4RYY

Crystal structure of RPE65 in complex with R-emixustat and palmitate

Summary for 4RYY

Related3FSN 4RSC 4RYX 4RYZ
DescriptorRetinoid isomerohydrolase, FE (II) ION, PALMITIC ACID, ... (5 entities in total)
Functional Keywords7-bladed beta propeller, monotopic membrane protein, non-heme iron enzyme, retinoid isomerase, isomerase
Biological sourceBos taurus (bovine,cow,domestic cattle,domestic cow)
Cellular locationCytoplasm Q28175
Total number of polymer chains2
Total molecular weight123021.37
Authors
Kiser, P.D.,Palczewski, K. (deposition date: 2014-12-17, release date: 2015-05-27)
Primary citation
Zhang, J.,Kiser, P.D.,Badiee, M.,Palczewska, G.,Golczak, M.,Tochtrop, G.P.,Palczewski, K.
The Janus face of primary amine compounds in visual cycle modulation
To be Published,
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.216200.9%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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