Search by PDB author

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
Descriptor:	KWOCA_65
Authors:	Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
Deposit date:	2022-11-29
Release date:	2023-03-22
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (3.15 Å)
Cite:	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023

8FBN

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
Descriptor:	KWOCA_73
Authors:	Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
Deposit date:	2022-11-29
Release date:	2023-03-22
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (3.04 Å)
Cite:	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023

8FEG

CryoEM structure of Kappa Opioid Receptor bound to a semi-peptide and Gi1
Descriptor:	ACE-TYR-ALA-DTY-THR-THR-CYS-THR-DPN-XT9, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:	Fay, J.F, Che, T.
Deposit date:	2022-12-06
Release date:	2023-12-06
Last modified:	2025-06-04
Method:	ELECTRON MICROSCOPY (2.54 Å)
Cite:	Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor. Nat Commun, 14, 2023

3B5L

Crystal Structure of a Novel Engineered Retroaldolase: RA-61
Descriptor:	AMMONIUM ION, Endoxylanase, SULFATE ION
Authors:	Stoddard, B.L, Doyle, L.A.
Deposit date:	2007-10-26
Release date:	2008-01-22
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	De novo computational design of retro-aldol enzymes. Science, 319, 2008

8G4K

Complex of TbRII mini protein binder bound to the TbRII ECD
Descriptor:	5HCS_TGFBR2_1, SULFATE ION, TGF-beta receptor type-2
Authors:	Schwartze, T.S, Hinck, A.P.
Deposit date:	2023-02-09
Release date:	2024-08-14
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (1.24 Å)
Cite:	Computational Design of High Affinity Binders to Convex Protein Target Sites To be Published

7KNA

Localized reconstruction of the H1 A/Michigan/45/2015 ectodomain displayed at the surface of I53_dn5 nanoparticle
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,I53_dn5
Authors:	Acton, O.J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-11-04
Release date:	2021-03-31
Last modified:	2024-10-30
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Quadrivalent influenza nanoparticle vaccines induce broad protection. Nature, 592, 2021

5UN6

Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset
Descriptor:	Designed Wnt agonist B12, Frizzled-8
Authors:	Janda, C.Y, Garcia, K.C, Jude, K.M.
Deposit date:	2017-01-30
Release date:	2017-05-03
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling. Nature, 545, 2017

2LAF

NMR solution structure of the N-terminal domain of the E. coli lipoprotein BamC
Descriptor:	Lipoprotein 34
Authors:	Pardi, A, Warner, L.
Deposit date:	2011-03-11
Release date:	2011-06-01
Last modified:	2024-05-01
Method:	SOLUTION NMR
Cite:	Structure of the BamC Two-Domain Protein Obtained by Rosetta with a Limited NMR Data Set. J.Mol.Biol., 411, 2011

5UN5

Frizzled-8 complex with designed surrogate Wnt agonist, crystal form 1
Descriptor:	Designed Wnt agonist B12, Frizzled-8
Authors:	Janda, C.Y, Garcia, K.C.
Deposit date:	2017-01-30
Release date:	2017-05-03
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (2.994 Å)
Cite:	Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling. Nature, 545, 2017

2LAE

NMR solution structure of the C-terminal domain of the E. coli lipoprotein BamC
Descriptor:	Lipoprotein 34
Authors:	Pardi, A, Warner, L.
Deposit date:	2011-03-11
Release date:	2011-06-01
Last modified:	2024-05-01
Method:	SOLUTION NMR
Cite:	Structure of the BamC Two-Domain Protein Obtained by Rosetta with a Limited NMR Data Set. J.Mol.Biol., 411, 2011

9DZE

Computationally Designed Bifaceted Protein Nanomaterial pD5-14
Descriptor:	pD5-14 A component, pD5-14 B component, pD5-14 C component, ...
Authors:	Carr, K.D, Borst, A.J, Weidle, C.
Deposit date:	2024-10-16
Release date:	2024-10-30
Last modified:	2024-11-13
Method:	ELECTRON MICROSCOPY (4.3 Å)
Cite:	Computational design of bifaceted protein nanomaterials with tailorable properties. Biorxiv, 2024

9FDG

Solution structure of a de novo designed 12-stranded transmembrane beta-barrel in LDAO micelles.
Descriptor:	TMB12sol9_3
Authors:	Muentener, T, Hiller, S.
Deposit date:	2024-05-17
Release date:	2024-10-16
Method:	SOLUTION NMR
Cite:	Sculpting conducting nanopore size and shape through de novo protein design. Science, 385, 2024

2RKX

The 3D structure of chain D, cyclase subunit of imidazoleglycerol_evolvedcerolphosphate synthase
Descriptor:	Cyclase subunit of imidazoleglycerol_evolvedcerolphosphate synthase
Authors:	Tawfik, D, Khersonsky, O, Albeck, S, Dym, O, Israel Structural Proteomics Center (ISPC)
Deposit date:	2007-10-18
Release date:	2008-03-18
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Kemp elimination catalysts by computational enzyme design. Nature, 453, 2008

