1WOH
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![BU of 1woh by Molmil](/molmil-images/mine/1woh) | Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily | Descriptor: | agmatinase | Authors: | Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W. | Deposit date: | 2004-08-18 | Release date: | 2004-09-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily J.Biol.Chem., 279, 2004
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1WOI
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![BU of 1woi by Molmil](/molmil-images/mine/1woi) | Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily | Descriptor: | MANGANESE (II) ION, agmatinase | Authors: | Ahn, H.J, Kim, K.H, Lee, J, Ha, J.-Y, Lee, H.H, Kim, D, Yoon, H.-J, Kwon, A.-R, Suh, S.W. | Deposit date: | 2004-08-18 | Release date: | 2004-09-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily J.Biol.Chem., 279, 2004
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5WY8
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![BU of 5wy8 by Molmil](/molmil-images/mine/5wy8) | Crystal structure of PTP delta Ig1-Ig3 in complex with IL1RAPL1 Ig1-Ig3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, ... | Authors: | Kim, H.M, Won, S.Y, Kim, D. | Deposit date: | 2017-01-11 | Release date: | 2017-11-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | LAR-RPTP Clustering Is Modulated by Competitive Binding between Synaptic Adhesion Partners and Heparan Sulfate Front Mol Neurosci, 10, 2017
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5GUY
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![BU of 5guy by Molmil](/molmil-images/mine/5guy) | Structural and functional study of chuY from E. coli CFT073 strain | Descriptor: | Uncharacterized protein chuY | Authors: | Kim, H, Choi, J, HA, S.C, Chaurasia, A.K, Kim, D, Kim, K.K. | Deposit date: | 2016-08-31 | Release date: | 2017-03-08 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Structural and functional study of ChuY from Escherichia coli strain CFT073 Biochem. Biophys. Res. Commun., 482, 2017
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5J6X
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![BU of 5j6x by Molmil](/molmil-images/mine/5j6x) | |
4RCA
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![BU of 4rca by Molmil](/molmil-images/mine/4rca) | Crystal structure of human PTPdelta and human Slitrk1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta, SLIT and NTRK-like protein 1, ... | Authors: | Kim, H.M, Park, B.S, Kim, D, Lee, S.G. | Deposit date: | 2014-09-15 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9908 Å) | Cite: | Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion. Nat Commun, 5, 2014
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2Q9T
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![BU of 2q9t by Molmil](/molmil-images/mine/2q9t) | High-resolution structure of the DING protein from Pseudomonas fluorescens | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DING, ... | Authors: | Moniot, S, Ahn, S, Elias, M, Kim, D, Scott, K, Chabriere, E. | Deposit date: | 2007-06-14 | Release date: | 2008-06-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structure-function relationships in a bacterial DING protein. Febs Lett., 581, 2007
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7YQ8
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![BU of 7yq8 by Molmil](/molmil-images/mine/7yq8) | Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, 50-mer DNA, DNA topoisomerase 2-beta, ... | Authors: | Naganuma, M, Ehara, H, Kim, D, Nakagawa, R, Cong, A, Bu, H, Jeong, J, Jang, J, Schellenberg, M.J, Bunch, H, Sekine, S. | Deposit date: | 2022-08-05 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes. Nat Commun, 14, 2023
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4QR0
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![BU of 4qr0 by Molmil](/molmil-images/mine/4qr0) | Crystal structure of Streptococcus pyogenes Cas2 at pH 5.6 | Descriptor: | CRISPR-associated endoribonuclease Cas2 | Authors: | Bae, E, Ka, D, Kim, D. | Deposit date: | 2014-06-30 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions Biochem.Biophys.Res.Commun., 451, 2014
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4QR1
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![BU of 4qr1 by Molmil](/molmil-images/mine/4qr1) | Crystal structure of Streptococcus pyogenes Cas2 at pH 6.5 | Descriptor: | CRISPR-associated endoribonuclease Cas2 | Authors: | Bae, E, Ka, D, Kim, D. | Deposit date: | 2014-06-30 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.193 Å) | Cite: | Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions Biochem.Biophys.Res.Commun., 451, 2014
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4QR2
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![BU of 4qr2 by Molmil](/molmil-images/mine/4qr2) | Crystal structure of Streptococcus pyogenes Cas2 at pH 7.5 | Descriptor: | CRISPR-associated endoribonuclease Cas2 | Authors: | Bae, E, Ka, D, Kim, D. | Deposit date: | 2014-06-30 | Release date: | 2014-11-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions Biochem.Biophys.Res.Commun., 451, 2014
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8W35
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![BU of 8w35 by Molmil](/molmil-images/mine/8w35) | Aca2 from Pectobacterium phage ZF40 bound to RNA | Descriptor: | Anti-CRISPR associated (Aca) protein, Aca2, IR2 and IR-RBS RNA | Authors: | Wilkinson, M.E, Birkholz, N, Kimanius, D, Fineran, P.C. | Deposit date: | 2024-02-21 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein. Nature, 631, 2024
