, P.D. | Deposit date: | 2015-02-22 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell, 161, 2015
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4YFL
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![BU of 4yfl by Molmil](/molmil-images/mine/4yfl) | Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 1B2530 in complex with HIV-1 clade A/E 93TH057 gp120 | Descriptor: | 1B2530 Light chain, 1B2530 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Acharya, P, Zhou, T, Moquin, S, Kwong, P.D. | Deposit date: | 2015-02-25 | Release date: | 2015-06-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.387 Å) | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell, 161, 2015
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4YE4
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![BU of 4ye4 by Molmil](/molmil-images/mine/4ye4) | Crystal Structure of Neutralizing Antibody HJ16 in Complex with HIV-1 gp120 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HT593.1 gp120, Heavy chain human antibody HJ16, ... | Authors: | Kwong, P.D, Chen, L, Zhou, T. | Deposit date: | 2015-02-23 | Release date: | 2015-07-22 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell, 161, 2015
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4ZMJ
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![BU of 4zmj by Molmil](/molmil-images/mine/4zmj) | Crystal Structure of Ligand-Free BG505 SOSIP.664 HIV-1 Env Trimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Kwon, Y.D, Kwong, P.D. | Deposit date: | 2015-05-04 | Release date: | 2015-06-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nat.Struct.Mol.Biol., 22, 2015
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4YDI
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![BU of 4ydi by Molmil](/molmil-images/mine/4ydi) | Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Zhou, T, Srivatsan, S, Kwong, P.D. | Deposit date: | 2015-02-22 | Release date: | 2015-06-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.452 Å) | Cite: | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell, 161, 2015
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6OKQ
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![BU of 6okq by Molmil](/molmil-images/mine/6okq) | Crystal structure of the SF12 Fab | Descriptor: | SF12 Fab Heavy Chain,SF12 Fab Heavy Chain, SF12 Fab Light Chain,SF12 Fab Light Chain | Authors: | Barnes, C.O, Bjorkman, P.J. | Deposit date: | 2019-04-14 | Release date: | 2019-06-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity, 50, 2019
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6OKP
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![BU of 6okp by Molmil](/molmil-images/mine/6okp) | B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074 | Descriptor: | 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Barnes, C.O, Bjorkman, P.J. | Deposit date: | 2019-04-14 | Release date: | 2019-06-05 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity, 50, 2019
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6OT1
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![BU of 6ot1 by Molmil](/molmil-images/mine/6ot1) | |
6OSY
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![BU of 6osy by Molmil](/molmil-images/mine/6osy) | |
6P62
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![BU of 6p62 by Molmil](/molmil-images/mine/6p62) | HIV Env BG505 NFL TD+ in complex with antibody E70 fragment antigen binding | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env BG505 NFL TD+, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2019-05-31 | Release date: | 2019-11-20 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019
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6PEH
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![BU of 6peh by Molmil](/molmil-images/mine/6peh) | Crystal structure of rabbit monoclonal anti-HIV antibody 1C2 | Descriptor: | 1C2 Fab Heavy Chain, 1C2 Fab Light Chain, SULFATE ION | Authors: | Liban, T, Pancera, M. | Deposit date: | 2019-06-20 | Release date: | 2019-11-20 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.296 Å) | Cite: | Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019
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6P65
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![BU of 6p65 by Molmil](/molmil-images/mine/6p65) | HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2019-05-31 | Release date: | 2019-11-20 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019
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