8J6M
| SIDT1 protein | Descriptor: | CHOLESTEROL, Green fluorescent protein,SID1 transmembrane family member 1, OLEIC ACID, ... | Authors: | Zhang, J.T, Jiang, D.H. | Deposit date: | 2023-04-26 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structural insights into double-stranded RNA recognition and transport by SID-1. Nat.Struct.Mol.Biol., 2024
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5DIJ
| The crystal structure of CT | Descriptor: | CHLORIDE ION, GLYCEROL, TqaA | Authors: | Zhang, J.R, Tang, Y, Zhou, J.H. | Deposit date: | 2015-09-01 | Release date: | 2016-09-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of nonribosomal peptide macrocyclization in fungi Nat.Chem.Biol., 12, 2016
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5EJD
| The crystal structure of holo T3CT | Descriptor: | 4'-PHOSPHOPANTETHEINE, GLYCEROL, TqaA | Authors: | Zhang, J.R, Tang, Y, Zhou, J.H. | Deposit date: | 2015-11-01 | Release date: | 2016-10-19 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural basis of nonribosomal peptide macrocyclization in fungi Nat.Chem.Biol., 12, 2016
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5EGF
| The crystal structure of SeMet-CT | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, TqaA | Authors: | Zhang, J.R, Tang, Y, Zhou, J.H. | Deposit date: | 2015-10-27 | Release date: | 2016-10-19 | Last modified: | 2020-02-19 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural basis of nonribosomal peptide macrocyclization in fungi Nat.Chem.Biol., 12, 2016
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4RYY
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4RYZ
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7AMT
| Structure of LuxR with DNA (activation) | Descriptor: | DNA (5'-D(P*AP*TP*AP*AP*TP*GP*AP*CP*AP*TP*TP*AP*CP*TP*GP*TP*AP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*TP*AP*CP*AP*GP*TP*AP*AP*TP*GP*TP*CP*AP*TP*TP*AP*T)-3'), HTH-type transcriptional regulator LuxR | Authors: | Liu, B, Reverter, D. | Deposit date: | 2020-10-09 | Release date: | 2021-03-31 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression. Nucleic Acids Res., 49, 2021
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7AMN
| Structure of LuxR with DNA (repression) | Descriptor: | DNA (5'-D(P*TP*AP*TP*TP*GP*AP*TP*AP*AP*AP*AP*TP*TP*AP*TP*CP*AP*AP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*TP*GP*AP*TP*AP*AP*TP*TP*TP*TP*AP*TP*CP*AP*AP*TP*A)-3'), HTH-type transcriptional regulator LuxR | Authors: | Liu, B, Reverter, D. | Deposit date: | 2020-10-09 | Release date: | 2021-03-31 | Last modified: | 2021-04-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Binding site profiles and N-terminal minor groove interactions of the master quorum-sensing regulator LuxR enable flexible control of gene activation and repression. Nucleic Acids Res., 49, 2021
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8FYF
| Human TMEM175-LAMP1 transmembrane domain only complex | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1 | Authors: | Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X. | Deposit date: | 2023-01-26 | Release date: | 2023-06-28 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. Mol.Cell, 83, 2023
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8FY5
| Human TMEM175-LAMP1 full-length complex | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1 | Authors: | Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X. | Deposit date: | 2023-01-25 | Release date: | 2023-06-28 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. Mol.Cell, 83, 2023
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8EJM
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7KGZ
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7KGY
| Beta-glucuronidase from Faecalibacterium prausnitzii bound to the inhibitor UNC10201652-glucuronide | Descriptor: | 8-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5-(morpholin-4-yl)-1,2,3,4-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3 -c]isoquinoline, Beta-glucuronidase, GLYCEROL | Authors: | Simpson, J.B, Redinbo, M.R. | Deposit date: | 2020-10-19 | Release date: | 2021-11-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract. Nat Commun, 13, 2022
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6RX8
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6LMR
| Solution structure of cold shock domain and ssDNA complex | Descriptor: | DNA (5'-D(P*AP*AP*CP*AP*CP*CP*T)-3'), Y-box-binding protein 1 | Authors: | Fan, J, Yang, D. | Deposit date: | 2019-12-26 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation. Nucleic Acids Res., 48, 2020
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6RXA
| EDDS lyase variant D290M/Y320M with bound formate | Descriptor: | Argininosuccinate lyase, FORMIC ACID, GLYCEROL, ... | Authors: | Grandi, E, Poelarends, G.J, Thunnissen, A.M.W.H. | Deposit date: | 2019-06-07 | Release date: | 2019-10-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners. Angew.Chem.Int.Ed.Engl., 59, 2020
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8GXM
| HUMAN SUGP1 433-586 | Descriptor: | SURP and G-patch domain-containing protein 1 | Authors: | Xu, K, Tong, L. | Deposit date: | 2022-09-20 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer. Proc.Natl.Acad.Sci.USA, 119, 2022
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8GXL
| HUMAN SUGP1 433-577 | Descriptor: | SURP and G-patch domain-containing protein 1 | Authors: | Xu, K, Tong, L. | Deposit date: | 2022-09-20 | Release date: | 2022-12-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer. Proc.Natl.Acad.Sci.USA, 119, 2022
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3DJ3
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3DIW
| c-terminal beta-catenin bound TIP-1 structure | Descriptor: | Tax1-binding protein 3, decameric peptide form Catenin beta-1 | Authors: | Shen, Y. | Deposit date: | 2008-06-21 | Release date: | 2008-10-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1 J.Mol.Biol., 384, 2008
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3DJ1
| crystal structure of TIP-1 wild type | Descriptor: | SULFATE ION, Tax1-binding protein 3 | Authors: | Shen, Y. | Deposit date: | 2008-06-21 | Release date: | 2008-10-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1 J.Mol.Biol., 384, 2008
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3K5V
| Structure of Abl kinase in complex with imatinib and GNF-2 | Descriptor: | 3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, ... | Authors: | Cowan-Jacob, S.W, Fendrich, G, Rummel, G, Strauss, A. | Deposit date: | 2009-10-08 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors. Nature, 463, 2010
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6O3S
| NMR solution structure of Luffin P1 | Descriptor: | Ribosome-inactivating protein luffin P1 | Authors: | Rosengren, K.J, Payne, C. | Deposit date: | 2019-02-27 | Release date: | 2019-04-24 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | An Ancient Peptide Family Buried within Vicilin Precursors. Acs Chem.Biol., 14, 2019
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6O3Q
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4NSO
| Crystal structure of the effector-immunity protein complex | Descriptor: | Effector protein, Immunity protein | Authors: | Dong, C. | Deposit date: | 2013-11-28 | Release date: | 2014-04-16 | Last modified: | 2014-06-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for recognition of the type VI spike protein VgrG3 by a cognate immunity protein. Febs Lett., 588, 2014
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