6CFH
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6CB9
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![BU of 6cb9 by Molmil](/molmil-images/mine/6cb9) | Segment AALQSS from the low complexity domain of TDP-43, residues 328-333 | Descriptor: | AALQSS | Authors: | Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-02-02 | Release date: | 2018-04-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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6CEW
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![BU of 6cew by Molmil](/molmil-images/mine/6cew) | Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326 | Descriptor: | AMMAAA | Authors: | Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-02-12 | Release date: | 2018-04-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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6CF4
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![BU of 6cf4 by Molmil](/molmil-images/mine/6cf4) | Segment NFGTFS, with familial mutation A315T and phosphorylated threonine, from the low complexity domain of TDP-43, residues 312-317 | Descriptor: | NFGTFS | Authors: | Guenther, E.L, Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-02-13 | Release date: | 2018-05-23 | Last modified: | 2021-06-30 | Method: | ELECTRON CRYSTALLOGRAPHY (0.75 Å) | Cite: | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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7K3C
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![BU of 7k3c by Molmil](/molmil-images/mine/7k3c) | SGMGGIT segment 58-64 from Keratin-8 | Descriptor: | ETHANOL, SGMGGIT segment 58-64 from the low complexity domain of Keratin-8, TRIETHYLENE GLYCOL | Authors: | Murray, K.A, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2020-09-11 | Release date: | 2021-11-10 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29, 2022
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7K3Y
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![BU of 7k3y by Molmil](/molmil-images/mine/7k3y) | GGYAGAS segment 52-58 from Keratin-8 | Descriptor: | GGYAGAS segment 52-58 from the low complexity domain of Keratin-8 | Authors: | Murray, K.A, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2020-09-14 | Release date: | 2021-11-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29, 2022
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7K3X
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6UFR
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![BU of 6ufr by Molmil](/molmil-images/mine/6ufr) | Structure of recombinantly assembled E46K alpha-synuclein fibrils | Descriptor: | Alpha-synuclein | Authors: | Eisenberg, D.S, Boyer, D.R, Sawaya, M.R, Li, B, Jiang, L. | Deposit date: | 2019-09-24 | Release date: | 2020-02-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | The alpha-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure. Proc.Natl.Acad.Sci.USA, 117, 2020
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