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7R8N
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BU of 7r8n by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C051
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C051 Fab Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-06-26
Release date:2021-08-04
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7R8L
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BU of 7r8l by Molmil
Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody C099 and CR3022
Descriptor: C099 Fab Heavy Chain, C099 Fab Light Chain, CR3022 Fab heavy chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-06-26
Release date:2021-08-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7S0D
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BU of 7s0d by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-014
Descriptor: N-612-014 Fab Heavy Chain, N-612-014 Light Chain, Spike glycoprotein
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-08-30
Release date:2021-10-06
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
7S0E
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BU of 7s0e by Molmil
Structure of the SARS-CoV-2 S1 subunit in complex with antibody N-612-004
Descriptor: N-612-004 Fab heavy chain, N-612-004 Light Chain, Spike glycoprotein
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-08-30
Release date:2021-10-06
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
7S0C
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BU of 7s0c by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-017
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-612-017 Fab Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-08-30
Release date:2021-10-06
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
6OI7
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BU of 6oi7 by Molmil
Se-Met structure of apo- Escherichia coli dGTPase
Descriptor: Deoxyguanosinetriphosphate triphosphohydrolase, MANGANESE (II) ION, SULFATE ION
Authors:Calero, G, Barnes, C.O, Wu, Y.
Deposit date:2019-04-08
Release date:2019-05-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
7UAP
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BU of 7uap by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the neutralizing antibody Fab fragment, C1520
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C1520 Fab Heavy Chain, ...
Authors:Barnes, C.O.
Deposit date:2022-03-13
Release date:2022-04-27
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.
Immunity, 55, 2022
7UAR
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BU of 7uar by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the neutralizing antibody Fab fragment, C1717
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C1717 Fab Heavy Chain, ...
Authors:Barnes, C.O.
Deposit date:2022-03-13
Release date:2022-04-27
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.
Immunity, 55, 2022
7UAQ
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BU of 7uaq by Molmil
Structure of the SARS-CoV-2 NTD in complex with C1520, local refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C1520 Fab Heavy Chain, ...
Authors:Barnes, C.O.
Deposit date:2022-03-13
Release date:2022-04-27
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.
Immunity, 55, 2022
6OKQ
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BU of 6okq by Molmil
Crystal structure of the SF12 Fab
Descriptor: SF12 Fab Heavy Chain,SF12 Fab Heavy Chain, SF12 Fab Light Chain,SF12 Fab Light Chain
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2019-04-14
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
6OKP
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BU of 6okp by Molmil
B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074
Descriptor: 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2019-04-14
Release date:2019-06-05
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
7RKV
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BU of 7rkv by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C118 Fab Heavy Chain, C118 Fab Light Chain, ...
Authors:Barnes, C.O, Jette, C.A, Bjorkman, P.J.
Deposit date:2021-07-22
Release date:2021-09-22
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Cell Rep, 36, 2021
7K8N
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BU of 7k8n by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102
Descriptor: C102 Fab Heavy Chain, C102 Fab Light Chain, DI(HYDROXYETHYL)ETHER, ...
Authors:Jette, C.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8X
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BU of 7k8x by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ...
Authors:Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8Q
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BU of 7k8q by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C121
Descriptor: C121 Fab Heavy Chain, C121 Fab Light Chain, GLYCEROL
Authors:Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8Y
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BU of 7k8y by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ...
Authors:Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8P
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BU of 7k8p by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C110
Descriptor: C110 Fab Heavy Chain, C110 Fab Light Chain
Authors:Dam, K.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8M
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BU of 7k8m by Molmil
Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C102
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C102 Fab Heavy Chain, C102 Fab Light Chain, ...
Authors:Jette, C.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8V
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BU of 7k8v by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C110 Fab Heavy Chain, ...
Authors:Dam, K.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8O
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BU of 7k8o by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C002
Descriptor: C002 Fab Heavy Chain, C002 Fab Light Chain, GLYCEROL, ...
Authors:Jette, C.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8W
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BU of 7k8w by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C119 Fab Heavy Chain, ...
Authors:Sharaf, N.G, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7KDE
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BU of 7kde by Molmil
BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-10-08
Release date:2020-10-28
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.
Elife, 9, 2020
7K8T
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BU of 7k8t by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ...
Authors:Malyutin, A.G, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8R
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BU of 7k8r by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C135
Descriptor: C135 Fab Heavy Chain, C135 Fab Light Chain, GLYCEROL
Authors:Jette, C.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7KL9
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BU of 7kl9 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the ACE2 protein decoy, CTC-445.2 (State 4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CTC-445.2 inhibitor, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-10-29
Release date:2020-11-11
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2.
Science, 370, 2020

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数据于2024-11-06公开中

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