4FEX
| Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor tyrphostin AG1478 | Descriptor: | ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, KANAMYCIN A, ... | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-05-30 | Release date: | 2012-06-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem.J., 454, 2013
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4FEW
| Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP2 | Descriptor: | 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, ... | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-05-30 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem.J., 454, 2013
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3R0P
| Crystal structure of L-PSP putative endoribonuclease from uncultured organism | Descriptor: | L-PSP putative endoribonuclease | Authors: | Cuff, M.E, Petit, P, Xu, X, Cui, H, Savchenko, A, Yakunin, A.F. | Deposit date: | 2011-03-08 | Release date: | 2011-03-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of L-PSP putative endoribonuclease from uncultured organism To be Published
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2NP3
| Crystal structure of TetR-family regulator (SCO0857) from Streptomyces coelicolor A3. | Descriptor: | Putative TetR-family regulator | Authors: | Koclega, K.D, Xu, X, Chruszcz, M, Gu, J, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-10-26 | Release date: | 2006-11-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of TetR-family regulator (SCO0857) from Streptomyces coelicolor A3. To be Published
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2NP5
| Crystal structure of a transcriptional regulator (RHA1_ro04179) from Rhodococcus sp. Rha1. | Descriptor: | DODECYL-BETA-D-MALTOSIDE, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, Transcriptional regulator | Authors: | Chruszcz, M, Evdokimova, E, Kagan, O, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-10-26 | Release date: | 2006-11-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a transcriptional regulator (RHA1_ro04179) from Rhodococcus sp. Rha1. TO BE PUBLISHED
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3R3S
| Structure of the YghA Oxidoreductase from Salmonella enterica | Descriptor: | FORMIC ACID, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-03-16 | Release date: | 2011-03-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structure of the YghA Oxidoreductase from Salmonella enterica TO BE PUBLISHED
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4PVI
| Crystal structure of GH62 hydrolase in complex with xylotriose | Descriptor: | GH62 hydrolase, PHOSPHATE ION, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | Authors: | Nocek, B, Kaur, A.P, Xu, X, Cui, H, Savchenko, A. | Deposit date: | 2014-03-17 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Crystal structure of GH62 hydrolase in complex with xylotriose TO BE PUBLISHED
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3DCL
| Crystal structure of TM1086 | Descriptor: | CHLORIDE ION, POTASSIUM ION, SULFATE ION, ... | Authors: | Chruszcz, M, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-06-03 | Release date: | 2008-08-05 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of TM1086 To be Published
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3R8Y
| Structure of the Bacillus anthracis tetrahydropicolinate succinyltransferase | Descriptor: | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, CALCIUM ION | Authors: | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-03-24 | Release date: | 2011-04-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the Bacillus anthracis tetrahydropicolinate succinyltransferase TO BE PUBLISHED
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3OYT
| 1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92 | Descriptor: | 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase I, DI(HYDROXYETHYL)ETHER, ... | Authors: | Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Peterson, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-09-23 | Release date: | 2011-01-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | 1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92 To be Published
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3P7M
| Structure of putative lactate dehydrogenase from Francisella tularensis subsp. tularensis SCHU S4 | Descriptor: | Malate dehydrogenase, PHOSPHATE ION | Authors: | Osinski, T, Cymborowski, M, Zimmerman, M.D, Gordon, E, Grimshaw, S, Skarina, T, Chruszcz, M, Savchenko, A, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-10-12 | Release date: | 2010-10-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of putative lactate dehydrogenase from Francisella tularensis subsp. tularensis SCHU S4 To be Published
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3RUY
| Crystal Structure of the Ornithine-oxo acid transaminase RocD from Bacillus anthracis | Descriptor: | Ornithine aminotransferase | Authors: | Anderson, S.M, Wawrzak, Z, Brunzelle, J.S, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-05-05 | Release date: | 2011-05-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal Structure of the Ornithine-oxo acid transaminase RocD from Bacillus anthracis To be Published
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2O0Y
| Crystal structure of putative transcriptional regulator RHA1_ro06953 (IclR-family) from Rhodococcus sp. | Descriptor: | Transcriptional regulator | Authors: | Chruszcz, M, Wang, S, Skarina, T, Onopriyenko, O, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-11-28 | Release date: | 2006-12-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Putative Transcriptional Regul 2 Rha1_Ro06953(Iclr-Family) from Rhodococcus Sp. To be Published
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4E8O
| Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-Ih from Acinetobacter baumannii | Descriptor: | Aac(6')-Ih protein, CHLORIDE ION | Authors: | Stogios, P.J, Minasov, G, Dong, A, Evdokimova, E, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-03-20 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.138 Å) | Cite: | Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes. ACS Infect Dis., 3, 2017
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2P35
| Crystal structure of trans-aconitate methyltransferase from Agrobacterium tumefaciens | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, Trans-aconitate 2-methyltransferase | Authors: | Chang, C, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-03-08 | Release date: | 2007-04-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of trans-aconitate methyltransferase from Agrobacterium tumefaciens To be Published
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2OV9
| Crystal structure of protein RHA08564, thioesterase superfamily protein | Descriptor: | Hypothetical protein, SULFATE ION | Authors: | Chang, C, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-02-13 | Release date: | 2007-03-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of protein RHA08564, thioesterase superfamily protein To be Published
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2LOJ
| Solution NMR structure of TSTM1273 from Salmonella typhimurium LT2, NESG target STT322, CSGID target IDP01027 and OCSP target TSTM1273 | Descriptor: | Putative cytoplasmic protein | Authors: | Wu, B, Yee, A, Houliston, S, Garcia, M, Savchenko, A, Arrowsmith, C.H, Anderson, W.F, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP), Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-01-24 | Release date: | 2012-03-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of TSTM1273 from Salmonella typhimurium LT2, NESG target STT322, CSGID target IDP01027 and OCSP target TSTM1273 To be Published
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4F0Y
| Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-IG from Acinetobacter haemolyticus, apo | Descriptor: | Aminoglycoside N(6')-acetyltransferase type 1, CHLORIDE ION, GLYCEROL, ... | Authors: | Stogios, P.J, Evdokimova, E, Dong, A, Minasov, G, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-05-05 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes. ACS Infect Dis., 3, 2017
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4FCG
| Structure of the leucine-rich repeat domain of the type III effector XCV3220 (XopL) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | Authors: | Singer, A.U, Xu, X, Cui, H, Zimmerman, M.D, Minor, W, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-24 | Release date: | 2012-06-13 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the leucine-rich repeat domain of the type III effector XCV3220 (XopL) To be Published
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2QKO
| Crystal structure of transcriptional regulator RHA06399 from Rhodococcus sp. RHA1 | Descriptor: | Possible transcriptional regulator, TetR family protein | Authors: | Chang, C, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-07-11 | Release date: | 2007-07-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of tetR family protein. To be Published
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2M46
| Solution NMR structure of SACOL0876 from Staphylococcus aureus COL, NESG target ZR353 and CSGID target IDP00841 | Descriptor: | Arsenate reductase, putative | Authors: | Wu, B, Yee, A, Houliston, S, Garcia, M, Savchenko, A, Arrowsmith, C.H, Anderson, W.F, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP), Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-01-29 | Release date: | 2013-02-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of SACOL0876 from Staphylococcus aureus COL, NESG target ZR353 and CSGID target IDP00841 To be Published
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2RFQ
| Crystal structure of 3-HSA hydroxylase from Rhodococcus sp. RHA1 | Descriptor: | 3-HSA hydroxylase, oxygenase, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE | Authors: | Chang, C, Skarina, T, Kagan, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-10-01 | Release date: | 2007-10-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of 3-HSA hydroxylase, oxygenase from Rhodococcus sp. RHA1. To be Published
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3CNI
| Crystal structure of a domain of a putative ABC type-2 transporter from Thermotoga maritima MSB8 | Descriptor: | CALCIUM ION, Putative ABC type-2 transporter | Authors: | Filippova, E.V, Shumilin, I, Tkaczuk, K.L, Cymborowski, M, Chruszcz, M, Xu, X, Que, Q, Savchenko, A, Edwards, A.M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-03-25 | Release date: | 2008-04-08 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural characterization of the putative ABC-type 2 transporter from Thermotoga maritima MSB8. J.Struct.Funct.Genom., 15, 2014
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2PQQ
| Structural Genomics, the crystal structure of the N-terminal domain of a transcriptional regulator from Streptomyces coelicolor A3(2) | Descriptor: | FORMIC ACID, Putative transcriptional regulator | Authors: | Tan, K, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-05-02 | Release date: | 2007-06-05 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of the N-terminal domain of a transcriptional regulator from Streptomyces coelicolor A3(2) To be Published
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2PFS
| Crystal structure of universal stress protein from Nitrosomonas europaea | Descriptor: | CHLORIDE ION, Universal stress protein | Authors: | Chruszcz, M, Evdokimova, E, Cymborowski, M, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-04-05 | Release date: | 2007-05-08 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and functional insight into the universal stress protein family. Evol Appl, 6, 2013
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