6Z2I

Crystal structure of DeNovoTIM6, a de novo designed TIM barrel

Summary for 6Z2I

• Entry DOI: 10.2210/pdb6z2i/pdb
• Descriptor: de novo designed TIM barrel DeNovoTIM6 (2 entities in total)
• Functional Keywords: de novo protein design, epistasis, stability landscape, tim barrel, (beta/alfa)8 barrel, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 22553.51

Authors

Romero-Romero, S.,Kordes, S.,Shanmugaratnam, S.,Rodriguez-Romero, A.,Fernandez-Velasco, D.A.,Hocker, B. (deposition date: 2020-05-15, release date: 2021-07-21, Last modification date: 2021-08-04)

• Primary citation: Romero-Romero, S.,Costas, M.,Silva Manzano, D.A.,Kordes, S.,Rojas-Ortega, E.,Tapia, C.,Guerra, Y.,Shanmugaratnam, S.,Rodriguez-Romero, A.,Baker, D.,Hocker, B.,Fernandez-Velasco, D.A.; The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.; J.Mol.Biol., 433:167153-167153, 2021; PubMed: 34271011; DOI: 10.1016/j.jmb.2021.167153

Experimental method

X-RAY DIFFRACTION (2.901 Å)