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1TH1
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![BU of 1th1 by Molmil](/molmil-images/mine/1th1) | Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment | Descriptor: | Adenomatous polyposis coli protein, Beta-catenin | Authors: | Xing, Y, Clements, W.K, Le Trong, I, Hinds, T.R, Stenkamp, R, Kimelman, D, Xu, W. | Deposit date: | 2004-05-31 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of a beta-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function. Mol.Cell, 15, 2004
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7AAP
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![BU of 7aap by Molmil](/molmil-images/mine/7aap) | Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP | Descriptor: | MAGNESIUM ION, Non-structural protein 12, Non-structural protein 7, ... | Authors: | Naydenova, K, Muir, K.W, Wu, L.F, Zhang, Z, Coscia, F, Peet, M, Castro-Hartman, P, Qian, P, Sader, K, Dent, K, Kimanius, D, Sutherland, J.D, Lowe, J, Barford, D, Russo, C.J. | Deposit date: | 2020-09-04 | Release date: | 2020-09-23 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP. Proc.Natl.Acad.Sci.USA, 118, 2021
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5OOL
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![BU of 5ool by Molmil](/molmil-images/mine/5ool) | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | Deposit date: | 2017-08-08 | Release date: | 2017-09-13 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structures of the human mitochondrial ribosome in native states of assembly. Nat. Struct. Mol. Biol., 24, 2017
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5OOM
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![BU of 5oom by Molmil](/molmil-images/mine/5oom) | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | Deposit date: | 2017-08-08 | Release date: | 2017-09-13 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structures of the human mitochondrial ribosome in native states of assembly. Nat. Struct. Mol. Biol., 24, 2017
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6ERI
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![BU of 6eri by Molmil](/molmil-images/mine/6eri) | Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10 alpha, ... | Authors: | Perez Borema, A, Aibara, S, Paul, B, Tobiasson, V, Kimanius, D, Forsberg, B.O, Wallden, K, Lindahl, E, Amunts, A. | Deposit date: | 2017-10-18 | Release date: | 2018-04-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor. Nat Plants, 4, 2018
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1LUJ
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![BU of 1luj by Molmil](/molmil-images/mine/1luj) | Crystal Structure of the Beta-catenin/ICAT Complex | Descriptor: | Beta-catenin-interacting protein 1, Catenin beta-1 | Authors: | Graham, T.A, Clements, W.K, Kimelman, D, Xu, W. | Deposit date: | 2002-05-22 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT. Mol.Cell, 10, 2002
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1QZ7
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![BU of 1qz7 by Molmil](/molmil-images/mine/1qz7) | Beta-catenin binding domain of Axin in complex with beta-catenin | Descriptor: | Axin, Beta-catenin | Authors: | Xing, Y, Clements, W.K, Kimelman, D, Xu, W. | Deposit date: | 2003-09-15 | Release date: | 2003-11-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the {beta}-catenin destruction complex GENES DEV., 17, 2003
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1G3J
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![BU of 1g3j by Molmil](/molmil-images/mine/1g3j) | CRYSTAL STRUCTURE OF THE XTCF3-CBD/BETA-CATENIN ARMADILLO REPEAT COMPLEX | Descriptor: | BETA-CATENIN ARMADILLO REPEAT REGION, TCF3-CBD (CATENIN BINDING DOMAIN) | Authors: | Graham, T.A, Weaver, C, Mao, F, Kimelman, D, Xu, W. | Deposit date: | 2000-10-24 | Release date: | 2000-12-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of a beta-catenin/Tcf complex. Cell(Cambridge,Mass.), 103, 2000
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1JDH
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![BU of 1jdh by Molmil](/molmil-images/mine/1jdh) | CRYSTAL STRUCTURE OF BETA-CATENIN AND HTCF-4 | Descriptor: | BETA-CATENIN, hTcf-4 | Authors: | Graham, T.A, Ferkey, D.M, Mao, F, Kimelman, D, Xu, W. | Deposit date: | 2001-06-13 | Release date: | 2001-12-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tcf4 can specifically recognize beta-catenin using alternative conformations. Nat.Struct.Biol., 8, 2001
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3ZHK
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![BU of 3zhk by Molmil](/molmil-images/mine/3zhk) | |
3ZHD
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3ZHL
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8AZR
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![BU of 8azr by Molmil](/molmil-images/mine/8azr) | KRAS in complex with precursor 1 | Descriptor: | (4~{S})-2-azanyl-4-[3-[6-[(2~{S})-2,4-dimethylpiperazin-1-yl]pyridin-2-yl]-1,2,4-oxadiazol-5-yl]-4-methyl-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... | Authors: | Boettcher, J, Herdeis, L. | Deposit date: | 2022-09-06 | Release date: | 2023-06-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Pan-KRAS inhibitor disables oncogenic signalling and tumour growth. Nature, 619, 2023
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