4U7D

Structure of human RECQ-like helicase in complex with an oligonucleotide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	ATP-dependent DNA helicase Q1	polymer	591	67415.0	4	UniProt (P46063) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124)	Homo sapiens (Human)	DNA helicase,RecQ-like type 1,RecQ1,DNA-dependent ATPase Q1,RecQ protein-like 1
2	E, F, G, H (P, Q, R, S)	DNA oligonucleotide	polymer	20	6036.9	4		synthetic construct
3	I, J, K, L (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)

Sequence modifications

A, B, C, D: 49 - 616 (UniProt: P46063)

PDB	External Database	Details
Met 48	-	initiating methionine
Ser 611	Gly 611	conflict
Ala 617	-	expression tag
Glu 618	-	expression tag
Asn 619	-	expression tag
Leu 620	-	expression tag
Tyr 621	-	expression tag
Phe 622	-	expression tag
Gln 623	-	expression tag
Ser 624	-	expression tag
His 625	-	expression tag
His 626	-	expression tag
His 627	-	expression tag
His 628	-	expression tag
His 629	-	expression tag
His 630	-	expression tag
Asp 631	-	expression tag
Tyr 632	-	expression tag
Lys 633	-	expression tag
Asp 634	-	expression tag
Asp 635	-	expression tag
Asp 636	-	expression tag
Asp 637	-	expression tag
Lys 638	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	293807.4
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	294069.0

*Water molecules are not included.