7FIO
LecA from Pseudomonas aeruginosa in complex with a synthetic monovalent galactosidic inhibitor
Summary for 7FIO
Entry DOI | 10.2210/pdb7fio/pdb |
Descriptor | PA-I galactophilic lectin, CALCIUM ION, N-[2-[4-[(2S)-3-(2-hydroxyethylamino)-3-oxidanylidene-2-(2-phenoxyethanoylamino)propyl]-1,2,3-triazol-1-yl]ethyl]-4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanyl-benzamide, ... (5 entities in total) |
Functional Keywords | lectin, carbohydrates, glycoconjugate, glycomimetics, leca, sugar binding protein |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 4 |
Total formula weight | 54125.95 |
Authors | Kuhaudomlarp, S.,Siebs, E.,da Silva Figueiredo Celestino Gomes, P.,Fortin, C.,Rognan, D.,Rademacher, C.,Imberty, A.,Titz, A. (deposition date: 2021-07-31, release date: 2022-02-16, Last modification date: 2023-11-29) |
Primary citation | Siebs, E.,Shanina, E.,Kuhaudomlarp, S.,da Silva Figueiredo Celestino Gomes, P.,Fortin, C.,Seeberger, P.H.,Rognan, D.,Rademacher, C.,Imberty, A.,Titz, A. Targeting the Central Pocket of the Pseudomonas aeruginosa Lectin LecA. Chembiochem, 23:e202100563-e202100563, 2022 Cited by PubMed: 34788491DOI: 10.1002/cbic.202100563 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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