8G4K

Complex of TbRII mini protein binder bound to the TbRII ECD

Summary for 8G4K

• Entry DOI: 10.2210/pdb8g4k/pdb
• Descriptor: 5HCS_TGFBR2_1, TGF-beta receptor type-2, SULFATE ION, ... (4 entities in total)
• Functional Keywords: tbrii, tgf-b type ii receptor, computationally designed mini protein binder, mpb, signaling protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 24360.07

Authors

Schwartze, T.S.,Hinck, A.P. (deposition date: 2023-02-09, release date: 2024-08-14, Last modification date: 2024-10-09)

• Primary citation: Yang, W.,Hicks, D.R.,Scwartze, T.A.,Ghosh, A.,Conventry, B.,Goreshnik, I.,Allen, A.,Halabiya, S.F.,Kim, C.J.,Hinck, C.S.,Lee, D.S.,Bera, A.K.,Li, Z.,Wang, Y.,Schlichthaerle, T.,Cao, L.,Huang, B.,Garrett, S.,Gerben, S.R.,Rettie, S.,Heine, P.,Murray, A.,Edman, N.,Carter, L.,Stewart, L.,Almo, S.,Hinck, A.P.,Baker, D.; Computational Design of High Affinity Binders to Convex Protein Target Sites; To be Published,

Experimental method

X-RAY DIFFRACTION (1.24 Å)