5JRC
 
 | |
5JR9
 | | Crystal structure of apo-NeC3PO | | Descriptor: | NEQ131 | | Authors: | Zhang, J, Gan, J. | | Deposit date: | 2016-05-06 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016
|
|
5J2Y
 | | Molecular insight into the regulatory mechanism of the quorum-sensing repressor RsaL in Pseudomonas aeruginosa | | Descriptor: | DNA (26-MER), Regulatory protein | | Authors: | Zhao, J, Gan, J, Zhang, J, Kang, H, Kong, W, Zhu, M, Li, F, Song, Y, Qin, J, Liang, H. | | Deposit date: | 2016-03-30 | | Release date: | 2017-04-12 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of Pseudomonas aeruginosa RsaL bound to promoter DNA reaffirms its role as a global regulator involved in quorum-sensing.
Nucleic Acids Res., 45, 2017
|
|
7ALN
 | | Cryo-EM structure of the divergent actomyosin complex from Plasmodium falciparum Myosin A in the Rigor state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... | | Authors: | Robert-Paganin, J, Xu, X.-P, Swift, M.F, Auguin, D, Robblee, J.P, Lu, H, Fagnant, P.M, Krementsova, E.B, Trybus, K.M, Houdusse, A, Volkmann, N, Hanein, D. | | Deposit date: | 2020-10-06 | | Release date: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (3.77 Å) | | Cite: | The actomyosin interface contains an evolutionary conserved core and an ancillary interface involved in specificity.
Nat Commun, 12, 2021
|
|
4QKN
 | | Crystal structure of FTO bound to a selective inhibitor | | Descriptor: | 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, GLYCEROL, ... | | Authors: | Yang, C.-G, Huang, Y, Gan, J. | | Deposit date: | 2014-06-07 | | Release date: | 2014-12-03 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5.
Nucleic Acids Res., 43, 2015
|
|
7V6K
 | | Crystal structure of Sortase A from Streptococcus pyogenes in complex with ML346 | | Descriptor: | 5-[3-(4-methoxyphenyl)prop-2-enylidene]-1,3-diazinane-2,4,6-trione, MAGNESIUM ION, Sortase | | Authors: | Yang, C.G, Gan, J. | | Deposit date: | 2021-08-20 | | Release date: | 2021-12-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella.
Rsc Med Chem, 13, 2022
|
|
3IFF
 | | 2'-SeMe-A modified DNA decamer | | Descriptor: | DNA (5'-D(*GP*TP*AP*CP*GP*CP*GP*TP*(XUA)P*C)-3'), MAGNESIUM ION | | Authors: | Sheng, J, Gan, J, Salon, J, Huang, Z. | | Deposit date: | 2009-07-24 | | Release date: | 2009-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Selenium modification at 2'-position of adenosine for nucleic acid structure studies
To be Published
|
|
3IFI
 | | 2'-SeMe-dG modified octamer DNA | | Descriptor: | DNA (5'-D(*GP*TP*(XUG)P*TP*AP*CP*AP*C)-3') | | Authors: | Sheng, J, Gan, J, Salon, J, Huang, Z. | | Deposit date: | 2009-07-24 | | Release date: | 2009-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Synthesis and crystal structure of 2'-se-modified guanosine containing DNA.
J.Org.Chem., 75, 2010
|
|
4R4X
 | | Structure of PNGF-II in C2 space group | | Descriptor: | PNGF-II, ZINC ION | | Authors: | Sun, G, Yu, X, Celimuge, Wang, L, Li, M, Gan, J, Qu, D, Ma, J, Chen, L. | | Deposit date: | 2014-08-20 | | Release date: | 2015-01-28 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Identification and
Characterization of a Novel Prokaryotic Peptide: N-glycosidase from
Elizabethkingia meningoseptica
J.Biol.Chem., 2015
|
|
4R4Z
 | | Structure of PNGF-II in P21 space group | | Descriptor: | PNGF-II | | Authors: | Sun, G, Yu, X, Celimuge, Wang, L, Li, M, Gan, J, Qu, D, Ma, J, Chen, L. | | Deposit date: | 2014-08-20 | | Release date: | 2015-01-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Identification and
Characterization of a Novel Prokaryotic Peptide: N-glycosidase from
Elizabethkingia meningoseptica
J.Biol.Chem., 2015
|
|
3IKI
 | | 5-SMe-dU containing DNA octamer | | Descriptor: | 5'-D(*GP*(UMS)P*GP*(US2)P*AP*CP*AP*C)-3', MAGNESIUM ION | | Authors: | Sheng, J, Hassan, A.E.A, Zhang, W, Gan, J, Huang, Z. | | Deposit date: | 2009-08-05 | | Release date: | 2010-03-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone.
