4U7D

Structure of human RECQ-like helicase in complex with an oligonucleotide

Summary for 4U7D

• Entry DOI: 10.2210/pdb4u7d/pdb
• Descriptor: ATP-dependent DNA helicase Q1, DNA oligonucleotide, ZINC ION (3 entities in total)
• Functional Keywords: hydrolase-dna complex, nuclear protein, hydrolase, dna strand annealing, dna binding protein, structural genomics, structural genomics consortium, sgc, hydrolase/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : P46063
• Total number of polymer chains: 8
• Total formula weight: 294069.04

Authors

Pike, A.C.W.,Zhang, Y.,Schnecke, C.,Cooper, C.D.O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O.,Structural Genomics Consortium (SGC) (deposition date: 2014-07-30, release date: 2015-01-21, Last modification date: 2023-12-20)

• Primary citation: Pike, A.C.,Gomathinayagam, S.,Swuec, P.,Berti, M.,Zhang, Y.,Schnecke, C.,Marino, F.,von Delft, F.,Renault, L.,Costa, A.,Gileadi, O.,Vindigni, A.; Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures.; Proc.Natl.Acad.Sci.USA, 112:4286-4291, 2015; PubMed: 25831490; DOI: 10.1073/pnas.1417594112

Experimental method

X-RAY DIFFRACTION (3.4 Å)