3HOJ

Crystal Structure of a Novel Engineered Retroaldolase: RA-22
Descriptor:	RETROALDOLASE-22
Authors:	Stoddard, B.L, Doyle, L.A.
Deposit date:	2009-06-02
Release date:	2009-08-25
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	De Novo Computational Design of Retro-Aldol Enzymes Science, 319, 2008

6DG4

Structure of the Chaetomium thermophilum Ulp1-like SUMO protease catalytic domain
Descriptor:	GLYCEROL, SULFATE ION, Ulp1-like SUMO protease
Authors:	Lima, C.D, Baytshtok, V.
Deposit date:	2018-05-16
Release date:	2018-07-11
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.442 Å)
Cite:	Discovery and engineering of enhanced SUMO protease enzymes. J. Biol. Chem., 293, 2018

7UBF

Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in 50% d6-DMSO and 50% water with cis/trans switching (CC conformation, 50%)
Descriptor:	Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU
Authors:	Ramelot, T.A, Tejero, R, Montelione, G.T.
Deposit date:	2022-03-14
Release date:	2022-09-14
Last modified:	2024-10-30
Method:	SOLUTION NMR
Cite:	Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022

7UBD

Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.31 in d6-DMSO with cis/trans switching (A-CC conformation)
Descriptor:	Cyclic peptide D8.31 DAL-DPR-MLU-DVA-DAL-DPR-MLU-DVA
Authors:	Ramelot, T.A, Tejero, R, Montelione, G.T.
Deposit date:	2022-03-14
Release date:	2022-09-14
Last modified:	2022-09-28
Method:	SOLUTION NMR
Cite:	Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022

7UBI

Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in CDCl3 with cis/trans switching (TT conformation, 47%)
Descriptor:	Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU
Authors:	Ramelot, T.A, Tejero, R, Montelione, G.T.
Deposit date:	2022-03-14
Release date:	2022-09-14
Last modified:	2024-11-13
Method:	SOLUTION NMR
Cite:	Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022

7UBC

Solution NMR structure of 9-residue Rosetta-designed cyclic peptide D9.16 in d6-DMSO with cis/trans switching
Descriptor:	Cyclic peptide D9.16 DPR-MAA-ALA-DVA-MLE-LEU-LEU-PRO-DLE
Authors:	Ramelot, T.A, Tejero, R, Monteltione, G.T.
Deposit date:	2022-03-14
Release date:	2022-09-14
Last modified:	2024-11-13
Method:	SOLUTION NMR
Cite:	Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022

7UBE

Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in d6-DMSO with cis/trans switching
Descriptor:	Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU
Authors:	Ramelot, T.A, Tejero, R, Montelione, G.T.
Deposit date:	2022-03-14
Release date:	2022-09-14
Last modified:	2024-11-13
Method:	SOLUTION NMR
Cite:	Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022

7UBG

Solution NMR structure of 9-residue Rosetta-designed cyclic peptide D9.16 in CDCl3 with cis/trans switching (A-TT conformation)
Descriptor:	Cyclic peptide D9.16 DPR-MAA-ALA-DVA-MLE-LEU-LEU-PRO-DLE
Authors:	Ramelot, T.A, Tejero, R, Montelione, G.T.
Deposit date:	2022-03-14
Release date:	2022-09-14
Last modified:	2024-10-30
Method:	SOLUTION NMR
Cite:	Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022

5VL4

Accidental minimum contact crystal lattice formed by a redesigned protein oligomer
Descriptor:	T33-53H-B
Authors:	Cannon, K.A, Cascio, D, Sawaya, M.R, Park, R, Boyken, S, King, N, Yeates, T.
Deposit date:	2017-04-24
Release date:	2018-05-23
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (4.1 Å)
Cite:	Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering. Protein Sci., 29, 2020

6Z2I

Crystal structure of DeNovoTIM6, a de novo designed TIM barrel
Descriptor:	de novo designed TIM barrel DeNovoTIM6
Authors:	Romero-Romero, S, Kordes, S, Shanmugaratnam, S, Rodriguez-Romero, A, Fernandez-Velasco, D.A, Hocker, B.
Deposit date:	2020-05-15
Release date:	2021-07-21
Last modified:	2024-05-01
Method:	X-RAY DIFFRACTION (2.901 Å)
Cite:	The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach. J.Mol.Biol., 433, 2021

6Z1K

A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.6
Descriptor:	1,2-ETHANEDIOL, BH32.6 protein, CALCIUM ION, ...
Authors:	Levy, C.W.
Deposit date:	2020-05-13
Release date:	2021-08-25
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.48 Å)
Cite:	Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction. Nat.Chem., 14, 2022

6Z1L

A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.12
Descriptor:	1,2-ETHANEDIOL, BH32.12 protein, PHOSPHATE ION
Authors:	Levy, C.W.
Deposit date:	2020-05-13
Release date:	2021-08-25
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.29 Å)
Cite:	Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction. Nat.Chem., 14, 2022

<18 19 20 21 22 23 24 25 26 27 282930 31 32 33 >

Total results:	818
Displayed results:	25
Sorted by:	Hit score (from highest)