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7TQG
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BU of 7tqg by Molmil
Crystal Structure of IOMA Fab inferred germline
Descriptor: IOMA iGL Fab Heavy Chain, IOMA iGL Fab Light Chain
Authors:Gristick, H.B, Bjorkman, P.J.
Deposit date:2022-01-26
Release date:2023-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.
Sci Immunol, 8, 2023
7U0C
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BU of 7u0c by Molmil
Crystal structure of broadly neutralizing antibody HEPC3.4
Descriptor: HEPC3.4 Fab Heavy Chain, HEPC3.4 Fab Light Chain
Authors:Flyak, A.I, Bjorkman, P.J.
Deposit date:2022-02-17
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
7U0B
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BU of 7u0b by Molmil
Crystal structure of broadly neutralizing antibody HEPC3.1
Descriptor: HEPC3.1 Fab Heavy Chain, HEPC3.1 Fab Light Chain
Authors:Flyak, A.I, Bjorkman, P.J.
Deposit date:2022-02-17
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
6XCM
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BU of 6xcm by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6XCA
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BU of 6xca by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C105
Descriptor: C105 Heavy Chain, C105 Light Chain, SULFATE ION
Authors:Sharaf, N.G, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6XCN
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BU of 6xcn by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
4JDT
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BU of 4jdt by Molmil
Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
Authors:Scharf, L, Diskin, R, Bjorkman, P.J.
Deposit date:2013-02-25
Release date:2013-03-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4NHG
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BU of 4nhg by Molmil
Crystal Structure of 2G12 IgG Dimer
Descriptor: 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein
Authors:Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J.
Deposit date:2013-11-05
Release date:2014-02-26
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (8.001 Å)
Cite:Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5, 2013
4NHH
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BU of 4nhh by Molmil
Structure of 2G12 IgG Dimer
Descriptor: 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein
Authors:Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J.
Deposit date:2013-11-05
Release date:2014-02-26
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5, 2013
3FRU
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BU of 3fru by Molmil
NEONATAL FC RECEPTOR, PH 6.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-2-MICROGLOBULIN, BETA-MERCAPTOETHANOL, ...
Authors:Vaughn, D.E, Burmeister, W.P, Bjorkman, P.J.
Deposit date:1997-12-22
Release date:1998-06-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of pH-dependent antibody binding by the neonatal Fc receptor.
Structure, 6, 1998
7UZD
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BU of 7uzd by Molmil
Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, HSW-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HSW-2 Fab heavy chain, HSW-2 Fab light chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZC
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BU of 7uzc by Molmil
Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, M8a-34
Descriptor: M8a-34 Fab heavy chain, M8a-34 Fab light chain, Spike protein S1, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UCG
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BU of 7ucg by Molmil
Structure of the DU422 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
Descriptor: 10-1074 Fab heavy chain, 10-1074 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2022-03-16
Release date:2022-08-17
Last modified:2022-09-07
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UZ9
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BU of 7uz9 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-34
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-34 Fab heavy chain, M8a-34 Fab light chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ8
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BU of 7uz8 by Molmil
Structure of the SARS-CoV-2 Omicron BA.1 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-31 Fab heavy chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZA
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BU of 7uza by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, HSW-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HSW-1 Fab heavy chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ5
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BU of 7uz5 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-6 Fab heavy chain, M8a-6 Fab light chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ6
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BU of 7uz6 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-28
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-28 Fab heavy chain, M8a-28 Fab light chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ4
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BU of 7uz4 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-3 Fab heavy chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ7
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BU of 7uz7 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-31 Fab heavy chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZB
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BU of 7uzb by Molmil
Structure of the SARS-CoV-2 S S1 doamin in complex with the mouse antibody Fab fragment, HSW-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HSW-2 Fab heavy chain, HSW-2 Fab light chain, ...
Authors:Fan, C, Bjorkman, P.J.
Deposit date:2022-05-08
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UGO
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BU of 7ugo by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGM
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BU of 7ugm by Molmil
Crystal Structure of BG24-iGL CDR3mat Fab
Descriptor: BG24-iGL CDR3mat Fab heavy chain, BG24-iGL CDR3mat Fab light chain
Authors:Dam, K.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGQ
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BU of 7ugq by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline CDRL1 and 10-1074 Fabs in complex with HIV-1 Env 6405-SOSIP.664
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGP
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BU of 7ugp by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022

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数据于2024-08-21公开中

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