Nucleic Acids Res., 40, 2012
|
|
3IJN
 | |
4MSR
 | | RNA 10mer duplex with six 2'-5'-linkages | | Descriptor: | RNA 10mer duplex with six 2'-5'-linkages, STRONTIUM ION | | Authors: | Sheng, J, Li, L, Engelhart, A.E, Gan, J, Wang, J, Szostak, J.W. | | Deposit date: | 2013-09-18 | | Release date: | 2014-02-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structural insights into the effects of 2'-5' linkages on the RNA duplex.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4MS9
 | | Native RNA-10mer Structure: ccggcgccgg | | Descriptor: | Native RNA duplex 10mer, STRONTIUM ION | | Authors: | Sheng, J, Li, L, Engelhart, A.E, Gan, J, Wang, J, Szostak, J.W. | | Deposit date: | 2013-09-18 | | Release date: | 2014-02-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.32 Å) | | Cite: | Structural insights into the effects of 2'-5' linkages on the RNA duplex.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4MSB
 | | RNA 10mer duplex with two 2'-5'-linkages | | Descriptor: | RNA 10mer duplex with two 2'-5'-linkages, STRONTIUM ION | | Authors: | Sheng, J, Li, L, Engelhart, A.E, Gan, J, Wang, J, Szostak, J.W. | | Deposit date: | 2013-09-18 | | Release date: | 2014-02-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural insights into the effects of 2'-5' linkages on the RNA duplex.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4KW0
 | | Structure of Dickerson-Drew Dodecamer with 2'-MeSe-ara-G modification | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*(1TW)P*CP*G)-3'), MAGNESIUM ION | | Authors: | Jiang, S, Gan, J, Sheng, J, Sun, H, Huang, Z. | | Deposit date: | 2013-05-23 | | Release date: | 2013-07-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Structure of Dickerson-Drew Dodecamer with 2'-MeSe-ara-G modification
TO BE PUBLISHED
|
|
5ZYW
 | | The crystal structure of apo-HsMGME1 with Mn2+ | | Descriptor: | GLYCEROL, L(+)-TARTARIC ACID, MANGANESE (II) ION, ... | | Authors: | Yang, C, Gan, J. | | Deposit date: | 2018-05-28 | | Release date: | 2018-09-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural insights into DNA degradation by human mitochondrial nuclease MGME1
Nucleic Acids Res., 46, 2018
|
|
6AKW
 | | Crystal structure of RNA dioxygenase bound with an inhibitor | | Descriptor: | 2-OXOGLUTARIC ACID, 2-[[2,6-bis(chloranyl)-4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]amino]benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO | | Authors: | Yang, C.-G, Huang, Y, Gan, J. | | Deposit date: | 2018-09-04 | | Release date: | 2019-05-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
Cancer Cell, 35, 2019
|
|
4MG2
 | | ALKBH2 F102A cross-linked to undamaged dsDNA | | Descriptor: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA-1, DNA-2, ... | | Authors: | Chen, B, Gan, J, Yang, C.G. | | Deposit date: | 2013-08-28 | | Release date: | 2014-02-26 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The complex structures of ALKBH2 mutants cross-linked to
dsDNA reveal the conformational swing of β-hairpin
Sci China Chem, 57, 2014
|
|
4MGT
 | | ALKBH2 R110A cross-linked to undamaged dsDNA | | Descriptor: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA1, DNA2, ... | | Authors: | Chen, B, Gan, J, Yang, C.G. | | Deposit date: | 2013-08-28 | | Release date: | 2014-02-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The complex structures of ALKBH2 mutants cross-linked to
dsDNA reveal the conformational swing of β-hairpin
Sci China Chem, 57, 2014
|
|
4O0I
 | | Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with 2'-MeSe-arabino-guanosine derivatized DNA | | Descriptor: | 5'-D(*C*(1TW)P*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', DNA polymerase I, GLYCEROL, ... | | Authors: | Jiang, S, Gan, J, Sun, H, Huang, Z. | | Deposit date: | 2013-12-13 | | Release date: | 2014-12-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.203 Å) | | Cite: | Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with 2'-MeSe-arabino-guanosine derivatized DNA
TO BE PUBLISHED
|
|
5Z9X
 | | Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 in complex with an RNA substrate | | Descriptor: | MAGNESIUM ION, RNA (5'-R(P*GP*CP*CP*CP*AP*UP*UP*AP*G)-3'), SULFATE ION, ... | | Authors: | Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Gan, J, Cao, C, Huang, Y, Chen, X, Ma, J. | | Deposit date: | 2018-02-05 | | Release date: | 2018-06-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
|
|
5Z9Z
 | | The C-terminal RRM domain of Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 (E329A/E330A/E332A) | | Descriptor: | CITRATE ANION, Small RNA degrading nuclease 1 | | Authors: | Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Cao, C, Gan, J, Huang, Y, Chen, X, Ma, J. | | Deposit date: | 2018-02-05 | | Release date: | 2018-06-27 | | Last modified: | 2018-10-03 | | Method: | X-RAY DIFFRACTION (2.049 Å) | | Cite: | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
|
|
6BOG
 | | Crystal structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription | | Descriptor: | RNA polymerase-associated protein RapA, SULFATE ION | | Authors: | Shaw, G.X, Gan, J, Zhou, Y.N, Zhang, R, Joachimiak, A, Jin, D.J, Ji, X. | | Deposit date: | 2017-11-20 | | Release date: | 2017-12-13 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.205 Å) | | Cite: | Structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription.
Structure, 16, 2008
|
|
2AJ3
 | | Crystal Structure of a Cross-Reactive HIV-1 Neutralizing CD4-Binding Site Antibody Fab m18 | | Descriptor: | Fab m18, Heavy Chain, Light Chain, ... | | Authors: | Prabakaran, P, Gan, J, Wu, Y.Q, Zhang, M.Y, Dimitrov, D.S, Ji, X. | | Deposit date: | 2005-08-01 | | Release date: | 2006-03-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structural mimicry of CD4 by a cross-reactive HIV-1 neutralizing antibody with CDR-H2 and H3 containing unique motifs.
J.Mol.Biol., 357, 2006
|
|
