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1U2N
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BU of 1u2n by Molmil
Structure CBP TAZ1 Domain
Descriptor: CREB binding protein, ZINC ION
Authors:De Guzman, R.N, Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2004-07-19
Release date:2005-04-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding
Biochemistry, 44, 2005
1TOT
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ZZ Domain of CBP- a Novel Fold for a Protein Interaction Module
Descriptor: CREB-binding protein, ZINC ION
Authors:Legge, G.B, Martinez-Yamout, M.A, Hambly, D.M, Trinh, T, Dyson, H.J, Wright, P.E.
Deposit date:2004-06-15
Release date:2005-01-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:ZZ domain of CBP: an unusual zinc finger fold in a protein interaction module
J.Mol.Biol., 343, 2004
1XJH
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BU of 1xjh by Molmil
NMR structure of the redox switch domain of the E. coli Hsp33
Descriptor: 33 kDa chaperonin, ZINC ION
Authors:Won, H.S, Low, L.Y, De Guzman, R.N, Martinez-Yamout, M.A, Jakob, U, Dyson, H.J.
Deposit date:2004-09-23
Release date:2004-10-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The Zinc-dependent Redox Switch Domain of the Chaperone Hsp33 has a Novel Fold
J.Mol.Biol., 341, 2004
1ZU1
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BU of 1zu1 by Molmil
Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
Descriptor: RNA binding protein ZFa, ZINC ION
Authors:Moller, H.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2005-05-29
Release date:2005-09-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal zinc fingers of the Xenopus laevis double-stranded RNA-binding protein ZFa
J.Mol.Biol., 351, 2005
5VMY
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BU of 5vmy by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*CP*GP*CP*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2017-04-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
5VMW
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Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2017-04-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
2HDP
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BU of 2hdp by Molmil
Solution Structure of Hdm2 RING Finger Domain
Descriptor: Ubiquitin-protein ligase E3 Mdm2, ZINC ION
Authors:Kostic, M, Matt, T, Yamout-Martinez, M, Dyson, H.J, Wright, P.E.
Deposit date:2006-06-20
Release date:2006-11-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53.
J.Mol.Biol., 363, 2006
2JP9
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Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
Descriptor: DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DGP*DCP*DGP*DC)-3'), DNA (5'-D(P*DGP*DCP*DGP*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), Wilms tumor 1, ...
Authors:Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
Deposit date:2007-04-30
Release date:2007-10-30
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2JPA
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Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
Descriptor: DNA (5'-D(P*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DG)-3'), Wilms tumor 1, ...
Authors:Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
Deposit date:2007-05-01
Release date:2007-10-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2KA4
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BU of 2ka4 by Molmil
NMR structure of the CBP-TAZ1/STAT2-TAD complex
Descriptor: Crebbp protein, Signal transducer and activator of transcription 2, ZINC ION
Authors:Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2008-10-30
Release date:2009-04-21
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains
Embo J., 28, 2009
2KA6
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BU of 2ka6 by Molmil
NMR structure of the CBP-TAZ2/STAT1-TAD complex
Descriptor: CREB-binding protein, Signal transducer and activator of transcription 1-alpha/beta, ZINC ION
Authors:Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2008-10-30
Release date:2009-04-07
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains.
Embo J., 28, 2009
2L14
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BU of 2l14 by Molmil
Structure of CBP nuclear coactivator binding domain in complex with p53 TAD
Descriptor: CREB-binding protein, Cellular tumor antigen p53
Authors:Lee, C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2010-07-22
Release date:2010-11-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.
Biochemistry, 49, 2010
2M9F
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BU of 2m9f by Molmil
NMR solution structure of Pin1 WW domain mutant 5-1g
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
Deposit date:2013-06-07
Release date:2013-06-26
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9E
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BU of 2m9e by Molmil
NMR solution structure of Pin1 WW domain mutant 5-1
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
Deposit date:2013-06-07
Release date:2013-06-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9J
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BU of 2m9j by Molmil
NMR solution structure of Pin1 WW domain mutant 6-1g
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
Deposit date:2013-06-10
Release date:2013-06-26
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9I
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BU of 2m9i by Molmil
NMR solution structure of Pin1 WW domain variant 6-1
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
Deposit date:2013-06-10
Release date:2013-06-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
8W1N
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BU of 8w1n by Molmil
Structure of transthyretin pathogenic mutation A120S
Descriptor: Transthyretin
Authors:Ferguson, J.A, Stanfield, R.L, Wright, P.E.
Deposit date:2024-02-16
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin
To Be Published
8W2W
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BU of 8w2w by Molmil
Structure of transthyretin synthetic mutation A120L
Descriptor: Transthyretin
Authors:Yang, K, Sun, X, Ferguson, J.A, Stanfield, R.L, Wright, P.E.
Deposit date:2024-02-21
Release date:2024-02-28
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin
To Be Published
2NC4
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BU of 2nc4 by Molmil
Solution Structure of N-Galactosylated Pin1 WW Domain
Descriptor: Pin1 WW Domain, beta-D-galactopyranose
Authors:Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
2NC6
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BU of 2nc6 by Molmil
Solution Structure of N-L-idosylated Pin1 WW Domain
Descriptor: Pin1 WW Domain, beta-L-idopyranose
Authors:Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
2NC3
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BU of 2nc3 by Molmil
Solution Structure of N-Allosylated Pin1 WW Domain
Descriptor: Pin1 WW Domain, beta-D-allopyranose
Authors:Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
1AI1
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BU of 1ai1 by Molmil
HIV-1 V3 LOOP MIMIC
Descriptor: AIB142, IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), IGG1-KAPPA 59.1 FAB (LIGHT CHAIN)
Authors:Ghiara, J.B, Wilson, I.A.
Deposit date:1996-11-06
Release date:1997-05-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site.
J.Mol.Biol., 266, 1997
5CC9
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BU of 5cc9 by Molmil
L28F E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
Descriptor: 5,10-DIDEAZATETRAHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Oyen, D, Wright, P.E.
Deposit date:2015-07-01
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
5CCC
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BU of 5ccc by Molmil
wild-type E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
Descriptor: 5,10-DIDEAZATETRAHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Oyen, D, Wright, P.E.
Deposit date:2015-07-01
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
8ECZ
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BU of 8ecz by Molmil
Bovine Fab 4C1
Descriptor: 4C1 Fab heavy chain, 4C1 Fab light chain, PHOSPHATE ION
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2022-09-02
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023

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数据于2024-05-29公开中

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