6QDU
| Crystal structure of 14-3-3sigma in complex with a RapGef2 pT740 phosphopeptide inhibited by semi-synthetic fusicoccane FC-NCPC | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, FC-NCPC, ... | Authors: | Andrei, S.A, Kaplan, A, Fournier, A.E, Ottman, C. | Deposit date: | 2019-01-02 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.632 Å) | Cite: | Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth. Cell Chem Biol, 27, 2020
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8GCC
| T. cruzi topoisomerase II alpha bound to dsDNA and the covalent inhibitor CT1 | Descriptor: | 2-{3-[(Z)-iminomethyl]-1H-1,2,4-triazol-1-yl}-1-{(3M)-3-[2-(trifluoromethyl)phenyl]-6H-pyrrolo[3,4-b]pyridin-6-yl}ethan-1-one, DNA (28-MER), DNA topoisomerase 2 | Authors: | Schenk, A, Deniston, C, Noeske, J. | Deposit date: | 2023-03-01 | Release date: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380, 2023
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2R9G
| Crystal structure of the C-terminal fragment of AAA ATPase from Enterococcus faecium | Descriptor: | AAA ATPase, central region, ACETATE ION, ... | Authors: | Ramagopal, U.A, Patskovsky, Y, Bonanno, J.B, Shi, W, Toro, R, Meyer, A.J, Rutter, M, Wu, B, Groshong, C, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-09-12 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystal Structure of the C-Terminal Domain of AAA ATPase from Enterococcus faecium. To be Published
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7N8D
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7N57
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7N4O
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7RZZ
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7N8G
| Crystal structure of R20A-R22A human Galectin-7 mutant | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | Authors: | Pham, N.T.H, Calmettes, C, Doucet, N. | Deposit date: | 2021-06-14 | Release date: | 2023-01-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of R20A human Galectin-7 mutant To Be Published
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2RJI
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2REJ
| ABC-transporter choline binding protein in unliganded semi-closed conformation | Descriptor: | PUTATIVE GLYCINE BETAINE ABC TRANSPORTER PROTEIN | Authors: | Oswald, C, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Le Rudulier, D, Schmitt, L, Bremer, E. | Deposit date: | 2007-09-26 | Release date: | 2008-09-16 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states. J.Biol.Chem., 283, 2008
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2RKW
| Intermediate position of ATP on its trail to the binding pocket inside the subunit B mutant R416W of the energy converter A1Ao ATP synthase | Descriptor: | V-type ATP synthase beta chain | Authors: | Kumar, A, Manimekalai, M.S.S, Balakrishna, A.M, Hunke, C, Gruber, G. | Deposit date: | 2007-10-18 | Release date: | 2008-09-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Spectroscopic and crystallographic studies of the mutant R416W give insight into the nucleotide binding traits of subunit B of the A1Ao ATP synthase Proteins, 75, 2009
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2RPP
| Solution structure of Tandem zinc finger domain 12 in Muscleblind-like protein 2 | Descriptor: | Muscleblind-like protein 2, ZINC ION | Authors: | Abe, C, Dang, W, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-06-24 | Release date: | 2009-05-12 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RNA binding domain in the human muscleblind-like protein 2 Protein Sci., 18, 2009
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2RIO
| Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation of non-conventional splicing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, STRONTIUM ION, ... | Authors: | Lee, K.P, Dey, M, Neculai, D, Cao, C, Dever, T.E, Sicheri, F. | Deposit date: | 2007-10-12 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the dual enzyme ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. Cell(Cambridge,Mass.), 132, 2008
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2RQX
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2RR3
| Solution structure of the complex between human VAP-A MSP domain and human OSBP FFAT motif | Descriptor: | Oxysterol-binding protein 1, Vesicle-associated membrane protein-associated protein A | Authors: | Furuita, K, Jee, J, Fukada, H, Mishima, M, Kojima, C. | Deposit date: | 2010-03-09 | Release date: | 2010-03-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies J.Biol.Chem., 285, 2010
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4AVZ
| Tailspike protein mutant E372Q of E. coli bacteriophage HK620 | Descriptor: | TAIL SPIKE PROTEIN, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM | Authors: | Gohlke, U, Broeker, N.K, Mueller, J.J, Uetrecht, C, Heinemann, U, Seckler, R, Barbirz, S. | Deposit date: | 2012-05-30 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Single Amino Acid Exchange in Bacteriophage Hk620 Tailspike Protein Results in Thousand-Fold Increase of its Oligosaccharide Affinity. Glycobiology, 23, 2013
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7O2N
| Crystal structure of B. subtilis UGPase YngB | Descriptor: | Probable UTP--glucose-1-phosphate uridylyltransferase YngB | Authors: | Wu, C. | Deposit date: | 2021-03-30 | Release date: | 2021-04-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and Functional Characterisation of the Bacillus subtilis Uridylyltransferase YngB Ph.D.Thesis, 2021
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7NZ7
| Crystal structure of mouse ADAT2/ADAT3 tRNA deamination complex 1 | Descriptor: | Probable inactive tRNA-specific adenosine deaminase-like protein 3, ZINC ION, tRNA-specific adenosine deaminase 2 | Authors: | Ramos Morales, E, Romier, C. | Deposit date: | 2021-03-23 | Release date: | 2021-05-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination. Nucleic Acids Res., 49, 2021
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7NZ9
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2RI1
| Crystal Structure of glucosamine 6-phosphate deaminase (NagB) with GlcN6P from S. mutans | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, Glucosamine-6-phosphate deaminase | Authors: | Liu, C, Li, D, Su, X.D. | Deposit date: | 2007-10-10 | Release date: | 2008-03-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Ring-opening mechanism revealed by crystal structures of NagB and its ES intermediate complex J.Mol.Biol., 379, 2008
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7NZ8
| Crystal structure of mouse ADAT2/ADAT3 tRNA deamination complex 2 | Descriptor: | Probable inactive tRNA-specific adenosine deaminase-like protein 3, ZINC ION, tRNA-specific adenosine deaminase 2 | Authors: | Ramos Morales, E, Romier, C. | Deposit date: | 2021-03-23 | Release date: | 2021-05-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination. Nucleic Acids Res., 49, 2021
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2RGB
| Crystal structure of H-RasQ61K-GppNHp | Descriptor: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | Authors: | Buhrman, G, Wink, G, Mattos, C. | Deposit date: | 2007-10-03 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf. Structure, 15, 2007
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2RGG
| Crystal structure of H-RasQ61I-GppNHp, trigonal crystal form | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Buhrman, G, Wink, G, Mattos, C. | Deposit date: | 2007-10-03 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf. Structure, 15, 2007
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7OEV
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7O0K
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