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3M45
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BU of 3m45 by Molmil
Crystal structure of Ig1 domain of mouse SynCAM 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 2
Authors:Yue, L, Modis, Y.
Deposit date:2010-03-10
Release date:2010-09-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion.
J.Biol.Chem., 285, 2010
5VSL
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BU of 5vsl by Molmil
Crystal structure of viperin with bound [4Fe-4S] cluster and S-adenosylhomocysteine (SAH)
Descriptor: IRON/SULFUR CLUSTER, Radical S-adenosyl methionine domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E.
Deposit date:2017-05-11
Release date:2017-06-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.972 Å)
Cite:Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VSM
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BU of 5vsm by Molmil
Crystal structure of viperin with bound [4Fe-4S] cluster, 5'-deoxyadenosine, and L-methionine
Descriptor: 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ...
Authors:Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E.
Deposit date:2017-05-11
Release date:2017-06-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
9F3P
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BU of 9f3p by Molmil
Cryo-EM structure of the A946T MDA5-dsRNA filament
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), RNA (5'-R(P*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*GP*AP*C)-3'), ...
Authors:Singh, R, Herrero del Valle, A, Modis, Y.
Deposit date:2024-04-25
Release date:2025-02-26
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
9F2W
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BU of 9f2w by Molmil
Cryo-EM structure of the I923V MDA5-dsRNA filament in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
Authors:Singh, R, Herrero del Valle, A, Modis, Y.
Deposit date:2024-04-24
Release date:2025-02-26
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (4.21 Å)
Cite:Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
9F2L
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BU of 9f2l by Molmil
Cryo-EM structure of the I923V MDA5-dsRNA filament with ADP-AlF4 bound and 73-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ...
Authors:Singh, R, Herrero del Valle, A, Modis, Y.
Deposit date:2024-04-23
Release date:2025-02-26
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
9F20
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BU of 9f20 by Molmil
Cryo-EM structure of the I923V MDA5-dsRNA filament with ADP-AlF4 bound and 88-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), ...
Authors:Singh, R, Herrero del Valle, A, Modis, Y.
Deposit date:2024-04-20
Release date:2025-02-26
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
9F1U
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BU of 9f1u by Molmil
Cryo-EM structure of the I923V MDA5-dsRNA filament with ADP-AlF4 bound and 81-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
Authors:Singh, R, Herrero del Valle, A, Modis, Y.
Deposit date:2024-04-20
Release date:2025-02-26
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
9F0J
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BU of 9f0j by Molmil
Cryo-EM structure of the I923V MDA5-dsRNA filament without nucleotide
Descriptor: Interferon-induced helicase C domain-containing protein 1, RNA (5'-CGUCAUGCGCAUGGA-3'), RNA (5'-UCCAUGCGCAUGACG-3'), ...
Authors:Singh, R, Herrero del Valle, A, Modis, Y.
Deposit date:2024-04-16
Release date:2025-02-26
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Molecular basis of autoimmune disease protection by MDA5 variants.
Cell Rep, 44, 2025
3NEC
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BU of 3nec by Molmil
Crystal Structure of Toxoplasma gondii Profilin
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Inflammatory profilin, SULFATE ION
Authors:Kucera, K, Modis, Y.
Deposit date:2010-06-08
Release date:2010-09-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11.
J.Mol.Biol., 403, 2010
8P0E
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BU of 8p0e by Molmil
Rubella virus p150 macro domain in complex with ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural polyprotein p200
Authors:Stoll, G.A, Modis, Y.
Deposit date:2023-05-10
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Crystal structure and biochemical activity of the macrodomain from rubella virus p150.
J.Virol., 98, 2024
8P0C
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BU of 8p0c by Molmil
Rubella virus p150 macro domain (apo)
Descriptor: Non-structural polyprotein p200
Authors:Stoll, G.A, Modis, Y.
Deposit date:2023-05-10
Release date:2024-01-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure and biochemical activity of the macrodomain from rubella virus p150.
J.Virol., 98, 2024
8QFB
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BU of 8qfb by Molmil
Crystal structure of human MPP8 C-terminal region (residues 565-860)
Descriptor: M-phase phosphoprotein 8
Authors:Prigozhin, D.M, Modis, Y.
Deposit date:2023-09-04
Release date:2024-09-11
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structure and Methyl-lysine Binding Selectivity of the HUSH Complex Subunit MPP8.
J.Mol.Biol., 437, 2024
6T1B
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BU of 6t1b by Molmil
Crystal structure of YlmD from Geobacillus stearothermophilus in complex with inosine
Descriptor: INOSINE, YlmD, ZINC ION
Authors:Reikine, S, Modis, Y.
Deposit date:2019-10-03
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle.
Cell, 180, 2020
6T0Y
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BU of 6t0y by Molmil
Crystal structure of YlmD from Geobacillus stearothermophilus
Descriptor: Polyphenol oxidase, ZINC ION
Authors:Reikine, S, Modis, Y.
Deposit date:2019-10-03
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle.
Cell, 180, 2020
7NIQ
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BU of 7niq by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(Major class)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-13
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
7NIC
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BU of 7nic by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(minor class)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-11
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
7NGA
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BU of 7nga by Molmil
CryoEM structure of the MDA5-dsRNA filament in complex with ADP with 88-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*G)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-02-08
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
1RH5
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BU of 1rh5 by Molmil
The structure of a protein conducting channel
Descriptor: Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta
Authors:van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A.
Deposit date:2003-11-13
Release date:2004-01-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:X-ray structure of a protein-conducting channel
Nature, 427, 2004
7BKQ
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BU of 7bkq by Molmil
CryoEM structure of MDA5-dsRNA filament in complex with ADP with 92-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Isoform 2 of Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-01-17
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
7BKP
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BU of 7bkp by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ...
Authors:Singh, R, Herrero del Valle, A, Yu, Q, Modis, Y.
Deposit date:2021-01-16
Release date:2021-11-17
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
1RHZ
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BU of 1rhz by Molmil
The structure of a protein conducting channel
Descriptor: Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta
Authors:van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A.
Deposit date:2003-11-15
Release date:2004-01-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of a protein-conducting channel.
Nature, 427, 2004
4JNT
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BU of 4jnt by Molmil
Crystal structure of the ectodomain of Bovine viral diarrhea virus 1 E2 envelope protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2
Authors:Li, Y, Wang, J, Modis, Y.
Deposit date:2013-03-15
Release date:2013-04-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (4.09 Å)
Cite:Crystal structure of glycoprotein E2 from bovine viral diarrhea virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HJ1
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BU of 4hj1 by Molmil
Crystal structure of glycoprotein C from Rift Valley Fever Virus (glycosylated)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN, ...
Authors:Dessau, M, Modis, Y.
Deposit date:2012-10-12
Release date:2013-01-16
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of glycoprotein C from Rift Valley fever virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HJC
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BU of 4hjc by Molmil
Crystal structure of glycoprotein C from Rift Valley Fever Virus (non-glycosylated)
Descriptor: ENVELOPE GLYCOPROTEIN
Authors:Dessau, M, Modis, Y.
Deposit date:2012-10-12
Release date:2013-01-16
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (4.15 Å)
Cite:Crystal structure of glycoprotein C from Rift Valley fever virus.
Proc.Natl.Acad.Sci.USA, 110, 2013

238582

数据于2025-07-09公开中

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