Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5KE7
DownloadVisualize
BU of 5ke7 by Molmil
mouse Klf4 ZnF1-3 and TpG/MpA sequence DNA complex structure
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*AP*CP*CP*TP*C)-3'), ...
Authors:Hashimoto, H, Cheng, X.
Deposit date:2016-06-09
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5K5I
DownloadVisualize
BU of 5k5i by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P65
Descriptor: DNA (5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*GP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*G)-3'), SULFATE ION, ...
Authors:Hashimoto, H, Cheng, X.
Deposit date:2016-05-23
Release date:2017-05-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5KL7
DownloadVisualize
BU of 5kl7 by Molmil
Wilms Tumor Protein (WT1) ZnF2-4Q369R in complex with carboxylated DNA
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ...
Authors:Hashimoto, H, Cheng, X.
Deposit date:2016-06-23
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.579 Å)
Cite:Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016
2QRV
DownloadVisualize
BU of 2qrv by Molmil
Structure of Dnmt3a-Dnmt3L C-terminal domain complex
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Jia, D, Cheng, X.
Deposit date:2007-07-29
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.
Nature, 449, 2007
2ORE
DownloadVisualize
BU of 2ore by Molmil
Binary Structure of Escherichia coli DNA Adenine Methyltransferase and S-adenosylhomocysteine
Descriptor: DNA adenine methylase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION
Authors:Horton, J.R, Cheng, X.
Deposit date:2007-02-02
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Two Alternative Conformations of S-Adenosyl-L-homocysteine Bound to Escherichia coli DNA Adenine Methyltransferase and the Implication of Conformational Changes in Regulating the Catalytic Cycle.
J.Biol.Chem., 282, 2007
2PUY
DownloadVisualize
BU of 2puy by Molmil
Crystal Structure of the BHC80 PHD finger
Descriptor: Histone H3, PHD finger protein 21A, ZINC ION
Authors:Horton, J.R, Cheng, X, Collins, R.E.
Deposit date:2007-05-09
Release date:2007-08-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.
Nature, 448, 2007
3SVM
DownloadVisualize
BU of 3svm by Molmil
Human MPP8 - human DNMT3AK47me2 peptide
Descriptor: DNA (cytosine-5)-methyltransferase 3A, M-phase phosphoprotein 8
Authors:Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
Deposit date:2011-07-12
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
3SWC
DownloadVisualize
BU of 3swc by Molmil
GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me2 peptide
Descriptor: DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
Deposit date:2011-07-13
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
6UKG
DownloadVisualize
BU of 6ukg by Molmil
HhaI endonuclease in Complex With DNA in space group P21 (pH 4.2)
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*AP*GP*CP*GP*CP*AP*AP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*GP*A)-3'), ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2019-10-04
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6UKF
DownloadVisualize
BU of 6ukf by Molmil
HhaI endonuclease in Complex with DNA at 1 Angstrom Resolution
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2019-10-04
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
3SW9
DownloadVisualize
BU of 3sw9 by Molmil
GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me0 peptide
Descriptor: DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, SINEFUNGIN, ...
Authors:Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
Deposit date:2011-07-13
Release date:2011-12-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
6UKI
DownloadVisualize
BU of 6uki by Molmil
HhaI endonuclease in Complex with DNA in space group P212121 (pH 6.0)
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*GP*A)-3'), ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2019-10-04
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6OX1
DownloadVisualize
BU of 6ox1 by Molmil
SETD3 in Complex with an Actin Peptide with Target Histidine Partially Methylated
Descriptor: 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6V62
DownloadVisualize
BU of 6v62 by Molmil
SETD3 double mutant (N255F/W273A) in Complex with an Actin Peptide with His73 Replaced with Lysine
Descriptor: 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ...
Authors:Dai, S, Horton, J.R, Cheng, X.
Deposit date:2019-12-04
Release date:2020-01-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
6OX4
DownloadVisualize
BU of 6ox4 by Molmil
A SETD3 Mutant (N255A) in Complex with an Actin Peptide
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6OX0
DownloadVisualize
BU of 6ox0 by Molmil
SETD3 in Complex with an Actin Peptide with Sinefungin Replacing SAH as Cofactor
Descriptor: 1,2-ETHANEDIOL, Actin Peptide, Histone-lysine N-methyltransferase setd3, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.755 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6OX3
DownloadVisualize
BU of 6ox3 by Molmil
SETD3 in Complex with an Actin Peptide with His73 Replaced with Lysine
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.785 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6OX5
DownloadVisualize
BU of 6ox5 by Molmil
A SETD3 Mutant (N255A) in Complex with an Actin Peptide with His73 Replaced with Lysine
Descriptor: 1,2-ETHANEDIOL, Actin Peptide, Actin-histidine N-methyltransferase, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6UKH
DownloadVisualize
BU of 6ukh by Molmil
HhaI endonuclease in Complex with DNA in space group P41212 (pH 6.0)
Descriptor: CALCIUM ION, DNA (5'-D(*CP*CP*AP*AP*GP*CP*GP*CP*AP*AP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*G)-3'), ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2019-10-04
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
4PAR
DownloadVisualize
BU of 4par by Molmil
The 5-Hydroxymethylcytosine-Specific Restriction Enzyme AbaSI in a Complex with Product-like DNA
Descriptor: 1,2-ETHANEDIOL, DNA 14-MER, DNA 18-MER, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-04-09
Release date:2014-06-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA.
Nucleic Acids Res., 42, 2014
6UKE
DownloadVisualize
BU of 6uke by Molmil
HhaI endonuclease in Complex with Iodine-Labelled DNA
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2019-10-04
Release date:2019-12-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
6OX2
DownloadVisualize
BU of 6ox2 by Molmil
SETD3in Complex with an Actin Peptide with the Target Histidine Fully Methylated
Descriptor: 1,2-ETHANEDIOL, Actin Peptide, GLYCEROL, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.089 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6V63
DownloadVisualize
BU of 6v63 by Molmil
SETD3 WT in Complex with an Actin Peptide with His73 Replaced with Glutamine
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Actin, ...
Authors:Dai, S, Horton, J.R, Cheng, X.
Deposit date:2019-12-04
Release date:2020-01-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
1FJX
DownloadVisualize
BU of 1fjx by Molmil
STRUCTURE OF TERNARY COMPLEX OF HHAI METHYLTRANSFERASE MUTANT (T250G) IN COMPLEX WITH DNA AND ADOHCY
Descriptor: DNA (5'-D(*TP*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), HHAI DNA METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Vilkaitis, G, Dong, A, Weinhold, E, Cheng, X, Klimasauskas, S.
Deposit date:2000-08-08
Release date:2000-12-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Functional roles of the conserved threonine 250 in the target recognition domain of HhaI DNA methyltransferase.
J.Biol.Chem., 275, 2000
7RFK
DownloadVisualize
BU of 7rfk by Molmil
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Inhibitor Sinefungin
Descriptor: 1,2-ETHANEDIOL, DNA Strand 1, DNA Strand 2, ...
Authors:Horton, J.R, Cheng, X, Zhou, J.
Deposit date:2021-07-14
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Repurposing epigenetic inhibitors to target the Clostridioides difficile- specific DNA adenine methyltransferase and sporulation regulator CamA.
Epigenetics, 17, 2022

221716

数据于2024-06-26公开中

PDB statisticsPDBj update infoContact PDBjnumon